Obesity May Up Risk Of Cancer In Teens

Does your 13 year old weigh much more than his BMI? Is he/she always surrounded by fattening and sugary foods? It is time you do something about the condition, or he/she might be at a risk of  developing cancer. According to a latest study, obesity increases risk of 13 different cancers in young adults.The study published recently, demonstrated how obesity may shift certain cancers to younger age groups, and intensify cellular mechanisms promoting the disease.

Cancer's increasing frequency in young adults has taken the entire medical circuit by storm. Earlier the disease was associated with people in their 50's.

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The new meta-analyses integrates animal studies, clinical trials, and public health data to help explain rising cancer rates among young adults.

Explaining how the childhood obesity "pandemic" promotes cancer, the study also offered approaches to better track the health crisis, and hopefully avert the risk.

Obesity is a disorder characterized by excessive body fat that increases the risk of health problems. Young people with body mass indexes (BMIs) over 30 are more likely to experience aggressive malignancies, noted the authors of the study.

The risk of cancer may remain even after the weight loss. The greater the body weight, the greater is the risk of cancer. It may alter a person's DNA, that may add up with time, which may even stay long after weight loss. If you lose weight, it improves the prognosis and may lower your risk, but it never goes away completely, noted the researchers.

The state of obesity is closely linked to stages of cancer progression. According to the researchers, obesity triggers the immune system in such a way, that they produce harmful byproducts like peroxide and oxygen radicals that mutate DNA.

Obesity can also take a direct toll on your metabolism. It can alter it in a way, causing growth factor and hormone imbalances that help cancer cells to grow and multiply.

The changes in the gut flora, could be severely affected by obesity too. These changes may facilitate tumor-promoting species to thrive.

The scientists also explained how acid reflux in obese individuals may damage swallowing tubes and elevate the risk of esophageal cancer.

The researchers said, even if one is successful in blocking one pathway, the obesity- induced cancer takes another path, and the trigger multiple other risks.

One of the studies that were part of the meta-analysis was conducted on 1.1 million Israeli men who were tracked over time. Those who were overweight in adolescence (age 16-19) had a 1.5-fold increased risk of developing colon cancer by age 48.

The researchers reinforced the idea of documenting health data, including BMI, throughout a patient's life. Doctors are advised to always scan for the history of obesity. Many cancer patients present after significant weight loss, which could cause doctors to overlook obesity-related factors.

Electronic medical records may help build databases that can detect weight loss patterns, the researcher suggested. About, 110 million children and adolescents with obesity worldwide remain at risk of developing obesity-associated cancers. A comprehensive data tracking the weight gain and weight of these children are a need of the hour.

From children to adults, obesity sees no age and can affect anybody. Re-organising your kitchen, swapping the fat-laden unhealthy junk with nutrient-dense food is the best gift you can give to yourself. Swap refined carb sources for whole grains. Whole grain manages to retain all the nutrients that are processed in the refining. Stock up on whole grains like bajra, ragi, maize and jowar and use them often. Try red, black and brown rice instead of white rice .You can use these whole grains for breakfast porridge. Just like grains, whole dals are also a better bet than the washed dals. Rajma, and chana dals are some of the healthiest dals you can fill up your shelves with. You can cook them, have them in sprouts or in soups. Avoid red meat and opt for lean meat like chicken and salmon. Adding protein with every meal could prove to be a game changer for anyone trying to lose weight. Load up on seasonal vegetables. They provide both soluble and insoluble fibres in addition to vitamins, minerals and antioxidants.

Starving is not a sustainable way to lose weight. A balanced and healthy diet can help one manage obesity better.

Why smoking is so terribly addictive

Researchers have tried to explain how nicotine exploits the body’s cellular machinery to promote addiction.

According to the Center for Disease Control and Prevention, nicotine activates receptors known as nAChRs and, remarkably, unlike most other drugs of abuse, it acts as a “pharmacological chaperone” to stabilize assembly of its receptors within the Endoplasmic Reticulum (ER) and increase their abundance at the cell surface (up-regulation).

Up-regulation of nAChRs plays a major role in nicotine addiction and, possibly, in the decreased susceptibility of smokers to Parkinson’s disease.

Receptors containing an alpha6 subunit (alpha6* nAChRs) are abundant in several specific brain regions.

Researchers from the California Institute of Technology in Pasadena used mice expressing alpha6 labeled with a fluorescent protein to show that exposure to nicotine—at a level comparable to that in human smokers—up-regulated alpha6* nAChRs in these areas of the brain.

ps- this is only for information, always consult you physician before having any particular food/ medication/exercise/other remedies.

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Green tea can improve your memory

Chemicals found in green tea can boost your memory and learning skills, a new study has found.

Researchers  found that chemical properties of green tea affect the generation of brain cells, providing benefits for memory and spatial learning.

Scientists said it has long been believed that drinking green tea is good for the memory.

Spatial memory is the part of memory responsible for recording information about one’s environment and its spatial orientation.

There has been plenty of scientific attention on its use in helping prevent cardiovascular diseases, but now there is emerging evidence that its chemical properties may impact cellular mechanisms in the brain.

The study focussed on the organic chemical EGCG, (epigallocatechin—3 gallate) a key property of green tea.

While EGCG is a known anti—oxidant, the team believed it can also have a beneficial effect against age—related degenerative diseases.

We proposed that EGCG can improve cognitive function by impacting the generation of neuron cells, a process known as neurogenesis.

The research was focussed on the hippocampus, the part of the brain which processes information from short—term to long—term memory.

The researchers found that ECGC boosts the production of neural progenitor cells, which like stem cells can adapt, or differentiate, into various types of cells.

The team then used laboratory mice to discover if this increased cell production gave an advantage to memory or spatial learning.

The researchers ran tests on two groups of mice, one which had imbibed ECGC and a control group.

The mice were trained for three days to find a visible platform in their maze. Then they were trained for seven days to find a hidden platform.

Researchers found that the ECGC treated mice required less time to find the hidden platform. Overall the results revealed that EGCG enhances learning and memory by improving object recognition and spatial memory.

We have shown that the organic chemical EGCG acts directly to increase the production of neural progenitor cells, both in glass tests and in mice.