Friday, October 18, 2019

How to Remove Skin Tags Safely with Iodine

At first, to define skin tags; skin tags are small, skin-coloured growths which hang off the skin. 

Sometimes, they are also called soft wards or soft fibromas. Almost every one of us has these skin tags. Although these growths do not cause medical complications, they are annoying and irritating.

Is Iodine Good for skin tags?
For a more extended period, it has been debated if iodine is good for skin tags. It can be said that iodine is an adequate and secure remedy to dispose of skin tags. The instructions of this remedy say that you should apply it to the area which is affected twice in a day for some time.

How to Use Iodine for Skin Tag Removal
There are a lot of different approaches on how to remove skin tags. Of course, some of them are more effective than others. Consult a specialist to choose the best and the most effective remedy for you. Iodine is considered to be one of the most effective solutions. Only after a few days of using it, the skin tags are removed.

How to remove skin tags with iodine
What you need:
For this treatment you do not need many things; in fact, all you need is:
  • Iodine tincture,
  • a dropper for applying iodine on the skin and
  • Roll of bandage or duct tape to seal the tag.
It is worth to be mentioned that this product has antiseptic properties.

How to Apply Iodine on Your Skin Tag:
Be aware that you should not apply iodine on your healthy skin. In order to avoid this, you can rub a coconut oil barrier into your healthy skin. Thus, the area that is surrounded by this growth stays clean of iodine.
After this, fill the dropper with the iodine. Next, apply it on your skin tag and seal the growth with the roll of bandage.
 It is recommended to do this twice a day until the skin tag is removed.

Does Iodine Work on Skin Tags?
The chemical element iodine kills germs other kinds of growths. When it is applied to the area which is affected it causes the skin cells to get off safely.
When to Apply: To have better results, you should apply iodine twice a day on the area which is affected.

Skin tags are benign, noncancerous tumours of the skin; they are harmless and don’t cause pain. However, patients should not pull off these tags because they can infect or irritate the area. If you try to pull it off, you will cause much bleeding, and you may feel pain and discomfort and even leave yourself with a scar. If you are looking for a safe remedy, iodine is the best choice for you. You will see the first results only after a few days of using it.

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Thursday, April 06, 2017

Personalised therapies for prostate cancer


Biomarker could lead to personalized therapies for prostate cancer, according to a recent study.

In 2016, more than 181,000 new cases of prostate cancer were reported in the U.S., according to the American  Cancer Society. The prostate-specific antigen (PSA) test is one of the earliest ways clinicians can detect prostate cancers in their patients. Sometimes, a high PSA level may be a sign of benign conditions such as inflammation; therefore, more reliable tests are under investigation to help urologists diagnose and treat the disease in an aging population. 

Now, researchers at the University of Missouri have explored how a specific protein's status may allow clinicians to better identify prostate cancer progression while helping them to make rational decisions in treating the disease.

"Our research is focused on finding genetic biomarkers that help identify prostate  cancer patients at risk for more aggressive diseases as well as candidates who may have successful drug treatment or response," said principal investigator Senthil Kumar.
The team identified that the testis-specific Y-like protein (TSPYL5) varied between normal patients and tumor tissues with different Gleason scores (which can range from 2-10), a tool used by pathologists and urologists to categorize the stages of cancer. This score can categorize patients based on disease aggressiveness, helping to define subsequent treatment options.

The multidisciplinary team, including members from the MU School of Medicine, collected human prostate cancer samples at various stages of the disease as described by the Gleason score.
The researchers discovered that TSPYL5 was present in the tissues with Gleason score of 7, but was diminished or absent in some patients with Gleason score of 7 and above, which could predict a more aggressive course of prostate  cancer progression. Moreover, they identified that the presence of TSPYL5 could facilitate better drug response as tested in the prostate carcinoma cells.

"TSPYL5 testing could become one of the tools in our fight against prostate cancer," Kumar said. "The anticipation is that we can use this biomarker for patients before they undergo any unnecessary and invasive surgeries or drug therapy plans."

Kumar mentioned that this study needs to be conducted in large patient cohorts to further validate its potential for clinical translation. Studies along this line are in progress, Kumar added.
The study is published in BMC Cancer.

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Thursday, November 17, 2016

MORTON'S NEUROMA

Morton's neuroma, a benign nerve tumor, is linked to wearing high heels and shoes with tight toe boxes -- so women get it 8 to 10 times more often than men.
 
It's a thickening of the tissue around a nerve heading between the third and fourth toes. The shooting pain feels like stepping on a hard kernel of corn.
 
