Tobacco plant may aid in treating diabetes, arthritis
Tobacco plants can be used to produce an
anti-inflammatory protein that can have powerful therapeutic potential
for treating conditions like Type-2 diabetes, stroke, dementia and
arthritis, more effectively and at an affordable price, researchers say.
A team of researchers used tobacco plants to produce large quantities of a human protein called Interleukin 37, or IL-37 — naturally produced in the human kidney in very small quantities.
“This protein is a master regulator of inflammation in the body, and has been shown in pre-clinical models to be effective in treating a whole host of inflammatory and autoimmune diseases,” said a Professor.
“The human kidney produces IL-37, but not nearly enough to get us out of an inflammation injury.”
While IL-37 has shown promise in animal models, it’s use clinically has been limited because of the inability to produce it in large quantities at a price that is feasible clinically. Currently, it can be made in very small amounts using the bacteria E. coli, but at a very high cost.
That’s where the tobacco plants come in and pave the way to provide treatments that are effective and affordable, according to the study published recently.
“The plants offer the potential to produce pharmaceuticals in a way that is much more affordable than current methods,” said a scientist.
“Tobacco is high-yield, and we can temporarily transform the plant so that we can begin making the protein of interest within two weeks.”
The team is now investigating the effect that IL-37 has for preventing organ injury during transplantation. When an organ is removed for transplantation and then transferred to a recipient, inflammation occurs when the blood flow is restored to the organ.
A team of researchers used tobacco plants to produce large quantities of a human protein called Interleukin 37, or IL-37 — naturally produced in the human kidney in very small quantities.
“This protein is a master regulator of inflammation in the body, and has been shown in pre-clinical models to be effective in treating a whole host of inflammatory and autoimmune diseases,” said a Professor.
“The human kidney produces IL-37, but not nearly enough to get us out of an inflammation injury.”
While IL-37 has shown promise in animal models, it’s use clinically has been limited because of the inability to produce it in large quantities at a price that is feasible clinically. Currently, it can be made in very small amounts using the bacteria E. coli, but at a very high cost.
That’s where the tobacco plants come in and pave the way to provide treatments that are effective and affordable, according to the study published recently.
“The plants offer the potential to produce pharmaceuticals in a way that is much more affordable than current methods,” said a scientist.
“Tobacco is high-yield, and we can temporarily transform the plant so that we can begin making the protein of interest within two weeks.”
The team is now investigating the effect that IL-37 has for preventing organ injury during transplantation. When an organ is removed for transplantation and then transferred to a recipient, inflammation occurs when the blood flow is restored to the organ.
THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE
HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.
PS-
THOSE INTERESTED IN
RECIPES ARE FREE TO VIEW MY BLOG-
https://gseasyrecipes.blogspot.com/
FOR INFO ABOUT KNEE
REPLACEMENT, YOU CAN VIEW MY BLOG-
https:// kneereplacement-stickclub.blogspot.com/
FOR CROCHET DESIGNS https://gscrochetdesigns.blogspot.com
Labels: affordable, aid, anti-inflammatory, Arthritis, auto-immune disorders, dementia, diabetes, protein- IL-37, stroke, therapeutic properties, tobacco plant, treating, type 2 diabetes
posted by G S Iyer at 10:05 PM
0 comments
