Monday, May 18, 2020

Do you really need to take a vitamin? 5 things to know before you buy

It seems like every corner of the internet is overstuffed with ads for vitamins, herbal remedies, fat-loss supplements, muscle-building shakes and sleeping pills.

As someone who's worked in the health fitness industry for years, I know that much, if not most, of it is just clutter. It's charlatans and hustlers trying to make a quick buck off of your pain points. It's great marketers who know that phrases like "lightning fast weight loss" and "banish cellulite forever" sell products that may or may not be straight-up flimflam.

In the largely unregulated supplement industry, many products are ineffective, full of fillers or undisclosed ingredients. Some are downright dangerous. Who can you trust? How do you know which supplements are best for you? What products are actually effective -- and safe to take?
I want to preface the rest of this article with two very important disclaimers:

First, it's impossible to cover everything you need to know about choosing safe and effective supplements in one article. If you want to learn more, you should read official information from the Food and Drug Administration (FDA), the Office of Dietary Supplements (ODS) and the US National Library of Medicine. While I cite many primary studies in this article, you can browse the PubMed database for more information on specific supplements., their uses, benefits and risks.

Second, although I have training in nutrition, anatomy and physiology, I am not a registered dietitian nor a doctor of any sort. If you are interested in taking supplements for a particular symptom or medical condition, please, please, please consult a registered dietitian or your doctor before doing so.

Now onto what you should know about supplements before you waste your money. 


1. Supplements aren't strictly regulated by the FDA or the USDA

Currently, the supplement industry is largely unregulated, especially compared to the food and drug industries. The FDA still uses an act passed nearly 20 years ago -- the Dietary Supplement Health and Education Act of 1994 (DSHEA) -- that only has one real stipulation: "Manufacturers and distributors of dietary supplements and dietary ingredients are prohibited from marketing products that are adulterated or misbranded."

This means the manufacturers themselves are responsible for testing the safety and efficacy of their products, as well as for labeling their own products. The FDA can crack down on a supplement after it hits the market if it's incorrectly labeled or unsafe, but by that time, damage may already be done.

You can learn more about what's required of supplement manufacturers by reading the FDA's FAQ on dietary supplements. However, FDA Commissioner Scott Gottlieb did announce in a February 2019 statement that he plans to implement stricter regulations, so things are definitely looking up for the supplement industry.

Nonetheless, here are a few examples of what has happened in the past because of the low-level regulation:

    Companies have sold highly concentrated caffeine powder and liquid in bulk to consumers. The FDA has ruled that an illegal and unsafe practice.
    A supplement brand sold products with dangerous hidden ingredients. The FDA has announced warnings to both consumers and the company.
    Supplement companies illegally claim to treat opioid use disorder. The FDA posted warning letters to the companies.
    Nearly 20 supplement brands sold products with unlawful claims about treating Alzheimer's disease. The FDA sent warning letters to all of the companies.

2. You shouldn't take the same supplements as everyone else
If your diet, lifestyle, fitness routine, sleep habits and health status aren't the same as anyone else's, why would it make sense to take the same supplements as everyone else?

For some supplements, this is obvious: You probably wouldn't feel inclined to take a calorie-dense, high-protein and high-carb post-workout shake if you weren't trying to build muscle. You also probably wouldn't reach for sleep aids if you don't have trouble sleeping at night.

For other supplements, the disconnect isn't so conspicuous. Everyone needs vitamins, right?

Yes, everyone does need vitamins and minerals and other certain nutrients (here's a very helpful PDF chart from the FDA on the main nutrients, their functions and RDAs), but not everyone needs the same amount of the same nutrient.

Take vitamin B12 as an example: People who eat a vegan or vegetarian diet may benefit from supplementing with B12 because this vitamin is found primarily in animal products or fortified products. If you eat eggs, dairy products, chicken, seafood or steak, you likely don't need additional vitamin B12.

If you're interested in learning more about which vitamins you actually need, I highly recommend reading The Vitamin Solution by Dr. Romy Block and Dr. Arielle Levitan, two doctors who founded Vous Vitamin, a personalized multivitamin company.

