Friday, July 29, 2011

Pharyngeal Cancer- risk factors,


  • Age over 40
  • Male sex
  • Smoking
  • Chewing tobacco
  • Heavy alcohol use
  • Oral lichen planus (a chronic autoimmune disease manifesting as lacy white patches in the mouth or throat)
  • Human papillomavirus infection, especially in oropharyngeal cancers
  • Epstein-Barr virus infection, especially in nasopharyngeal cancers
  • Southern Chinese or South Asian ancestry, primarily in nasopharyngeal cancers
  • Diet low in fruits and vegetables/antioxidants (oropharyngeal/hypopharyngeal)
  • Plummer-Vinson syndrome (hypopharyngeal cancer)
  • Drinking maté, a stimulant drink common in South America (oropharyngeal cancer)
  • Leukoplakia (white patches in the mouth or throat) (oropharyngeal cancer)
  • Erythroplakia (red patches in the mouth or throat) (oropharyngeal cancer)
  • Chewing betel quid, a stimulant commonly used in parts of Asia (oropharyngeal cancer)

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Pharyngeal Cancer Symptoms

Pharyngeal cancer may not have symptoms in the early stages. When present, symptoms may include the following:

Nasopharyngeal Cancer

  • A lump in the nose or neck
  • Sore throat
  • Trouble breathing or speaking
  • Nosebleeds
  • Trouble hearing
  • Pain or ringing in the ears
  • Headaches
  • Oropharyngeal Cancer 
    • A sore throat that does not go away
    • A lump in the back of the mouth, throat or neck
    • Dull pain behind the breastbone
    • Cough
    • Trouble swallowing
    • Unexplained weight loss
    • Ear pain
    • Change in voice
    • Leukoplakia (white patches in the oropharynx)
    • Erythroplakia (reddish patches in the oropharynx)
    Hypopharyngeal Cancer 
    • A sore throat that does not go away
    • Ear pain
    • A lump in the neck
    • Painful or difficult swallowing
    • A change in voice

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Pharyngeal Cancer Diagnosis


A variety of methods is used to diagnose pharyngeal cancers. They include:
  • Physical exam and history
  • Head, neck and chest X-rays
  • MRI (magnetic resonance imaging): A procedure that uses a magnet, radio waves and a computer to make a series of detailed pictures of areas inside the body. This procedure is also called nuclear MRI, or NMRI.
  • CT (computed tomography) scan: A procedure that makes a series of detailed pictures of areas inside the body, taken from different angles. The pictures are made by a computer linked to an X-ray machine. Contrast medium (a dye injected into a vein or swallowed to help the organs or tissues show up more clearly) is generally not used when imaging the sinonasal area. This procedure is also called computerized tomography or computerized axial tomography.
  • Positron emission tomography (PET) scan: A procedure to find malignant tumor cells in the body. A small amount of radioactive glucose derivative fluorodeoxyglucose (FDG) is injected into a vein. The PET scanner rotates around the body and generates a picture of where glucose is being used in the body. Malignant tumor cells show up brighter in the picture because they are more active and take up more FDG than normal cells do. PET scans may be used to find nasopharyngeal cancers that have spread to the bone. It has also been used to find distant metastases (primarily to the lungs) in hypopharyngeal cancers.
  • Bone scan: A procedure to check if there are rapidly dividing cells, such as cancer cells, in the bone. A very small amount of radioactive material is injected into a vein and travels through the bloodstream. The radioactive material collects in the bones and is detected by a scanner.
  • Endoscopy: A procedure to look at organs and tissues inside the body to check for abnormal areas. An endoscope is inserted through the patient’s nose or mouth to look at areas in the throat that cannot be seen during a physical exam of the throat. An endoscope is a thin, tube-like instrument with a light and a lens for viewing. It may also have a tool to remove tissue or lymph node samples for biopsy.
    • Biopsy: The removal of suspect tissue for analysis. A pathologist views the tissue under a microscope to look for cancer cells. This test is necessary to establish three things:  1) whether the tumor is benign or malignant, 2) what type of cell the tumor originated from and 3) what grade, or level of differentiation, the tumor cells display.
    • Human papillomavirus (HPV) test: Testing the blood or a biopsy sample for HPV may help reveal information about the cancer involved and provide treatment guidance.
    For nasopharyngeal cancer: 
    • Nasoscopy: A procedure to look inside the nose for abnormal areas. A nasoscope is inserted into the nose. A nasoscope is a thin, tube-like instrument with a light and a lens for viewing. It may also have a tool to remove tissue samples for biopsy.
    • Neurological exam: A series of questions and tests to check the brain, spinal cord and nerve function. The exam checks a person’s mental status, coordination and ability to walk normally, and how well the muscles, senses and reflexes work.
    • Epstein-Barr virus (EBV) test: Testing the blood or a biopsy sample for EBV may help reveal information about the specific type of nasopharyngeal cancer involved and provide treatment guidance.
    For hypopharyngeal cancer: 
    • Barium esophagogram: An X-ray of the esophagus. The patient drinks a liquid that contains barium (a silver-white metallic compound). The liquid coats the esophagus and X-rays are taken.
    • Esophagoscopy: A procedure to look inside the esophagus to check for abnormal areas. An esophagoscope (a thin, lighted tube) is inserted through the mouth or nose and down the throat into the esophagus. Tissue samples may be taken for biopsy.
    • Bronchoscopy: A procedure to look inside the trachea and large airways in the lung for abnormal areas. A bronchoscope (a thin, lighted tube) is inserted through the nose or mouth into the trachea and lungs. Tissue samples may be taken for biopsy.

