Regular use of aspirin bad for uterine cancer patients

Regular use of over-the-counter non-steroidal inflammatory drugs (NSAIDs) such as aspirin and ibuprofen is associated with an increased risk of dying in patients diagnosed with a type of uterine cancer.

"There is a increasing evidence that chronic inflammation is involved in endometrial cancer and progression and recent data suggests that inhibition of inflammation through NSAID use plays a role," said co-lead author of the study Theodore Brasky from Ohio State University in the US.

"Our finding was surprising because it goes against previous studies that suggest NSAIDs can be used to reduce inflammation and reduce the risk of developing or dying from certain cancers, like colorectal cancer," Brasky said.

In the study involving more than 4,000 patients, the researchers found that regular NSAID use was associated with a 66 per cent increased risk of dying from endometrial cancer among women with Type-1 endometrial cancers, a typically less-aggressive form of the disease.

The association was statistically significant among patients who reported past or current NSAID use at the time of diagnosis, but it was strongest among patients who had used them for more than 10 years in the past but had ceased use prior to diagnosis.

Use of NSAIDs was not associated with mortality from typically more aggressive form of the cancer, according to the study published in the Journal of the National Cancer Institute.

This is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.     

https://gscrochetdesigns.blogspot.com. one can see my crochet creations  
https://gseasyrecipes.blogspot.com. feel free to view for easy, simple and healthy recipes    
https://kneereplacement-stickclub.blogspot.com. for info on knee replacement 

Painkillers, or Plain Old Killers?

Painkillers are incredibly accessible, requiring no prescription from a medical professional and providing a reprieve from all sorts of fevers, pains and inflammation. They are so available, that the average person takes 373 painkillers in a single year, and it has been assessed that 1 in 20 people takes as many 6 such pills when ill. Considering how pervasive and easy to acquire they are, they must be safe, right? Not quite.

 

Non-steroidal anti-inflammation drugs (NSAIDs) like aspirin and ibuprofen (such as Advil) are among the most popular painkillers, due to their potency and ability to treat inflammation. They are also highly preferable to corticosteroids, the other major anti-inflammation measure, which require a prescription and can cause a slew of severe adverse side-effects.

But just because they’re preferable to a bad drug, doesn’t make them good.

A 2017 study conducted by a team of  medical experts attempted to gauge the impact NSAIDs may have on an increased risk of heart attack. Their findings were alarming, to say the least.

By cross-referencing previous studies encompassing a group of 446,763 individuals, they found that taking NSAIDs over a period of one day to a week was associated with a dramatic risk increase of heart attack, with ibuprofen causing a 48% hike in risk of myocardial infarction. Rofecoxib, another NSAID that had an even more drastic impact at 58%, had been recalled in 2004, though it is now being considered to return to the market as a specialized treatment for hemophiliacs.

Higher dosages of NSAIDs was associated with an even greater risk, though the period of intake did not seem to effect the odds.

Other severe side-effects associated with NSAIDs are gastrointestinal bleeding and ulcers, as well as kidney failure.

Ibuprofen has also been connected with decreased fertility in males, and other NSAIDs such as Voltaren and Arcoxia seemed to have a similar effect on female ovulation.

Between all of these side effects, it might be incumbent upon us to change our lifestyles in such a way that we won’t be so dependent on painkillers to begin with. Change your diet to reduce inflammation, and attempt to change your schedule to accommodate more sleep and less physical and mental stress.

THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.                                    PS- THOSE INTERESTED IN RECIPES ARE FREE TO  VIEW MY BLOG-                                                                                           https://gseasyrecipes.blogspot.com/                                                                                                                                                         FOR INFO ABOUT KNEE REPLACEMENT, YOU CAN VIEW MY BLOG-                                                  https:// kneereplacement-stickclub.blogspot.com/           

                   FOR CROCHET DESIGNS                                                                                                                                                                                                  https://gscrochetdesigns.blogspot.com

 

 

Ways To Manage Hand Pain

The human hand is made up of 27 bones and a number of tendons and ligaments. An injury to any one of these bones or a disease that affects the bones and ligaments can make you experience excruciating pain in your hands. This pain can affect your ability to perform simple day to day tasks like holding a spoon or writing. Some common reasons your hand may pain are muscle strains, fractures, arthritis and carpal tunnel syndrome. Apart from pain relieving medication, there are a number of ways you can deal with this pain.

1. Hot and cold compresses: Hot and cold therapy is ideal for any type of muscle or ligament injury. A cold compress helps in reducing the pain and inflammation by constricting blood vessels and numbing the area. On the other hand, a hot compress dilates blood vessels and increases the flow of blood and oxygen to the affected area. Ideally, the two should be used alternatively for 10 to 20 minutes each. A bag of frozen vegetables or ice wrapped in a towel makes an easy cold compress. To treat your hand with heat, use a moist heating pad or a hot water bottle. You could also dip your hands in warm water.
2. Massage: A massage is a great way to treat hand pain that results from carpal tunnel syndrome. If the exact cause of pain is not known, massage the entire hand, wrist and forearm. A massage enhances blood flow to the area and hence improves flexibility and opens locked tendons. Using a few drops of essential oils such as lavender or  rosemary can also aid in relieving hand pain.
3. Hand exercises: If your work involves repetitive actions like typing, knitting or embroidery, the muscles in your hand can get locked into position thereby, causing pain and discomfort. To relieve this it is important to take a break from this repetitive exercise every hour and flex your hand. Try bending your fingers forwards and backwards and rotating your wrists in both directions to ensure that your joints remain smooth.
4. Epsom salt water bath: For instant relief from intense hand pain, soak your hands in a bath made of hot water and Epsom salts for 10 to 20 minutes. Follow this by wrapping your hands in a warm, wet washcloth and applying gentle pressure over the hand for 5-10 minutes. You should instantly feel relief from the pain and experience increased the flexibility of hand.