I found this book to  lay out all of the essential knowledge on vitamins, minerals and other supplements in a way that's easy to understand and can help you determine which supplements are best suited to you -- or at least open up a helpful discussion with your doctor.
 

3. Supplements don't replace whole foods
It's unfortunately a myth that taking vitamins and supplements can replicate a healthy diet. Just like you can't "out-exercise" a poor diet, you can't "out-supplement" one either. Vitamins can certainly help bridge the gap between what you get from your diet and what you don't, but using supplements as a way to "fix" your diet won't work.

There are so many nuances at play here. For example:

    Taking fat-soluble vitamins but failing to eat dietary fat may mean that your body doesn't adequately absorb the vitamins
    Taking a daily multivitamin but disregarding fruits and vegetables means you don't get the antioxidants or fiber found in plant foods
    Drinking protein shakes but not eating meat could present vitamin B12 deficiency over time (if you don't supplement B12 accordingly)
    Taking a vitamin D supplement without getting enough calcium might negate the supplement's beneficial effects on bone health

That list is far from comprehensive, but you can see that vitamins and supplements don't just magically undo poor eating habits. Scientific conclusions vary greatly -- from "we don't need vitamins at all" to "the benefits outweigh the risks" -- but the general consensus seems to be that vitamins and supplements can help prevent nutrient deficiencies in certain populations and when taken correctly and support health in conjunction with a nutritious diet.


4. Yes, you can overdose vitamins and supplements
One common vitamin myth is this: "If I take too many vitamins, it's fine, because my body will only keep what it needs and get rid of the rest as waste."

This is a pervasive mindset but a dangerous one. You can, in fact, overdose on vitamins. The term is "vitamin toxicity" and it can happen with any vitamin. For almost every vitamin, there is an established Recommended Daily Allowance (RDA) or Adequate Intake (AI), as well as a Tolerable Upper Intake Level (UL).

The RDA or AI signifies an ideal daily intake while the UL indicates the high end of what's safe to consume. RDAs, AIs and ULs are all values under Dietary Reference Intakes (DRIs), the set of reference values assigned to foods and supplements for consumption.

Recently, experts have seen an increase in vitamin D toxicity, likely related to the touting of vitamin D's benefits on immune function, bone health and mood.

It's not just vitamins that can be toxic either: Minerals taken in high doses can be toxic, as can electrolytes, herbs and sports supplements. Zinc, for example, a mineral known and loved for its immune-boosting properties, can actually cause immunosuppression in extremely high doses.

Pre-workout supplements high in caffeine can cause abnormal heart rhythms and severe overdoses can be fatal. Potassium, a well-known electrolyte found in foods such as bananas and spinach and in sports drinks, can also cause toxicity. Called hyperkalemia, this condition can lead to muscle weakness, fatigue, nausea and, in severe cases, life-threatening heart arrhythmias.

Surpassing the UL of any vitamin, mineral, electrolyte or other supplement can cause harm, so be careful to do your research on any supplements you intend to take.
 

5. Supplements may dangerously interact with medications you take
If you currently take prescription or over-the-counter medications regularly, you should talk with your doctor about drug-nutrient interactions.

A drug-nutrient interaction is any reaction that occurs between a vitamin, mineral, antioxidant, electrolyte or other nutrient and a medication. A drug-supplement interaction is any reaction that occurs between a supplement and a medication.

Good intentions to supplement your diet with vitamins, minerals and herbs can backfire and cause complications. Take these examples:

    Consuming too much vitamin K, a fat-soluble vitamin that acts as a coagulant, can interfere with warfarin, a blood thinner.
    St. John's Wort, a popular supplement used to treat depression, can lead to serotonin syndrome (dangerously high levels of serotonin in the blood) if taken in conjunction with selective serotonin reuptake inhibitors (SSRIs).
    Kava, an herbal supplement used to treat anxiety, has several potential drug interactions, including antipsychotics, benzodiazepines (anxiety medications) and diuretics. 

How to choose the right supplements for you
If you're generally healthy and want to take supplements for overall health, I think the best bet is to use a personalized multivitamin service, such as Vous Vitamin, Baze or Persona Nutrition. This isn't as good as going to a doctor or dietitian, but it's far better than just swiping the first multivitamin bottle you see into your cart at the grocery store.