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Pharyngeal (Throat) Cancer & its types


The term “throat cancer” can refer to either cancer of the pharynx or the larynx. Pharyngeal cancer occurs when cells in the pharynx become malignant and aggregate to form a tumor.
About the Pharynx

The pharynx is typically divided into three parts:
  • Nasopharynx – the upper part of the throat located behind the nasal cavity and above the soft palate.
  • Oropharynx – the middle part of the throat that lies behind the oral cavity.  This is the part of the throat you can readily see when looking in the mirror. It allows food and fluids to pass from the mouth to the esophagus and air to flow into the lungs via the trachea.
  • Hypopharynx (sometimes called laryngopharynx) – the lower part of throat located behind the oropharnyx and adjacent to the larynx. It helps in swallowing and prevents aspiration.
All parts of the pharynx, along with the nasal cavity and paranasal sinuses, act as resonating chambers for sounds produced by the vocal cords in the larynx.
Nasopharyngeal Cancer
Nasopharyngeal cancer is different from other pharyngeal cancers in several significant ways:
  • It is much more prevalent within Asian and Southeast Asian populations, with highest incidence in Southern China (Guangdong Province) and Taiwan
  • It is strongly correlated with infection by Epstein-Barr virus (EBV)
  • Some types are highly radiosensitive, and radiotherapy is the preferred treatment
Most nasopharyngeal cancers are squamous cell carcinomas. These can be subdivided into several forms, which vary in terms of cellular differentiation:
  • Keratinizing
  • Well-differentiated cells that produce keratin
    • More common in the United States; less common in Asia
    • Less associated with EBV infection
    • May be associated with traditional risk factors of head and neck squamous cell carcinoma such as tobacco use
    • Less radiosensitive and more radioresistant
    • Tends not to metastasize to distant sites, but is frequently locally invasive
      • Non-keratinizing (cells do not produce keratin)
        • Moderately-differentiated subtype
          • Tends to metastasize to regional lymph nodes
          • Variable radiosensitivity
          • Often linked to EBV infection
        • Undifferentiated subtype
          • Often occurs in conjunction with high numbers of lymphocytes, and may also be called lymphoepithelioma
          • More common in Asia
          • Most often associated with EBV infection
          • Tends to metastasize to regional lymph nodes
          • Very radiosensitive
      Oropharyngeal Cancer

      Like other pharyngeal cancers, most oropharyngeal cancers are squamous cell carcinomas. Sites within the oropharynx that may develop cancer are:
      • Base of the tongue
      • Tonsillar region (the most common site for primary cancers of the oropharynx)
      • Soft palate, which includes the uvula
      • Pharyngeal walls
      • Risk Factors for Oropharyngeal Cancer
        • Tobacco (both chewed and smoked) is strongly linked to developing oropharyngeal cancer.
        • Poor nutrition, specifically a diet low in fruits and vegetables that result in few dietary antioxidants
        • Heavy alcohol consumption
        • Eastern Asian decent
        • HPV (human papillomavirus) has been implicated as a major factor in the disease, with transmission occurring through oral sex.
        Hypopharyngeal Cancers
        Hypopharyngeal cancers are the least common type of pharyngeal cancer. Again, almost all cancers of this type are squamous cell carcinomas.
        Risk Factors for Hypopharynceal Cancer
        • Excessive drinking
        • Smoking
        • Poor nutrition, specifically a diet low in fruits and vegetables that result in few dietary antioxidants
        • Male gender
        • HPV (human papillomavirus). While HPV is much more prevalent in oropharyngeal cancers, it has been found in some hypopharyngeal cancer patients. Its significance in the development of this cancer is unknown.

