Do You Know Why Apples Are Good For You

Of course, you'll remember the good old saying " an apple a day, keeps the doctor and dentist away too". I'm sure not many know about apples keeping away the dentist. Eating apples can help cleanse and clean teeth, and fight bad breath. The fibrous content of apples cleans teeth by acting as a toothbrush and scrubbing away plaque from teeth, and removing other food debris. The acidity in an apple helps kill off bad bacteria that encourages bad breath. Be sure to leave the skin on the apple, since it is full of the mouth-healthy fiber that helps keep teeth and gums clean.
From strengthening the immune system, to preventing cancerous growths and losing weight, say hello to your apple a day!

 

How do apples help us?

Important research published in 2008 by the German cancer researchers showed that apples offer a significant health advantage. Those that ate one or more apples each day were shown to be healthier than those in the control group that ate no apples at all. They were found to have less risk of mouth cancer, larynx cancer, breast cancer, intestinal cancer, kidney cancer and ovarian cancer.
 
These findings corroborate new research, which showed that apple peel has strong antioxidant properties. These properties mean that apple peel is a powerful inhibitor of breast cancer cells. Researchers found that the higher the concentration of apples, the lower the concentration of cancerous cells.
 
Cancerous growths are uncontrollable cell growths that independently spread throughout the body. The growths are based on three principle levels. The first stage causes mutations in cell DNA. The second is when the growth becomes malignant and grows faster. And, in third, it metastasizes and spreads throughout the body.
 
In the event of a cancerous growth, apples aren't only used as antioxidants - they also improve immune system function, which helps clean out the growths in their early stages.
 
In addition to boosting the immune system and fighting cancerous growths, apples also help control the levels of cholesterol and sugar in the blood, prevent heart disease and improve mouth hygiene. The fact that they contain more than 80% water and a long line of essential vitamins, makes them one of the healthiest foods available.
Nutritional Fiber

Apples are considered a vital source of nutritional fiber. Eating one apple a day (with peel) can award us about 4.4 grams of nutritional fiber, which is a fifth of our recommended daily amount.
 
Nutritional fibers are nutrients found in foods that come from plants, and have a very important role in stimulating digestive system function. Since they are not digested and taken apart in the body, they sate our hunger for a longer period of time. Extensive research has shown that those that do not get their recommended daily amount (at least 25 grams a day), deny themselves a host of health benefits.

In addition, the researchers found that consuming these fibers is quite an effective method of losing weight.
 
The secret is in the chewing. Drinking apple juice will not give you the same health benefits as eating an apple will. A study conducted in China found that chewing can help the body regulate the amount of calories it absorbs from food.

What does this have to do with apples?

Everything. Apples are a terrific source of nutritional fiber, especially a group of fibers called Pectin. This is a group of complex carbohydrates that regulates our bowels, improves good cholesterol and has powerful antioxidant and antibacterial properties. 
 
Researchers have shown that consuming pectin instead of regular fiber doubles the time it takes the stomach to empty from one hour to two, meaning that we don't feel hungry for a longer time. In fact, a recent research paper titled: "Weight Loss Associated with a Daily Intake of Three Apples or Three Pears among Overweight Women", showed that women who were overweight and were instructed to eat an apple or pear before each meal lost significant weight just by doing so.

The women in the experiment were asked to eat regularly and just add the apple before the meal. What happened was that the apples and fibers crowded the stomach, increased the feeling of being full, and made the body absorb less calories.
 
Other sources of nutritional fiber are: pears, peaches, peas, carrots, seeds, nuts, peel of fruits and vegetables, legumes, whole grains, oats and whole wheat. But apples offer many more advantages.
 
So if you want to:
Lose weight, eat one apple a day.
Strengthen your immune system, eat one apple a day.
Control the level of cholesterol, eat one apple a day.
Prevent the spread of cancerous cells, eat one apple a day!
Good for teeth, prevents bad breath 

 

THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.                                    PS- THOSE INTERESTED IN RECIPES ARE FREE TO  VIEW MY BLOG-                                                                                           https://gseasyrecipes.blogspot.com/    

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High-cholesterol diet causes tumours to form 100 times faster

A news study now shows that high-cholesterol diets send cancer cells into overdrive and cause tumours to grow 100 times faster.

Scientists of the study have shown for the first time that the mechanism which means fatty cholesterol significantly increases the risk of colon cancers.

The research which was carried out by researchers, who made the discovery are other types of cancer too show similar frenzy under the influence of cholesterol.

Speaking about it, a Dr. said that they were excited to find that cholesterol affects growth of stem cells in intestines which in turn accelerates rate of tumour growth formation by more than 100 per cent.