Some of these companies have more thorough personalization processes than others, but in general, with a personalized multivitamin, you can feel confident that you're not getting too much of a specific vitamin or consuming a vitamin that may be necessary or actually harmful to you.

If you don't go that route (and even if you do), you should always (always!) look for signs that a supplement is legitimate. By legitimate, I mean it's undergone third-party testing and/or evaluation, and it is certified not to include any ingredients other than what's on the label (aka it doesn't have any shady fillers). Those signs are:

    National Sanitation Foundation (NSF) certification. The NSF is a third-party evaluation agency for food and dietary supplements. When a supplement sports the NSF-certified label, it means it has undergone a scrutinous safety and risk assessment, and continuously undergoes "regular on-site inspections of manufacturing facilities and regular re-testing of products to ensure that they continue to meet the same high standards required to maintain certification over time." 


    US Pharmacopeia (USP) Verified Mark. The USP is a nonprofit, independent organization that vets medications, foods and dietary supplements to determine their safety and efficacy. The USP Verified Mark on a supplement means that supplement meets four critical components, which you can read about on the USP standards for supplements page.


    Good Manufacturing Practices (GMP) certification. This is the one FDA-related certification for supplements. The FDA has established Good Manufacturing Practices for supplement production, and dietary supplements that have this certification meet the FDA's guidelines for production.

Even better yet, look for a nutrition facts label versus a supplement facts label. A nutrition facts label means the product is sold as a food product, not a supplement, which means it has been evaluated and approved by the FDA for human consumption. A whole-food supplement with a nutrition facts label, an NSF certification, a USP Verified Mark and GMP certification is the best of the best.
27 tips to help you sleep better, starting tonight.


To avoid vitamin toxicity, check the labels of every supplement you take. If you take multiple supplements every day and also get vitamins from food, you can put yourself at risk for vitamin toxicity -- for instance, if your protein shake is fortified with vitamin B12 and your multivitamin contains 250% of the DRI for vitamin B12, you may want to alternate them or choose a different protein shake that isn't fortified.

Finally, I'll end with the same sentiments I opened with: Please consult your doctor or a registered dietitian if you're interested in taking vitamins or supplements for a specific symptom or medical condition.

Not only can supplements dangerously interact with medications you may be taking already, it's important to rule out any medical conditions that may need to be treated with prescription medication. 


This is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.     

https://gscrochetdesigns.blogspot.com. one can see my crochet creations  
https://gseasyrecipes.blogspot.com. feel free to view for easy, simple and healthy recipes    
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Tuesday, December 03, 2019

Why people with Type 1 diabetes have a greater risk for heart diseases; preventive measures

Cardiovascular events are becoming more common, occuring at a younger age than usual - equally both in males and females. But people with Type 1 diabetes mellitus (T1DM) have a higher risk of developing heart disease than the general population, although the reason behind this hasn’t been clearly understood. In fact, people with both types of diabetes - Type 1 and Type 2 - have a higher risk for heart disease, perhaps, just for different reasons.

The Pittsburgh Epidemiology of Diabetes Complications (EDC) study showed that the incidence of major coronary artery disease (CAD) events in young adults (aged 28-38 years) with Type 1 diabetes mellitus was 0.98 per cent per and surpassed 3 per cent per year after age 55 years, making it the leading cause of death in that population. Patients with Type 1 diabetes can prevent or reduce their risk of developing an immune reaction to their own body, one that specifically attacks the heart, by keeping their condition under control through a combination of medication and lifestyle changes.
The link between CVD and Type 1 diabetes

The main risk factors responsible for cardiovascular disease in Type 1 diabetes are hypertension, cigarette smoking, obesity, lipid levels, inflammation, microalbuminuria, and poor glycemic control. According to Dr M Sai Sudhakar, Director - Cath lab, Chief Interventional Cardiologist and Chief Cardiac Transplant Physician at Gleneagles Global Hospitals, Lakdi ka Pul, Hyderabad, there are several potential explanations why patients with Type 1 diabetes have a greater risk for CVD. A scientific statement from the American Heart Association and American Diabetes Association explained how type 1 diabetes mellitus increases your risk for CVD. Here's how:
 

Genetic polymorphisms appear to influence the progression and prognosis of CVD in Type 1 diabetes mellitus.
 

