New Artificial Neurons Will Help Heart Patients

Neurodegenerative diseases and heart disease have long been a major cause of concern for countless patients and their families across the globe. People who suffer from Alzheimer's and other neurodegenerative disorders, as well as heart failure face insurmountable challenges that can, at times, be impossible to overcome.

However, hope might be on the horizon!

Artificial neurons - a new discovery that might help fight heart ailments 

An international team of scientists,  has invented what is being called tiny "brain chips". These are basically artificial nerve cells – the first of their kind in the world – on silicon chips that will help fight chronic ailments like Alzheimer's, heart failure and other neurodegenerative diseases.

The researchers have explained that these artificial neurons could help replace the neurons that have been lost to degenerative diseases. This is primarily the case in people who use medical implants to treat conditions like heart failure and Alzheimer's.

The team successfully modeled and obtained equations to explain how neurons respond to electrical stimuli from other nerves. This is a complicated process as the responses are non-linear. Then they went on to design silicon chips that precisely imitated real, living neurons and responded to a vast series of stimulations. 

The research team accurately duplicated the entire dynamics of hippocampal neurons and respiratory neurons in rats. This was performed under a broad range of stimuli. 

"Until now, neurons have been like black boxes, but we have managed to open the black box and peer inside," research lead Alain Nogaret was quoted as saying to the press. "Our work is paradigm-changing because it provides a robust method to reproduce the electrical properties of real neurons in minute detail,” he added.

How will artificial neurons help fight different health conditions?

It is being said that these artificial neurons will behave like the real thing, meaning that they will replicate what nerve cells do naturally. Neurons carry nerve signals from the brain to the rest of the body. The neurons in people who have dementia generally decay or die. That is where these artificial neurons could help replace those decaying neurons and potentially cure or bring some relief to those patients. 

Artificial neurons will have the ability to repair the infected bio-circuits by duplicating their healthy function and responding to biological feedback to revive bodily functions. 

For instance, in some cases of heart failure, the neurons in the human brain fail to respond to the feedback from the nervous system. The heart thus doesn’t receive the proper signals from the nervous system and doesn’t pump the way it should. The artificial neurons’ ability to replicate healthy functions of the bio-circuit will help in transferring feedback to the nervous system, in this case, and respond in a way as when this brain to heart connection was healthy.

The same will also apply in case of a spinal cord injury where the neurons' processes have been cut off, and the artificial neurons will be able to reconnect the neural pathways in the place of injury.

How feasible are these artificial neurons?

The researchers are now working on developing smart pacemakers which, with the help of these artificial neurons, will help in stirring the heart into action. Basically, pacemakers will use the artificial neurons to react to the immediate pressure being put on the heart. 

At present, the focus of the researchers is on heart failure as they believe that this new technology will offer significant improvements in the life of heart patients.

"Beyond heart failure any neurodegenerative disease or disease of ion channels would naturally benefit from artificial neurons. Seizures, Alzheimer's disease, Parkinson's disease are diseases that come to mind and where there is a need for novel solutions in the medical community,” they added.
Interestingly, these chips require only  140 nanoWatts of power - that's only one billionth of the power of a microprocessor which makes them highly convenient for implants. 
To know more about artificial neurons and how they may help heart attack patients, watch the video below.

The future?
This could be a revolutionary step in modern science and medical devices. It also opens up various horizons for people who suffer from neurological ailments and particularly those who have suffered from heart failure. Here is hoping that this would eventually genuinely help in making life easier for heart attack patients and others with degenerative diseases.

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Scientists revive brain funciton in dead pigs

Scientists have managed to restore cell function in the brains of pigs hours after they died, in a breakthrough that experts said threw into question the very notion of what makes animals of even humans--alive.

Authors said their research could one day be used to help treat victims of heart attacks and strokes and unravel the mysteries of brain trauma.

In human and large mammal brains, cells crucial for neural function begin to degrade as soon as blood supply is cut- a process long considered to be irreversible.

But the findings of the trial, show that the brains of pigs can have their blood flow and cell function restored even hours after death.

The team used the brains of 32 pigs that had been slaughtered for food and discarded, without blood or glucose flow for 4 hours each.

Then, using a tissue support system that pumps a liquid designed to mimic blood through organs, they rehydrated the brains for a further 6 hours.

Some brains received the patented life-support solution and others were given a control substance.
The results were astonishing: the brains that recived the artificial blood had basic cell function restored. Their blood vessel structure was revived, and the team even observed some localised processes- including in synapses and immune responses- flickering back to life.

Those that received the control solution turned within hours to what researchers described as something a bit like yoghurt.

I was tremendously surprised, a sresearcher and lead study author said.

We were surprised how well the structure was preserved. We found that cell death is reduced, which is very exciting and promising.

The main conceptual finding is this: cell death in the brain occurs across a longer time period than we previously thought , added the author.

The team stressed that they saw no higher level functional activity, such as electric signalling associated with consciousness in the revived brains.

That is a clinical sign that the brain is alive, and we never found it, he said. This is not a living brain, it is a cellularly active brain.

Had any such activity been detected, the team said they would have had to deliver anaesthetic to the brains to null any pain- despite then having been dead for hours.