He went on to add, “While the connection between dietary cholesterol and colon cancer is well established, no one has previously explained the mechanism behind it.”

The study,  investigated mice who were given a high cholesterol diet and others genetically modified to produce more cholesterol in their natural state.

Scientists observed that in both cases, extra cholesterol was a powerful trigger for the replication of intestinal stem cells which are responsible for the growth of the gut.

However, the rapid growth also meant that the growth of tumour cells accelerated rapidly as well.
Scientists are still debating whether cholesterol-busting drugs like statins, which are widely 
prescribed to people at risk of heart attacks or strokes, can lower risk of gut cancers.

According to the study, the report concludes: “We showed here that high cholesterol diet feeding increased cellular cholesterol levels in [gut] crypts and that cellular cholesterol content regulates the proliferation of ISCs.

Therefore, it says, it is logical that this previously unseen mechanism is what is driving up tumour growth in humans on a high cholesterol diet.

THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.    

PS- THOSE INTERESTED IN RECIPES ARE FREE TO VIEW MY BLOG-                      
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Certain probiotics could help women lose weight

According to a recent study certain probiotics could help women lose weight and keep it off.

Previous studies have suggested that the intestinal flora of obese individuals differs from that of thin people. This is most likely due to the fact that a diet high in fat and low in fiber promotes certain bacteria at the expense of others.

The researchers tried to determine if the consumption of probiotics could help reset the balance of the intestinal microbiota in favour of bacteria that promote a healthy weight.

They studied about 125 overweight men and women who underwent a 12-week weight-loss diet, followed by a 12-week period aimed at maintaining body weight.

Throughout the entire study, half the participants swallowed 2 pills daily containing probiotics from the Lactobacillus rhamnosus family, while the other half received a placebo.

After the 12-week diet period, researchers observed an average weight loss of 4.4 kg in women in the probiotic group and 2.6 kg in the placebo group.

However, no differences in weight loss were observed among males in the two groups.

"We don't know why the probiotics didn't have any effect on men. It may be a question of dosage, or the study period may have been too short," Professor Tremblay, who is also the Canada Research Chair in Environment and Energy Balance, said.

After the 12-week maintenance period, the weight of the women in the placebo group had remained stable but the probiotic group had continued to lose weight, for a total of 5.2 kg per person.

In short, women consuming probiotics lost twice as much weight over the 24-week period of the study.

Researchers also noted a drop in the appetite-regulating hormone leptin in this group, as well as a lower overall concentration of the intestinal bacteria related to obesity.

Probiotic is a compound of two Greek words: "pro," to signify promotion of and "biotic," which means life.

With the growing interest in probiotic interventions many studies are being carried out on the health benefits of consuming foods and supplements containing certain kinds of live bacteria. Many studies suggest that live-active cultures of probiotics can actually help prevent and treat a wide variety of ailments including irritable bowel syndrome, or IBS -- a hard-to-treat intestinal conditions, such as abdominal pain, cramps, bloating, diarrhea and constipation.

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Human stem cells converted to functional lung cells

Scientists have for the first time transformed human stem cells into functional lung and airway cells.

The advance, by Columbia University Medical Center (CUMC) researchers, has significant potential for modelling lung disease, screening drugs, studying human lung development, and, ultimately, generating lung tissue for transplantation.

“Researchers have had relative success in turning human stem cells into heart cells, pancreatic beta cells, intestinal cells, liver cells, and nerve cells, raising all sorts of possibilities for regenerative medicine,” said study leader Hans-Willem Snoeck.

“Now, we are finally able to make lung and airway cells. This is important because lung transplants have a particularly poor prognosis,” said Snoeck, professor of medicine (in microbiology & immunology) and affiliated with the Columbia Center for Translational Immunology and the Columbia Stem Cell Initiative.

“Although any clinical application is still many years away, we can begin thinking about making autologous lung transplants – that is, transplants that use a patient’s own skin cells to generate functional lung tissue,” Snoeck said.

The research builds on Snoeck’s 2011 discovery of a set of chemical factors that can turn human embryonic stem (ES) cells or human induced pluripotent stem (iPS) cells into anterior foregut endoderm – precursors of lung and airway cells.

In the current study, Snoeck and his colleagues found new factors that can complete the transformation of human ES or iPS cells into functional lung epithelial cells (cells that cover the lung surface).

The resultant cells were found to express markers of at least six types of lung and airway epithelial cells, particularly markers of type 2 alveolar epithelial cells.

Type 2 cells are important because they produce surfactant, a substance critical to maintain the lung alveoli, where gas exchange takes place; they also participate in repair of the lung after injury and damage.