People exposed to higher blood sugar levels were more likely to develop an autoimmune response to the heart proteins linked to later development of heart disease, including heart attack and death.
 

Abnormal vascular findings associated with atherosclerosis are seen in patients with T1DM. 

Endothelial function alters even at a very early stage of type 1 diabetes mellitus. Atherosclerosis - When plaque clogs your arteries - in the setting of Type 1 diabetes mellitus is characterised by more severe stenoses, more extensive multiple vessels and more distal coronary findings than in patients without the disease.
 

Neuropathy in Type 1 diabetes mellitus can cause abnormalities in the response of coronary vasculature to sympathetic stimulation, which may manifest as resting tachycardia or bradycardia, exercise intolerance, orthostatic hypotension, loss of the nocturnal decline in BP, or silent myocardial ischemia on cardiac testing. These abnormalities can result in delayed presentation of CVD.
 

Inflammation operates in T1DM via multiple mechanisms, which may include hyperglycemia and hypoglycemia, excess adiposity or altered body fat distribution, thrombosis, and adipokines.

Prevention

The good news is, there are many things you can do to reduce your risk of developing heart disease or having a heart attack. These include:

Risk modifications such as avoidance of smoking, maintenance of a normal weight, and consumption of a balanced diet replete in fruits and vegetables and enriched in whole grains, but low in saturated fat and sodium are generally recommended.
 

Aggressive diabetes and lipid management is of utmost importance. A lower BP goal of <130 appropriate="" be="" br="" in="" individuals.="" may="" mmhg="" younger=""> 
All patients with Type 1 diabetes mellitus and hypertension or albuminuria are usually advised to take an angiotensin-converting enzyme (ACE) inhibitor -- a class of medication used to treat certain heart and kidney conditions. If an ACE inhibitor is not tolerated, an angiotensin II receptor blocker (ARB) may have similar efficacy.
 

People suffering from diabetes are vulnerable to heart ailments, which may trigger a stroke unless the patient adopts a healthy lifestyle. It is essential for diabetic patients to maintain their cholesterol level at the prescribed limit, regular physical activity, and reduce their body weight in addition to taking the right medication.

Following the right preventive methods and appropriate treatment may help reduce the risk of heart complications and improve the life expectancy in patients with diabetes.

this is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.     
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Wednesday, November 20, 2019

Yoga improves sleep, curbs pain

Yoga is not only a healthy way of meditating and maintaining overall wellness, but can also better an individual’s sleep along with limiting their dependence on medicines for back pain and sleep disturbance. A new study has highlighted that Yoga and physical therapy (PT) are effective approaches to treating the aforementioned conditions while reducing the need for medication.

The research showed significant improvements in sleep quality lasting 52 weeks after 12 weeks of yoga classes or one-on-one PT, which suggests a long-term benefit of these non-pharmacologic approaches. In addition, participants with early improvements in pain after 6 weeks of treatment were three and a half times more likely to have improvements in sleep after the full, 12-week treatment, highlighting that pain and sleep are closely related.

Sleep disturbance and insomnia are common among people with chronic low back pain (cLBP). Previous research showed that 59 per cent of people with cLBP experience poor sleep quality and 53 per cent are diagnosed with insomnia disorder. Why medicines aren’t a good option is because it can have serious side effects, and risk of opioid-related overdose and death increases with use of sleep medications.