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Monday, July 25, 2011

How to strengthen your knee



Add strength by walking backwards
When walking down the stairs becomes more painful than walking up, you know you better tend to your knee problem. Luckily, our friend a sports science professor in South Africa, told us about an odd but effective way to ward off the ache: Walk backwards. Moving backward recruits more muscles in the thighs than moving forward. Strong hamstrings and quads keep the knee joint stable and pain-free. Watch how we do it:
Step 1: Start on treadmill, take it slow. Walk at 1.5 to 2 mph for 1 minute. Turn around and walk forward for 2 minutes. Continue alternating for 30 minutes. If you feel unsteady, grab the handlebars or turn back around.
Step 2: Increase speed, take it outside. Once you’re comfortable at the original pace, up your speed by .5 mph every week, until you reach 3.5 or 4 mph. Try practicing your backwards walking at the park or track, too.
Step 3: Ignore strange looks at gym or park. Tell any gawkers that you're training for a new Olympic event !

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Not all chest pain will be heart attack !

Since I already had an heart attack, I was worried when I again had chest pain with pain from my left shoulder radiating down to my arm. So, an ECG & ECHO was done, as just 2 months ago, I had fluid around my heart which was drained out through a delicate & dangerous procedure. So, the pain was worrying me, my family & the doctors too. Luckily, this time, as the ECG & ECHO were normal, the cardiologist suggested that I'd see an gastroenterologist. Knowing that I'm a thyroid cancer survivor & now on steroids, the doctor & my daughter, who is also a doctor, thought that it may be due to hernia or ulcer. So, an endoscopy was done, which showed that I did have some ulcers in my food pipe along with re-flux problems. So, now with some medications, 30 minutes before breakfast & dinner, I'm slightly feeling better.

For those with similar problems, some simple precaution that one can take is to cut down on caffeine intake, avoid citrus fruits, have at least 3 hours gap between your meal & sleeping time, as going to bed with full stomach can cause severe pain. keep your head elevated while sleeping. don't get tensed, as that also leads to more ulcers !

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How to protect yourself from bug, snake, spider & other skin problems


JeJellyfish Stings

A jellyfish sting may cause intense pain, rash and welts, and may progress to vomiting and muscle spasms. Severe reactions can cause difficulty breathing, coma, and death. Box jellyfish stings require immediate medical care. Flood the area with vinegar and keep still until help arrives. For other jellyfish stings, soak the area in vinegar.


Stingray Sting
Sting symptoms can include sharp pain, bleeding from the wound, vomiting, chills, and paralysis. Death may even occur. Most stingray injuries require immediate medical care. If help isn’t readily available, immerse the injured area in hot water, remove the stingers, and scrub the wound with soap and fresh water. Apply pressure to stop the bleeding.

Mosquito Bites
Mosquitoes aren't just annoying; scratching a bite can cause a skin infection, too. Mosquitoes can also carry West Nile virus, dengue fever, and other diseases. To protect yourself from mosquitoes, apply insect repellent and cover up when you go outdoors, use door and window screens, and get rid of standing water in your yard, which is where mosquitoes lay their eggs.

Ticks
If you enjoy the outdoors, be careful of ticks -- they can attach to you as you brush past grass and plants. Ticks don't always carry diseases, and most bites aren’t serious. But they can carry diseases including Lyme disease and Rocky Mountain spotted fever. A bite can also trigger an allergic reaction. Be sure to remove a tick properly. To prevent tick bites, keep arms, legs, and head covered in grassy areas and use tick repellant.