The findings have implications for the study of a number of lung diseases, including idiopathic pulmonary fibrosis (IPF), in which type 2 alveolar epithelial cells are thought to play a central role.

“No one knows what causes the disease, and there’s no way to treat it,” said Snoeck.

“Using this technology, researchers will finally be able to create laboratory models of IPF, study the disease at the molecular level, and screen drugs for possible treatments or cures,” Snoeck said.

The study was published in the journal Nature Biotechnology. 

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How fibre-rich diet prevents diabetes and obesity

It has been known for year that a fibre-rich diet protects the organism against obesity and diabetes, and not a French-Swedish team of researchers has succeeded in elucidating this mechanism, which involves the intestinal flora and the ability of the intestine to produce glucose between meals.

The study also clarified the role of the intestine and its associated microorganisms in maintaining glycaemia. They will give rise to new dietary recommendations to prevent diabetes and obesity.

Most sweet fruit and many vegetables such as salsify, cabbage or beans are rich in so-called fermentable fibres. Such fibers cannot be digested directly by the intestine but are instead fermented by intestinal bacteria into short-chain fatty acids such as propionate and butyrate, which can in fact be assimilated by our bodies.

The protective effect of these fibers is well known to researchers: animals fed a fiber-rich diet become less fat and are less likely to develop diabetes than animals fed a fiber-free diet. Nevertheless, the mechanism behind this effect has until now remained a mystery.

The team headed by Gilles Mithieux, CNRS researcher in the “Nutrition et Cerveau” unit (Inserm / Universite Claude Bernard Lyon 1), wondered whether this mechanism could be linked to the capacity of the intestine to produce glucose.

The researchers subjected rats and mice to diets enriched with fermentable fibers, or with propionate or butyrate and observed a strong induction of the expression of genes and enzymes responsible for the synthesis of glucose in the intestine.

They showed that the intestine of these animals used propionate as precursor to increase the production of glucose. Mice fed a fat- and sugar-rich diet, but supplemented with fibers, became less fat than control mice and were also protected against the development of diabetes thanks to significantly increased sensitivity to insulin.

The work sheds light on the role of the intestinal flora which, by fermenting dietary fiber, provides the intestine with precursors to produce glucose and also demonstrates the importance of the intestine in the regulation of glucose in the body.

ps- this is only for information, always consult you physician before having any particular food/ medication/exercise/other remedies.

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Altering gut flora may increase lifespan

Having the right balance of gut bacteria may be key to enjoying a long healthy life, scientists say. 

Researchers at the Buck Institute for Research on Aging in US found that altering the symbiotic, or commensal, relationship between bacteria and the absorptive cells lining the intestine promoted health and increased lifespan in Drosophila (common fruit fly). 

The findings provide a model for studying many of the dysfunctions that are characteristic of the ageing gut and gives credence to the growing supposition that having the right balance of gut bacteria may be key to enjoying a long healthy life, researchers said. 

Lead author and Buck faculty Heinrich Jasper, said there is no systematic understanding of how we go from having a young, healthy gut to one that is old and decrepit. 

"Our study explores age-related changes in the gut that include increased oxidative stress, inflammation, impaired efficiency of the immune response, and the over-proliferation of stem cells," said Jasper. 

"It puts these changes into a hierarchical, causal relationship and highlights the points where we can intervene to rescue the negative results of microbial imbalance," Jasper said. 

He said the bacterial load in fly intestines increases dramatically with age, resulting in an inflammatory condition. 

The imbalance is driven by chronic activation of the stress response gene FOXO (something that happens with age), which suppresses the activity of a class of molecules (PGRP-SCs, homologues of PGLYRPs in humans) that regulate the immune response to bacteria. 

PGRP-SC suppression deregulates signalling molecules (Rel/NFkB) that are important to mount an effective immune response to gut bacteria. 

The resulting immune imbalance allows bacterial numbers to expand, triggering an inflammatory response that includes the production of free radicals. 

Free radicals, in turn, cause over-proliferation of stem cells in the gut, resulting in epithelial dysplasia, a pre-cancerous state. 

Jasper said the most exciting result of their study occurred when his group increased the expression of PGRP-SC in epithelial cells of the gut, which restored the microbial balance and limited stem cell proliferation. 

This enhancement of PGRP-SC function, which could be mimicked by drugs, was sufficient to increase lifespan of flies. 

"If we can understand how ageing affects our commensal population - first in the fly and then in humans - our data suggest that we should be able to impact health-span and lifespan quite strongly, because it is the management of the commensal population that is critical to the health of the organism," Jasper said. 

ps- this is only for information, always consult you physician before having any particular food/ medication/exercise/other remedies.

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