“Identifying holistic ways to treat these conditions could help decrease the reliance on these medications as well as keep patients safer and more comfortable,” said study lead, Eric Roseen, DC, MSc, a researcher in the department of family medicine at BMC. 

this is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.     
https://gscrochetdesigns.blogspot.com. one can see my crochet creations  
https://gseasyrecipes.blogspot.com. feel free to view for easy, simple and healthy recipes    
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Tuesday, November 19, 2019

7 everyday medication mistakes that can make you sick

Avoid making these mistakes!
We all know that the right combination of medicines can cure any disease, but a slight mistake can put us at risk of serious illnesses or can even turn fatal. But still, a lot of people make dangerous drug mistakes every year, which lands them in the emergency room of a hospital. As per data, more than 1.5 million make dangerous drug mistakes every year and a majority of them are made by senior citizens. One of the best ways to reduce the risk of a medication error is to be well aware of the drugs you are taking and its potential side effects. Here is a list of 7 common medical mistakes that you should avoid to stay healthy and safe:


Mixing drugs incorrectly
Taking two counteracting drugs together can actually make you sick. The interaction of the two drugs in the body can reduce the effectiveness of both the medicines and can even lead to unpleasant side-effects. Like taking antidepressants and methadone together can be an issue. Even over-the-counter drugs should be avoided. 


Taking medication without complete knowledge
Whenever your doctor prescribes you new medicines or you are taking over-the counter-drugs, it is better to gain complete knowledge about it. You should know how to take the drugs, when to take it and its side-effects. Gaining complete knowledge about the medicines you are going to take will prevent you from making a medication error.

Taking high dose of drugs
You should always take medicines as prescribed by your doctor. Taking a high dose of medicines can cause serious liver damage and it can also cause side-effects. Apart from this, it may also lead to drowsiness, confusion, chest pain, vomiting, and diarrhea. Even taking medicines too often should be avoided.


Taking medicines infrequently
If you are not taking your medicines regularly then you are putting your health at risk. Antidepressants, steroids, and blood-thinning medicines should not be skipped. Doing so can cause grave danger to your health. 


Taking drugs on an empty stomach
The wrong combination of food also causes hindrance in the absorption of the drug from the stomach into the body. There are some medicines which need to be taken on an empty stomach and some after the meal. Ignoring these small details will reduce the effectiveness of the drugs. 


Taking medicines on your own
This is a common mistake most people make. They self-diagnose the symptoms and take medicines accordingly, which at times goes wrong. It is best to consult your doctor before having any kind of drugs as it is a matter of your health.


Taking other people's medicines
Just because you and your partner are suffering from high blood pressure, doesn't mean you both need the same medication. Doctors prescribe medicines based on your fitness level, age, and other medical complications. Taking other people's tablets can make your health condition even worse.


this is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.     
https://gscrochetdesigns.blogspot.com. one can see my crochet creations  
https://gseasyrecipes.blogspot.com. feel free to view for easy, simple and healthy recipes    
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Sunday, August 25, 2019

New skin patch could deliver cancer medication without pain in one minute

Researchers have developed a new skin patch that could efficiently deliver medication to attack melanoma cancer cells.

The study is an advance toward developing a vaccine to treat melanoma.


Our patch has a unique chemical coating and mode of action that allows it to be aplied and removed from the skin in just a minute while still delivering a therapeutic dose of durgs, said one of the researcher.


Researchers have designed a new pH-responsive polymer with 2 parts.


The first part containes amine groups that are positively charged at the pH at which they make the microneedles, but that becomes neutral at the pH of the skin, the researcher explained.


The second part contains carboxylic acid groups with no charge when the microneedles are made, but which become negatively charged when the patch is applied to the skin. 


So, there is an overall change in charge from positive to negative, he said.


While sticky negative-positive -negative layers are still required for layer-by-layer (LbL) film construction, the team's patch quickly switches to repelling negative-negative-negative layers when placed on the skin. After the microneedles pierce the skin and implant the LBL drug film beneath the skin, the drug leaves the patch quickly.


Using chicken ovalbumin as a model antigen, the team vaccinated mice with their patches and compared the results with intramuscular and subcutaneous injections.


The microneedle treatment produced nine times the antibody level as compared to intramuscular injections ( e.g. used for flu shots) and 160 times the antibody level compared to subcutaneous injections ( e.g., used for measles vaccines). They also saw efficient immune activation in surgical samples of human skin.


Our patch technology could be used to deliver vaccines to combat different infectious diseases, he said. But, we're excited by the possibility that the patch is another tool in the oncologists' arsenal against cancer, specifically melanoma, he continued.