Bee Stings
Most reactions to bee stings are mild, causing minor swelling, pain, and itching. Severe allergic reactions occur in some people, with symptoms including hives, swelling of the mouth or throat, and difficulty breathing. If you have a severe anaphylactic reaction, lie down and remove the stinger.  Give yourself an epinephrine injection, if you have access one, and get immediate medical care. If you don't have an allergic reaction, remove the stinger, clean the sting site, apply ice, and take an oral antihistamine for itching.


Chiggers
Chiggers are tiny mites found in tall grass or weeds. They attach to the skin by inserting tiny mouth parts to penetrate and liquefy the skin cells on which they feed. Their bites are painless. But after a few days of being attached to the skin, chiggers fall off – leaving very itchy red welts. Over-the-counter products can help relieve the itch, but see a doctor if your skin appears infected or the welts seem to be spreading.


Flip-Flop Hazards
They may be fun and fashionable, but flip-flops offer little protection against stubbed toes, glass cuts, puncture wounds, or having a heavy object smash your foot. Another danger: insect and snake bites. Emergency room physicians on both sides of the country report seeing adults and children with snake bites to the feet while wearing flip-flops or sandals. Consider wearing close-toed shoes that offer better protection this summer.


Poisonous Snake Bites
Bite symptoms may include severe burning pain at the bite site, swelling that spreads out from the bite, weakness, trouble breathing, and changes in heart rate. Bite severity depends on many factors, including the amount of venom injected, bite location, and a person’s age and health. Seek immediate medical care if you think you’ve been bitten by a poisonous snake.


Nonpoisonous Snake Bites
A bite may leave fang marks or other puncture wounds that can be treated at home to relieve symptoms and prevent infection. However, large nonpoisonous snake bites, such as those from pythons or boa constrictors, can cause injury to skin, joints, bones, and muscles because of the force of the bite. See a doctor for these bites.


Black Widow Spiders
Wood piles and tree stumps -- that's where poisonous female black widows hide. Her bite may cause sharp, shooting pain up the limb, but it may also be painless. Look for one or two red fang marks, redness, tenderness, and a nodule at the bite site. Muscle cramps, nausea, vomiting, seizure, and rise in blood pressure may follow soon after a bite. Seek medical care if bitten.


Brown Recluse Spiders
Hiding in attics and closets – in Midwestern and South central states – that's where you'll find these spiders. They range in color from yellowish-tan to dark brown, with darker legs. Their venom is extremely poisonous, and their bite can cause serious wounds and infection. The bite itself is often painless -- then skin reddens, turns white, develops a red "bull's-eye," blisters, and becomes painful. Bites warrant immediate medical care.


Burns from Fireworks
An estimated 9,200 people were treated in emergency rooms in 2006 for injuries related to fireworks. Most injuries involved the hands, eyes, head, face, and ears. Burns were the most common injury. Minor burns smaller than a person's palm can often be treated at home. Run it under cool water, then cover with a clean, dry cloth. Larger burns, and ones to the hands, feet, face, genitals, and major joints usually require emergency care.


Skin Cancer
Skin cancer is the most prevalent of all cancers in the U.S. An uncontrolled growth of abnormal skin cells, it results in tumors that are benign or malignant. There are three main types of skin cancer: basal cell carcinoma, squamous cell carcinoma, and melanoma. Consult a doctor if a mole or spot changes in size, shape, or color, has irregular edges, is more than one color, is asymmetrical, or itches, oozes, or bleeds.


Heat Rash
The result of blocked sweat ducts, heat rash looks like small pinkish pimples and is usually found on body areas covered by clothing. Most common in children, it may also affect adults in hot, humid climates. Most rashes heal on their own. To alleviate symptoms, apply cold compresses or take a cool bath. Air dry and avoid lotions. If baby's skin is irritable to the touch, ask your doctor about using calamine or hydrocortisone cream.


Sunburn

Too much exposure to the sun's UV rays can result in the redness and pain of sunburn. Sunburn usually appears within hours after sun exposure and may take weeks to fade. Pain relievers, cold compresses, aloe, hydrocortisone, or moisturizing creams may ease discomfort. Second-degree sunburn -- characterized by redness, swelling, and blistering – is usually more painful and takes longer to heal. See a doctor if you have a blistered sunburn.ll


For more infor kindly read=

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Fighting cancer with colorful foods


No single food can reduce your risk of cancer, but the right combination of foods may help make a difference. At mealtimes, strike a balance of at least 2/3 plant-based foods and no more than 1/3 animal protein. 

