Blood vessels may turn into bone-like particles with age

Researchers have discovered that blood vessels within bone marrow may progressively turn into bones with advancing age.

The study suggested that ossified particles may contribute to  diseases such as vascular calcification, heart attack, stroke and inadequate blood supply to the limbs.

By examining seemingly unrelated images and linking the details of them together, the author was able to posit the presence of bone-like particles in the blood, she said.

In fact, some of the ossified particles are large enough to clog the smallest blood vessels in the vascular tree, she added.

Approximately 610,000 people die each year from a heart disease-related event, making it the leading cause of death for both men n women in the U.S.

Vascular calcification is a common characteristic and risk factor for morbidity and mortality, she said. These bone-like particles are potentially more dangerous because of their sharp edges.

Some of the ossified particles have sharp tips and edges that could damage the lining of blood vessels, she said. This damage could initiate events leading to atherosclerosis ( build-up of plaque), which can restrict blood flow over time.

The discovery of these bone-like particles could help physicians detect and treat potentially life-threatening conditions.

THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.                                    PS- THOSE INTERESTED IN RECIPES ARE FREE TO  VIEW MY BLOG-                                                                                           https://gseasyrecipes.blogspot.com/                                                                                                                                                FOR INFO ABOUT KNEE REPLACEMENT, YOU CAN VIEW MY BLOG-                                                                       https:// kneereplacement-stickclub.blogspot.com/                                                                                                                     FOR CROCHET DESIGNS                                                                                                   

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When looking for etiologies related to vascular calcification, heart attack and or stroke, perhaps we should consider if and how ossified particles contribute to these diseases, she said.

Magnesium levels have effect on Vitamin D

Magnesium levels may have an effect in metabolising Vitamin D, says a recent study.

Researchers found that Vitamin D can’t be metabolised without sufficient magnesium levels.

“People are taking Vitamin D supplements but don’t realise how it gets metabolised. Without magnesium, Vitamin D is not really useful or safe,” said a researcher.

Researchers have explained that the consumption of Vitamin D supplements can increase a person’s calcium and phosphate levels even if they remain Vitamin D deficient. People may suffer from vascular calcification if their magnesium levels aren’t high enough to prevent the complication.

Patients with the right amount of magnesium levels require less Vitamin D supplementation to achieve sufficient Vitamin D levels. Magnesium also reduces osteoporosis, which helps to mitigate the risk of bone fracture that can be attributed to low levels of Vitamin D.

Deficiency in either of these nutrients is reported to be associated with various disorders, including skeletal deformities, cardiovascular diseases, and metabolic syndrome.

While the recommended daily allowance for magnesium is 420 mg for males and 320 mg for females, the standard diet in the United States contains only about 50 per cent of that amount. Almost half of the total population is estimated to be consuming a magnesium-deficient diet.

Researchers have stated that the magnesium consumption from natural foods has decreased in the past few decades, owing to industrialised agriculture and changes in dietary habits. Magnesium status is low in populations who consume processed foods that are high in refined grains, fat, phosphate, and sugar.

“By consuming an optimal amount of magnesium, one may be able to lower the risks of Vitamin D deficiency, and reduce the dependency on Vitamin D supplements,” he noted. Magnesium is the fourth most abundant mineral in the human body after calcium, potassium, and sodium.

THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.                                                                                                                                                                                                                                                                                        PS- THOSE INTERESTED IN RECIPES ARE FREE TO  VIEW MY BLOG-                                                                                           https://gseasyrecipes.blogspot.com/                                                                                                                                                                             FOR INFO ABOUT KNEE REPLACEMENT, YOU CAN VIEW MY BLOG-                                                                                                                             https:// kneereplacement-stickclub.blogspot.com/                                                                                       FOR CROCHET DESIGNS                                                                                                                                                                                                                                 https://gscrochetdesigns.blogspot.com   

Major Signs You Are Magnesium Deficient

Sometimes, you might not be aware of the fact that the eye twitches, muscle spasms, unexplained fatigue or weakness, or abnormal heart rhythms you experience are only symptoms of its deficiency in the body.