Another surprising cause: positioning your toes abnormally. Golfers, who twist the foot when swinging, are neuroma-prone.

this is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.

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Thursday, May 26, 2016

This painkiller may slow the growth of cancer

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One of the most widely prescribed pain and anti-inflammation drug may also slow the growth rate of cancer, a new study has found. The study focused on the effects of celecoxib or Celebrex.
It targets an enzyme called "cyclooxygenase-2" (COX-2), which is linked to pain and inflammation, researchers said. This enzyme is also critical in the creation of prostaglandins, compounds that act like hormones and play a role in promoting tumour growth, they said. COX-2 expression is typically low in normal tissue, but high in multiple types of cancers, researchers said.

 "We were actually interested in determining what a particular signalling pathway does in cancer," said Joseph Kissil from The Scripps Research Institute (TSRI) in the US. "In the process, we found that it activates genes that promote survival of tumour cells and that they do so by turning on enzymes involved in inflammation, including COX2, which anti-inflammatory drugs like Celebrex inhibit," said Kissil.

Researchers conducted animal studies tracking the effects of celecoxib on the growth of cancer cells from a tumour type known as neurofibromatosis type II (NF2). In humans, NF2 is a relatively rare inherited form of cancer caused by mutations in the anti-tumour gene NF2, which leads to benign tumours of the auditory nerve, researchers said.

Animals received a daily dose of the drug, and tumour growth was followed by imaging. Analysis of the results showed a significantly slower tumour growth rate in celecoxib-treated models than in controls, they said. Using various approaches, the study also showed that a signalling cascade known as the Hippo-YAP pathway is involved in these results and that the protein YAP is required for the proliferation and survival of NF2 cells and tumour formation.

"Our study shows that COX2 inhibitors do have an effect on the tumour cells. They also have an impact on inflammatory responses that play a role in tumour growth," said William Guerrant from TSRI. "It is possible that in other cancers these effects might actually be stronger because of the drug's impact on inflammation," he said.

The findings were published in the journal Cancer Research.

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Tuesday, March 22, 2016

New Pill Lightens up Tumour Cells in Breast Cancer

 THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOUR PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.




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A new pill will lighten up tumourous cells in breast cancer cases to distinguish exactly between cancerous and benign growths, paving the way for a major shift from the current breast cancer screening methods which fail often to pinpoint lumps from benign to cancerous growth.

"Screening can potentially catch the disease early in some patients, but false positives can lead to unnecessary, aggressive treatments in patients who don’t need them," said Greg Thurber of the University of Michigan in the US.

Currently, mammograms screen breast tissue through X-rays and they give doctors information about a lump’s location and size, but they can not distinguish between cancerous and benign ones which requires further tests such as biopsies, involving surgery and still not 100 percent perfect.

Several patients and doctors begin treatment once suspicious lumps are found, and the painful period ranges from radiation or chemotherapy or surgery, which can take months and leave behind severe side effects. The new pill will help doctors to determine patients who really need treatment and those who do not.

The new pill containing an imaging agent that selectively binds to cancer cells or blood vessels that are unique to tumours will highlight the affected tissue giving clue to doctors about the dye fluoresces under near infrared light. Although at this wavelength, fluorescent tumours can only be detected 1 to 2 centimetres deep, pairing the technique with ultrasound in the same instrument should be able to detect most cancers, Greg Thurber said.

Tested in mice, the formulation’s 50 to 60% was absorbed into the bloodstream and it was able to bind specifically to cancer cells with little background noise in the image. The fluorescent signal from the tumour was far stronger than the signal from other issues.

If the team succeeds to develop the oral pill, the results will save several thousands of women who were found to be cancerous merely because of their dense breast tissues reflecting in mammograms.

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Friday, September 27, 2013

Girls who eat peanut butter 39pc less likelier to develop breast cancer later in life

Girls, who eat peanut butter or nuts two times a week, are 39 percent less likely to develop benign breast disease by the time they turned 30, compared to girls who never eat them a new study has revealed.

Research  analyzed the health histories of 9,039  girls from 1996 to 2001, when they were between the ages of 9 and 15, and later from 2005 to 2010, when they were 18 to 30 years old, it was  reported.
Senior author  said that the findings suggested that peanut butter could help reduce the risk of breast cancer in women. 

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Thursday, August 29, 2013

Young women who drink alcohol at greater risk of breast cancer

The more alcohol a young woman drinks before motherhood, the greater her risk of future breast cancer, a new study has warned.

If a female averages a drink per day between her first period and her first full-term pregnancy, she increases her risk of breast cancer by 13 per cent, according to a new study.