Fruits and vegetables are rich in cancer-fighting nutrients - and the more color, the more nutrients they contain. These foods can help lower your risk in a second way, too, when they help you reach and maintain a healthy body weight.

Cut down your weight as carrying extra pounds increases the risk for multiple cancers, including colon, esophagus, and kidney cancers. Aim for at least five servings a day, prepared in a healthy way.

Folate is an important B vitamin that may help protect against cancers of the colon, rectum, and breast.  You can find it in abundance on the breakfast table. Fortified breakfast cereals and whole wheat products are good sources of folate. So are orange juice, melons, and strawberries.
Other good sources of folate are asparagus and eggs. You can also find it in chicken liver, beans, sunflower seeds, and leafy green vegetables like spinach or romaine lettuce. The best way to get folate is not from a pill, but by eating enough fruits, vegetables, and enriched grain products.



Cutting back on processed meats like bologna, ham, and hot dogs may help lower your risk of colorectal and stomach cancers. Also, eating meats that have been preserved by smoking or with salt raises your exposure to agents that can potentially cause cancer.

Tomatoes
Whether it's the lycopene -- the pigment that gives tomatoes their red color -- or something else isn't clear. But some studies have linked eating tomatoes to reduced risk of several types of cancer, including prostate cancer. Studies also suggest that processed tomato products such as juice, sauce, or paste increase the cancer-fighting potential.


Tea
green tea, may be a strong cancer fighter. In laboratory studies, green tea has slowed or prevented the development of cancer in colon, liver, breast, and prostate cells. It also had a similar effect in lung tissue and skin. And in some longer term studies, tea was associated with lower risks for bladder, stomach, and pancreatic cancers.


Grapes and Cancer

Grapes and grape juice, especially purple and red grapes, contain resveratrol. Resveratrol has strong antioxidant and anti-inflammatory properties. In laboratory studies, it has prevented the kind of damage that can trigger the cancer process in cells. 

Alcohol not good for cancer

Cancers of the mouth, throat, larynx, esophagus, liver, and breast are all linked with drinking alcohol. Alcohol may also raise the risk for cancer of the colon and rectum.  

Water and Other Fluids Can Protect

Water not only quenches your thirst, but may protect you against bladder cancer. The lower risk comes from water diluting concentrations of potential cancer-causing agents in the bladder. Also, drinking more fluids causes you to urinate more frequently. That lessens the amount of time those agents stay in contact with the bladder lining.

The Mighty Bean
Beans  contain several potent phytochemicals that may protect the body's cells against damage that can lead to cancer. In the lab these substances slowed tumor growth and prevented tumors from releasing substances that damage nearby cells.

Cabbage Family vs. Cancer
Cruciferous vegetables include broccoli, cauliflower, cabbage, Brussels sprouts, bok choy, and kale. These members of the cabbage family make an excellent stir fry and can really liven up a salad. But most importantly, components in these vegetables may help your body defend against cancers such as colon, breast, lung, and cervix.

Dark Green Leafy Vegetables







 
Dark green leafy vegetables such as mustard greens, lettuce, kale, chicory, spinach, and chard have an abundance of fiber, folate, and carotenoids. These nutrients may help protect against cancer of the mouth, larynx, pancreas, lung, skin, and stomach.

Turmeric

Curcumin is the main ingredient in the Indian spice turmeric and a potential cancer fighter. Lab studies show it can suppress the transformation, proliferation, and invasion of cancerous cells for a wide array of cancers.

Berries & cancer

Strawberries and raspberries have a phytochemical called ellagic acid. This powerful antioxidant may actually fight cancer in several ways at once, including deactivating certain cancer causing substances and slowing the growth of cancer cells
The potent antioxidents in blueberries may have wide value in supporting our health, starting with cancer. Antioxidants fight cancer by ridding the body of free radicals before they can do their damage to cells. Try topping oatmeal, cold cereal, yogurt, even salad with blueberries to boost your intake of these healthful berries.

Supplements
Vitamins may help protect against cancer. But that's when you get them naturally from food. like nuts, fruits, and green leafy vegetables is vastly superior to getting them from supplements. Eating a healthy diet is best.


for more info kindly read-
http://www.webmd.com/cancer/slideshow-cancer-fighting-foods








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