Apparently, only 1 percent of magnesium in the body is distributed in the blood, and most of it is stored in the bones and organs. Magnesium deficiency is also known as “invisible deficiency”, as numerous people are not even aware they are suffering from it.


It has been estimated that over 80 percent of Americans lack this mineral in their body. Another study found that only 25 percent of the population in the U.S. gets the recommended daily amount of 310 to 320 milligrams (mg) for women and 400 to 420 for men.

Moreover, a medical and naturopathic doctor, claims that even if you get this amount, it is “just enough to ward off outright deficiency”.

Despite its role in the health of your bones and heart, magnesium can do a lot more! Apparently, research has found 3,751 magnesium-binding sites on human proteins, showing its vital role in overall health and diseases.

It is included in over 300 different enzymes in the body and is helps the detoxification of the body, which prevents damage due to heavy metals, environmental chemicals, and other toxins. Plus, it also plays a role in:

• Acting as a precursor to neurotransmitters such as serotonin
• Activating adenosine triphosphate (ATP) and thus creating energy
• Activating muscles and nerves
• Helping the digestion of fats, proteins, carbohydrates
• Serving as a building block for RNA and DNA synthesis

This mineral has been in the focus of the numerous studies conducted by Dr.  for 15 years. In her latest addition of her book,  it is said that magnesium deficiency triggers or causes issues in 22 medical areas, including:

• Diabetes
• Blood clots
• Migraine
• Asthma
• depression
• Fatigue
• Anxiety and panic attacks
• Tooth decay
• Osteoporosis
• Liver disease
• Heart disease
• Cystitis
• Insomnia
• Detoxification
• Kidney disease
• Hypertension
• Bowel diseases
• nerve issues
• Hypoglycemia
• Obstetrics and gynecology (PMS, infertility, and preeclampsia)
• Raynaud’s syndrome
• Musculoskeletal conditions (fibromyalgia, cramps, chronic back pain, etc.)

The early symptoms of magnesium deficiency include weakness, headaches, appetite loss, nausea, and fatigue.
If this issue continues for a longer period of time, one experiences seizures, coronary spasms, personality changes, numbness and tingling, abnormal heart rhythms, and muscle cramps and contractions.
The Role of Magnesium in Diabetes, Cancer, and More diseases
Numerous studies have found that magnesium can be of great help in the prevention of chronic diseases.
Namely, researchers have discovered its properties to support the proper function of the metabolism,—specifically in terms of insulin sensitivity, glucose regulation, and protection from type 2 diabetes.
Its increased intake lowers the risk of impaired glucose and insulin metabolism and slows the progression from pre-diabetes to diabetes in middle-aged Americans.

According to researchers “Magnesium intake may be particularly beneficial in offsetting your risk of developing diabetes if you are high risk.”

Moreover, higher magnesium levels have also been linked to a higher bone mineral density in both men and women. One study found a link between magnesium in drinking water and a lower risk of hip fractures.

This mineral can also lower the risk of cancer. The study which found that higher intakes of dietary magnesium led to a lower risk of colorectal tumors.

The meta-analysis showed that every 100-mg increase in magnesium intake lowered the risk of colorectal tumor by 13 percent, and the risk of colorectal cancer by 12 percent.

The researchers believe this is due to the property of magnesium to reduce insulin resistance, which might have a positive impact on the development of tumors.

Factors that affect Your Magnesium Levels
Magnesium is found in seaweed and green leafy vegetables like spinach and Swiss chard in high levels, and other rich sources of the mineral include avocados, beans, nuts, and seeds, like pumpkin, sunflower, and sesame seeds. Yet, most foods lack it along with other minerals, as, according to Dr. :
“Magnesium is farmed out of the soil much more than calcium… A hundred years ago, we would get maybe 500 milligrams of magnesium in an ordinary diet. Now we’re lucky to get 200 milligrams.”