To make melanoma vaccine, the researchers developed an antigen that includes a marker frequently over-expressed by melanoma cells, as well as an adjuvant, which creates ageneralised danger signal for the immune system and boosts its response. Then, they tested different LbL microneedle film arrangements of antigen and adjuvant in immune cells derived from mice.


From these experiments, the researchers identified the optimal LbL microneedle structure that appears to activate immune cells directly accessible in the skin. In living mice, these cells could, in turn, migrate to the lymphatic system and recruit other immune cells to attack the melanoma tumour. The researchers now plan to test patches on melanoma tumours in mice.


We're using low-cost chemistry and a simple fabrication scheme to transform vaccination, he said. Ultimately, we want to get a device approved and on the market, he added.




THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.                                    PS- THOSE INTERESTED IN RECIPES ARE FREE TO  VIEW MY BLOG-                                                                                           https://gseasyrecipes.blogspot.com/                                                                                                                                                FOR INFO ABOUT KNEE REPLACEMENT, YOU CAN VIEW MY BLOG-                                                                       https:// kneereplacement-stickclub.blogspot.com/                                                                                                                     FOR CROCHET DESIGNS                                                                                                   
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Friday, June 14, 2019

Lifestyle Diseases - Can Lifestyle Medicine Cure Them?

Most of the illnesses that are the bane of our existence are the outcome of poor lifestyle choices and environmental factors. Majority of the Indian population, especially young adults are suffering from poor health conditions due to an unhealthy lifestyle.

What triggers poor lifestyle choices?
• People like eating lip-smacking fast food, which really does no favour to their bodies.
• Stress and anxiety accompany us every day of our lives. Deadlines at the workplace, peer pressure, the imperative to adhere to societal norms can damage anyone’s physical and psychological health. The need to keep out and the fear of missing out makes us lead a fast life that does not contribute to our health.
• These self-destructive activities are manifesting themselves all around us in the form of a host of physical ailments triggered by unhealthy lifestyles and reaction to a compromised environment. 

These are called chronic diseases and are a primary cause of mortality today.

The distressing rise in chronic ailments like diabetes, asthma, obesity, sleep apnea, osteoarthritis has worried people in the medical and pharmaceutical industry.

What is Lifestyle Medicine?
The medicines that were prepared in the wake of the research are called lifestyle medicine. Their goal is two-fold, i.e., to heal the diseases by understanding the causes and to prevent recurrence of the illness. To sum it up, lifestyle medicines are responsible for the diagnosis, treatment and prevention of chronic illnesses.

Is there more to Lifestyle Medicines than just pills?
Lifestyle medicines are not just tablets you swallow. If you opt for lifestyle medicine, you have to commit to a rigorous and healthy lifestyle. Doctors prescribing this kind of medication ask you to consult a nutritionist who prepares a diet chart for you that will help allay your ailments as well as provide the right proportion of nutrition based on your age, sex and weight.

Similarly, your doctor will advise you to take up new physical activities like joining the gym, jogging, walking, swimming, etc. A healthy diet and regular exercise can offset many lifestyle diseases like obesity, cardiac problems, and can bring Type 2 diabetes and asthma under control.
If you live in a metropolitan city, you are prone to breathing in toxic fumes and ingesting polluted food and water. For lifestyle medicines to work, you should take time to retire to the seaside or the mountains where the air is conducive to recuperation.

Lifestyle medicine is modern technology. People are making themselves sick because of their lack of foresight. This technology encompasses the treatment of chronic diseases, promoting stress management, a better understanding of environmental factors that are ruining our health and sensitizing the society to come to the aid of the ailing people.

THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.                                    PS- THOSE INTERESTED IN RECIPES ARE FREE TO  VIEW MY BLOG-                                                                                           https://gseasyrecipes.blogspot.com/                                                                                                                                                FOR INFO ABOUT KNEE REPLACEMENT, YOU CAN VIEW MY BLOG-                                                  https:// kneereplacement-stickclub.blogspot.com/                                                                      FOR CROCHET DESIGNS                                                                                                                                                                                          https://gscrochetdesigns.blogspot.com



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