If some activity shows up that indicated consciousness, we would have to stop the experiment, said a researcher.

This would be unique: inducing consciousness in an organ that's not connected to any living being.
The findings suggest that scientists may have under appreciated the brain's capacity for self-restoration after a patient is declared brain dead.

But for experts invited to comment on the study, it raised deeper philosophical and ethical questions.
Writing in a linked editorial, a Prof. of law and philosophy said that the study throws into question long-standing assumptions over what makes an animal or a human alive.

She said researchers had inadvertently created an ethical grey area where the pigs used were not alive, but not completely dead.

A Prof. of medical ethics said that the study could have vital implications for future brain research.
This research reminds us that death is less an event, and more of a process that occurs over time, he said.

Cells within the human organism may be alive for some period of time after the person has died.

A researcher said the team planned to use their support system on dead brains for longer periods of time in order to see how the cells react.

We could potentially get some insight into how these brains could be saved, he said.

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Scientists have managed to restore cell function in the brai ..

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CORIANDER- HEALTH BENEFITS

A little-known property of this commonly used spice is that it can help control modern day ailments like anorexia and bulimia.

It revives interest in food.

It is said to improve male sexual vitality and tone the uro-genital system in general.

In its raw form (as a leaf) it can be used a poultice to relieve pain and inflammation.

Coriander tea/ concoction is said to help control piles. It has a tremendous impact on the digestive tract and can control most problems related to it.

It can control weakness, fainting, relieve chronic headache (when applied as paste at the forehead) and relieve inflammatory conditions like ulcers and boils.

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Some Ways To Overcome Pain

Although pain is generally viewed as something negative, when seen through a prism of faith, it carries much deeper and complex meaning. It allows the sufferer to gain greater compassion, grow in strength and courage, and, ultimately, experience the joy of God’s ultimate love. Here are seven ways to find that joy in pain.

When the sensation of pain makes us feel older than our years, when life seems endlessly harsh, joy is present in things we might never have seen or imagined. A newborn baby, a just-opened flower, a day punctuated by self-discovery and hidden treasure – these and other examples of life’s ever-unfolding newness are all around us, inviting us to enjoy them and find joy in them.

The colours of pain might be the destructive red of searing loss, the inky black of an unknown future, or the lifeless grey of loneliness. It is hard to find comfort in them, but other colours can take their place. The bright gold of time with a good friend, the subtle pink of allowing yourself to rest, or the vibrant green of new hope found in advocating for yourself – all these and more can bring vitality and strength to your journey.

Inside of us, pain can hit hard and keep us down. But outside, there is much to uplift us. Music, nature, art, literature, journalism– these activities,or any other hobby that you've,  whether you do them or experience them, can provide counterbalance to the sadness and feeling of helplessness inside and inspire your spirit beyond them to find joy.

Unable to feel whole or of value? There is nothing like becoming someone else’s hero to revive your sense of worth. A day at an animal shelter, time spent with someone who is ill, an unexpected email to someone you know needs encouragement – no good gesture is too small to make a difference to the world and that, in turn, comes back to you in the form of fulfilment and joy.

The medications, the doctor’s visits, the therapy, the waiting, the sleepless nights – life with pain can get very complicated and crowd out simpler, more positive moments. Find a simple, still corner in your day, a place and time where you can appreciate life as the gift that it is. Then, from this place of simplicity, bring your renewed spirit into the other, more challenging parts of your world.

DON"T LOSE YOUR CHILDHOOD INNOCENCE- Even children who are seriously ill have a way of finding delight, laughing, and playing. When we reach adulthood, we do not abandon our childhood innocence and trust, but we might not acknowledge its presence when pain interferes. Invite whimsy, play, and humour into your life and let it rekindle your inner child – and the joy that resides in your heart.





ps- this is only for information, always consult you physician before having any particular food/ medication/exercise/other remedies.

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http://gseasyrecipes.blogspot.com/

for info about knee replacement, you can view my blog-

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I've not given details about designs, but those interested are free to mail me for the same.

Brain temperature can now be measured non-invasively

The doctors suggest that an injured brain can be significantly warmer than the body.  

Researchers have developed a way to measure the brain’s precise temperature with a device only as thick as a poker-chip and which rests on a patient’s head, eliminating the necessity of insertion.

The doctors also suggest that an injured brain can be significantly warmer than the body, a finding critical to cooling therapies that reduce brain damage in everyone from elderly heart attack victims to hypoxic (lacking oxygen) newborns.

“This is the first time that anyone has presented data on the brain temperature of a human obtained non-invasively,” .

Hypoxic brain damage in infants occurs most often in full-term births when the child suffers oxygen loss either immediately before or during delivery.

Because of a quirk in the brain, a child can be revived but brain cells continue to die over several days, resulting in brain damage or death.

Doctors could do little to stop this progression - parents often watched helplessly as their sons and daughters literally died before their eyes.

A research team led by Professor Bass, who pioneered research on cooling therapy for hypoxic newborns, adapted an instrument that calculates temperatures by detecting microwave emissions produced by all human tissues.

Those microwaves pass unimpeded through the skull, like light passing through a sheet of glass. As tissue temperatures increase, the emissions grow more intense.