The uptake and use of minerals in numerous foods are depleted by herbicides, such as glyphosate, which act as chelators, so we cannot easily find magnesium-rich foods. Moreover, this mineral is additionally depleted by cooking and processing.

Some foods also affect its absorption. The excessive alcohol intake interferes with your body’s absorption of vitamin D, which is helpful for magnesium absorption.

The excess intake of sugar makes the body excrete magnesium through the kidneys, “resulting in a net loss,” in the words of Dr.
Lower magnesium levels might also be a result of:

• Excessive intake of soda or caffeine
• An unhealthy digestive system, which damages the ability of the body to absorb magnesium (Crohn’s disease, leaky gut, etc.)
• Menopause
• Some medications, like diuretics, corticosteroids (prednisone or Deltasone), antacids, certain antibiotics (like gentamicin and tobramycin), and insulin
• Older age (the elderly are more prone to magnesium deficiency as absorption decreases with age, and they also use more medications. )

Furthermore, when trying to increase magnesium levels in your body, you need to consider calcium, vitamin D3, and vitamin K2 as well, as they all function synergistically with one another. For example, excessive levels of calcium without the counterbalance of magnesium might cause heart attack and sudden death, for instance.

Also, research on the Paleolithic or caveman diet found that the ratio of calcium to magnesium in the diet that the human bodies evolved to eat is 1-to-1, and our modern diets have a higher ratio, about  3.5-to-1.

In case your calcium levels are high, but you lack magnesium, you will experience issues like muscle spasms, and heart problems. 

According to Dr.  “What happens is, the muscle and nerve function that magnesium is responsible for is diminished. If you don’t have enough magnesium, your muscles go into spasm. Calcium causes muscles to contract. If you had a balance, the muscles would do their thing. They’d relax, contract, and create their activity.”

You should also consider the amounts of vitamins K2 and D. Their misbalance is one of the reasons why calcium supplements have been linked to the increased risk of heart attacks and stroke, and why some people experience vitamin D toxicity.

This might also be a result of the deficiency of vitamin K2 which needs to keep calcium in its appropriate place, and its low levels lead to the accumulation of calcium in the wrong places, such as the soft tissue.

Moreover, if you take high amounts of vitamin D supplements without enough K2 and magnesium, you might experience vitamin D toxicity and magnesium deficiency symptoms, including inappropriate calcification that damages the heart.

One of the best ways to increase your magnesium levels is to juice your greens. If you decide to take supplements, there are numerous types of magnesium supplements, as it needs to be bound to another substance. This second substance affects its absorption and bioavailability as well as its health benefits.

Ones of the best ones you can use are magnesium threonate and citrate, as they penetrate cell membranes, including the mitochondria, and boost the energy levels. Plus,  they penetrate the blood- brain barrier and boost memory, treat and prevent dementia.

The “bowel test “ is the best way to see if you are taking too much magnesium. 

According to Dr.:“The best way to tell if you are getting enough magnesium is the “bowel test”. You know when you have too much magnesium when your stools become loose. This, in fact, may be a blessing for people with constipation… [which] is one of the many ways magnesium deficiency manifests.”

These are some other magnesium supplement types you can use:

• Magnesium oxide, which is a non-chelated type of magnesium, and is bound to an organic acid or a fatty acid. It has 60 percent magnesium, but its use might lead to stool softening properties
• Magnesium glycinate is a chelated form of magnesium, and it offers the highest levels of absorption and bioavailability.
• Magnesium citrate is the combination of magnesium with citric acid. It is cost effective, well absorbed, but might act as a laxative
• Magnesium taurate is a mix of magnesium and taurine, an amino acid, which calms the body and mind.
• Magnesium threonate has a superior ability to penetrate the mitochondrial membrane, and is the newest alternative, but offers promising effects and might become the best magnesium supplement on the market
• Magnesium chloride/Magnesium lactate has only 12 percent magnesium, but better absorption than others
• Magnesium carbonate has antacid properties and has 45 percent magnesium
• Magnesium sulfate/Magnesium hydroxide (milk of magnesia) supplements are typically used as laxatives, so make sure you use them as directed.