This is the first study to link increased breast cancer risk to drinking between early adolescence and first full-term pregnancy.

Previous studies have looked at breast cancer risk and alcohol consumption later in life or at the effect of adolescent drinking on non-cancerous breast disease.

"More and more heavy drinking is occurring on college campuses and during adolescence, and not enough people are considering future risk," said study co-author.

"But, according to our research, the lesson is clear: If a female averages a drink per day between her first period and her first full-term pregnancy, she increases her risk of breast cancer by 13 per cent," he said.

The researchers also found that for every bottle of beer, glass of wine or shot of liquor consumed daily, a young woman increases her risk of proliferative benign breast disease by 15 per cent.

Although such lesions are noncancerous, their presence increases breast cancer risk by as much as 500 per cent, said a researcher.

The findings are based on a review of the health histories of 91,005 mothers enrolled  from 1989 to 2009.

Researchers didn't consider the effects of adolescent and early adulthood drinking on women who didn't have a full-term pregnancy because not enough were represented among those studied.

Breast tissue cells are particularly susceptible to cancer-causing substances as they undergo rapid proliferation during adolescence and later.

Adding to the risk is the lengthening time frame between the average age of a girl's first menstrual cycle and the average age of a woman's first full-term pregnancy.

"Reducing drinking to less than one drink per day, especially during this time period, is a key strategy to reducing lifetime risk of breast cancer," he said.


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Wednesday, August 21, 2013

Cardiac Sarcoidosis:Causes, Types, Diagnosis, Treatment

Cardiac Sarcoidosis: Causes
The exact cause of sarcoidosis is unknown. Granulomas appear to be the result of an immune system response to an unidentified trigger. Infections agents as well as environmental exposures are thought to be possible precipitants for this immune response; however, no clear triggers or causes have been identified. Genetic mutations in white blood cell proteins (called human leukocyte antigens, or HLA) as well as chemicals that control inflammation (called cytokines) have also been linked to sarcoidosis.

Cardiac Sarcoidosis: Types
Cardiac sarcoidosis (CS) can take many forms, some benign and others serious.

Heart Rhythm Disorders: Interference of electrical movement through the heart is the one of the  complications of CS and can include complete heart block which can be life threatening. Alternatively, fast heart rhythms such as atrial flutter, atrial fibrillation, supraventricular tachycardia, and ventricular tachycardia can be present. Ventricular tachycardia occurs in almost 25 percent of CS patients and is of particular concern since it can lead to sudden cardiac death. These possible complications may occur suddenly without warning.
Heart Failure: Heart failure is another common complication of CS. Sarcoidosis can cause the heart muscle to weaken and/or stiffen, leading to fluid retention in the lungs, abdomen, and lower extremities. In extreme cases, an aneurysm can form due to weakening of the heart wall. Granulomas can also infiltrate the heart valves, causing leaky valves also resulting in heart failure.
Coronary Disease: Although rare, CS can cause inflammatory disorder of the heart arteries called vasculitis. In severe forms, vasculitis can lead to coronary artery blockages, chest pain and, ultimately, heart attacks.
Pericardial Disease: Inflammation of the sack around the heart, called pericarditis, is another rare but important form of CS.

Diagnosing cardiac sarcoidosis (CS) can be very challenging. There are no widely accepted guidelines for either screening or diagnosing CS. Moreover, the current available diagnostic tests are variable in their ability to detect CS. Because of its devastating nature, most patients with other forms sarcoidosis are screened for CS.

Initial cardiac evaluation may include an EKG, a signal averaged EKG, an echocardiogram and a Holter monitor (extended EKG). Additional imaging tests may include single positron emission computed tomography (SPECT), positron emission tomography (PET) and cardiac MRI. A positive heart biopsy confirms CS, but a heart biopsy may more often be negative or normal even when there is sarcoid in the heart, especially if heart function is normal.

Cardiac Sarcoidosis: Treatment
Controversy exists as to the best treatment for cardiac sarcoidosis (CS). However, treatment is generally directed at minimizing the inflammation associated with CS and protecting against the life-threatening complications.

Because of their anti-inflammatory properties, corticosteroids (cortisone, prednisone and methylprednisolone) are the first-line therapy. When patients cannot take steroids, or when combination therapy is necessary, medications such as methotrexate, azathioprine, mycophenolate and antimalarials are used.

Additional therapies for specific CS-related heart disorders may be necessary. For example, heart rhythm disorders such as complete heart block typically require placement of a permanent pacemaker, whereas ventricular tachycardia generally requires internal cardiac defibrillator (ICD) placement.


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