5. Injections :An injection of a corticosteroid into a joint can reduce inflammation. "The relief it provides can last up to a year," says Dr. For some people the amount of relief diminishes with subsequent injections.

   6. NSAIDs - A nonsteroidal anti-inflammatory drug (NSAID) helps relieve hand pain by blocking enzymes that produce pain and swelling, but Dr.  says it's not effective for carpal tunnel syndrome. Long-term use of oral NSAIDs such as ibuprofen (Advil, Motrin) are linked to ulcers, stomach bleeding, liver damage, and increased risk of heart attacks. Topical NSAIDs, such as diclofenac (Voltaren), may pose less risk.

   7. Splinting :A splint stabilizes the position of your fingers, thumb, or wrist. "Wear a splint for a few weeks if arthritis flares, so the inflammation can settle down," says Dr.             

   THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.                                                                                                                                                                                                                                                   PS- THOSE INTERESTED IN RECIPES ARE FREE TO  VIEW MY BLOG-                                                                                           https://gseasyrecipes.blogspot.com/  
   FOR INFO ABOUT KNEE REPLACEMENT, YOU CAN VIEW MY BLOG-                                                                                                             https:// kneereplacement-stickclub.blogspot.com/                              
   

   FOR CROCHET DESIGNS                                                                                                                                                                                                                                 https://gscrochetdesigns.blogspot.com

Statins could increase your daily fat intake

The Indian Express reported a study which revealed that individuals taking statins (cholesterol-lowering drugs) tend to gradually raise their consumption of fat and calories.
 
It’s a 12-year study on statin use involving 27,886 men and women participating in a 24-hour dietary recall interview for cholesterol levels and body mass index. It was found that statin use increased from 7.5 per cent in 1999 to 16.5 per cent in 2010 in the group of participants. The cholesterol levels reduced in statin users but their daily calorie intake raised by 9 per cent, and fat consumption increased by 14.4 per cent. Non-users did not show any significant changes in either measure. Body mass index raised in statin users by 1.3 compared with an increase of 0.4 in the non-user group. The effect was seen despite control over factors like age, race, education and conditions like of diabetes and high cholesterol. (Read: Is it necessary to take statins for preventing heart diseases?)

How do statins work? How they prevent heart disease?
‘Cholesterol is a type of fat made by our body. It’s essential for good health and is found in every cell in the body. However, if you have too much ‘bad’ cholesterol (low-density lipoprotein or LDL) in your blood, it can cause fatty deposits to build up on the walls of your arteries. This is known as atherosclerosis – a condition that narrows your arteries.

Statins work by reducing the amount of LDL cholesterol your body makes. They do this by blocking an enzyme in your liver needed to produce cholesterol. This slows down the production of cholesterol by your liver. By reducing cholesterol, statins can help to reduce your risk of having a heart attack, stroke or developing peripheral arterial disease.

There is some evidence to suggest that statins may also work in a number of other ways to help reduce your risk of cardiovascular disease.

One promising benefit of statins appears to be their anti-inflammatory properties, which help stabilise the lining of blood vessels. This has potentially far-reaching effects, from the brain and heart to blood vessels and organs throughout the body.

What precautions should a person take while on statins?
‘Too much of a good thing can be bad, but too little of a bad thing can be even worse. So, first of all, patients on statins should have regular blood tests to monitor their lipid levels,’ says Dr Bela Sharma, senior consultant, internal medicine, FMRI.
Other important things to remember:

• Adherence to prescribed medication dosage is extremely essential.  
• Avoiding drug interactions, mainly with drugs (erythromycin, simvastatin, cyclosporine) that block liver enzymes.
• In case you experience any adverse side-effect, consult your doctor immediately. 
•  
•  
  

  PS- THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.

  PS- THOSE INTERESTED IN RECIPES ARE FREE TO VIEW MY BLOG-

  HTTP:GSEASYRECIPES.BLOGSPOT.COM/

  FOR INFO ABOUT KNEE REPLACEMENT, YOU CAN VIEW MY BLOG-

  HTTP://KNEE REPLACEMENT-STICK CLUB.BLOGSPOT.COM/
  
  FOR CROCHET DESIGNS
  
  HTTP://MY CROCHET CREATIONS.BLOGSPOT.COM

Knee and Hip Replacements Linked to Heart Attack

 People over age 60 who have surgery to replace a worn-out hip or knee have a significantly higher risk of having a heart attack after their surgeries, a large new study shows.

Researchers found that one in 200 people who had a hip  replacement had a heart attack within six weeks of surgery. The study also found that one in 500 people who had a knee replacement had a heart attack within six weeks of surgery.

Compared to adults of the same age and sex who didn't have joint replacement surgeries, people who had hip replacements were 25 times more likely to have heart attacks, within two weeks of their procedures. People who had knee replacements were about 30 times more likely to suffer heart attacks in that same time period.

Those risks remained even after researchers adjusted their data to account for a variety of things that can increase the risk of heart attacks, such as:

• age
• sex
• socioeconomic status
• use of certain medications known to increase the risk of heart attacks, such as non-steroidal anti-inflammatory drugs 

To be sure, surgery is stressful. Previous studies have found that having surgery of any kind raises the risk of having a heart attack. That's especially the case for adults who are over age 60 with a history of heart disease.

Even thinking about surgery has been shown to increase the risk of a heart attack, notes ,  an anaesthesiologist.