Epsom salt baths or foot baths are a miraculous way to raise your magnesium levels. Epsom salt is a magnesium sulfate that the skin absorbs quickly. You can also use magnesium oil for topical application and absorption.

However, always make sure you avoid supplements which contain magnesium stearate, as it is common, but potentially harmful additive.

 this is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.   
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HEALTH BENEFITS OF VITAMIN K

Vitamins are essential micro-nutrients which the body requires, though in small amounts, for optimal health. They play a crucial role in keeping our body healthy and disease free.One such vitamin is vitamin K, which is essential for optimal blood clotting process, and also has multiple other benefits. More details about the functions, benefits and sources are listed below.
Functions/Benefits:

1. Vitamin K is actually a group of vitamins and has K1, K2, and K3. The functions and benefits accordingly will depend on the actual chemical being referred to.
2. These are fat soluble vitamins and therefore absorption is better when something fatty is eaten along with it
3. Vitamin K1 or phyloquilline reaches the liver and is essential for blood clotting. Reduced levels of vitamin K can lead to uncontrolled bleeding, but this is very rare in adults. Newborns can have this problem, and therefore, it is common to give them a one shot of vitamin K injection.
4. Vitamin K2 is produced by gut bacteria and reaches blood vessel walls and bones. It prevents hardening and calcification of arteries, which is the main cause of heart disease.
5. It helps in improving calcium and other mineral concentration in the bones and makes the matrix strong. It can be used in osteoporosis to reverse and control bone loss. It can also be used to heal fractured bones.
6. It slows the growth of cancer cells and can be used to stabilise cancer. It has been shown to improve multiple forms including hepatocellular, prostate, colon, and oral cancer.
7. It is beneficial in controlling Alzheimer’s disease and improves memory loss in ageing people
8. It improves insulin action and therefore prolongs onset of type 2 diabetes.
9. It has been shown to have antioxidant properties (as most other vitamins) and also helps in reducing toxin buildup
10. It is good for skin health and can help control bruising and dermatitis.

Sources:
Vitamin K is found naturally in many foods and the daily dose required for an adult is about 120 to 150 mcg/day. Therefore supplementation is usually not required.
Leafy green vegetables including spinach, okra, cabbage, beans broccoli, and asparagus

1. Fermented foods like yoghurt
2. Soybean in all forms including medium cooked as well and Japanese diet uses boiled, fermented soybean called natto, which contains tremendous amount of vitamin K
3. Nuts, such as cashews, almonds, walnuts, are a good source
4. Strawberries, grapes, prunes, and apples 
5. Seafood such as salmon and shrimp contain good amount to col heart attack and stroke..
6. Meat (duck, beef, chicken, and lamb)

Supplements are to be avoided, especially in pregnant and/or nursing mothers and people with a history of stroke, heart disease, heart attack and blood clotting problems.

this is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.   
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https://gseasyrecipes.blogspot.com. feel free to view for easy, simple and healthy recipes    
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New blood test detects deadly calcium deposits

A new test could identify individuals who are likely to develop 

potentially deadly calcium deposits in their tissues and blood vessels, a precursor to chronic kidney disease (CKD).

Heart disease is the number one killer of patients with CKD and vascular calcification is thought to play a major role in it. Such patients often have abnormally high blood calcium levels due to their compromised kidney function and the effects of commonly used medications.

Currently, physicians have no tools to determine an individual’s calcification risk, the Journal of the American Society of Nephrology reports.

Researchers who developed the pioneering new assay, have found that both the blood of mice deficient in a protein that inhibits calcification and the blood of CKD patients on dialysis had a reduced ability to inhibit calcification. Blood from healthy volunteers did not.

 This test may identify patients at risk for the development of calcification, may become an important tool for identifying and testing calcification inhibitors, and may provide the basis for treatment monitoring in patients who receive such inhibitors.