Boron - Sources, Health Benefits

Important Sources of Boron

Fruits like apples, oranges, red grapes, pears, plums, kiwis , sultanas, dates, as well as certain vegetables- avocado, soybeans, and nuts are rich sources of boron.  Chickpeas, borlotti beans, hazelnuts, currants, peanut butter, red kidney beans, tomato, lentils, olive, onion, potato, wine, and beer are also notable sources of this essential mineral.

1. Increases concentration and brain function
Research shows low levels of boron can contribute to a sluggish brain, poor cognitive development, and trouble learning or retaining information. Boron is often thought of as a" brain nutrient" because it helps with task performance, better motor control, attention and short-term memory.

2. Arthritis
Boron plays an important role in integrating calcium into the joint's cartilage, which helps prevent joint deterioration, and worsened arthritis pain. Research shows that people with lower boron concentrations in their bones and synovial fluid experience higher rates of arthritis than those with higher levels.

3. Strengthens bones
Boron uses also include the ability to prevent bone loss by facilitating calcium, the main mineral involved in bone mineralization, directly into the bones where it helps prevent porous and weak bones from developing.

4. Balances hormones
As a mineral that balances levels of sex hormones in both women and men, including estrogen and testosterone, boron is useful for reducing PMS and menopause symptoms, as well as increasing fertility.

5.Promotes Healthy Muscle Mass
Certain vitamins and minerals are better absorbed and utilized by the body when boron levels are higher, which is important for building muscle, fat-burning and preventing pain by recovering muscle tissue tears following exercise. And because boron promotes healthy testosterone production, it might lead to higher energy levels and quicker strength gains.

6. Prevents and treats yeast infections
Boron is an active ingredient in tablets used  to treat yeast infections in women. Boron, in the form of boric acid, is used as a natural alternative to messy, over the counter yeast infection medicines or creams. Boric acid is considered safe and effective when inserted into the vagina to speed up healing.

7. Heals skin and prevents infection
Boron contains astringent properties that prevent or treat infections on the skin, so it's useful for lowering redness, inflammation, pain and other signs of irritation. For the same reason, some people also use boron as a natural eye wash to help kill bacteria within the eyes that can lead to sties and other infections.

8. Fights diabetes
Animal studies show low levels of boron can increase physiological effects tied to diabetes, including changes in blood glucose levels and triglyceride concentrations. It appears that boron helps with the metabolism of carbohydrates and the production of insulin from the pancreas that better controls stable blood sugar levels.

9.Enhances Testosterone Levels

Boron is able to enhance the testosterone level in males; this quality is increasingly taken advantage of by male bodybuilders and athletes. Although some weightlifters prefer to take its supplements to enhance their testosterone levels, there has been no concrete evidence or explanation of the mechanism by which it helps to make them any more successful.

10.Promotes Embryonic Development

Boron appears to be essential for reproduction and the development of the fetus, although not much information is available on this property, the research is ongoing.

11. Prevents Post-menopausal Osteoporosis

Boron can ease the symptoms such as hot flashes and night sweats that are typically associated with menopause, and it ensures that the mineral level remains at appropriate levels since post-menopausal women often suffer from hormonal imbalances that can skew many of the body’s important systems.

12.Treats Cancer

Boron neutron capture agents are used for cancer therapy and in the development of strong enzyme inhibitors. Its compounds are also used as antibody mimics that can easily identify biologically important saccharides.

13. Proper Cell Membrane Function

It plays an important role in maintaining cellular and organ membrane functions and in stabilizing the hormone receptors so the bodily processes go smoothly.

14. Prevents Blood Clots

It is believed that boron can influence some of the blood clotting factors in the body. However, more studies need to be done to authenticate this finding, which would make it a major ally in the fight against heart disease.

15. Lowers Plasma Lipid Levels

Boron helps reduce lipid accumulation and enables the removal of cholesterol through various means, thereby reducing the chances of developing conditions like atherosclerosis and blood clots, and protecting the body against stroke and heart attack.

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Testicular cancer responds better to chemotherapy than other cancers

Why is testicular cancer so responsive to chemotherapy, even after it metastasizes? It's because of the stem cells, according to a recent study.

Defining why testicular cancers are so susceptible to chemotherapy could eventually provide insights for treating other, more resistant cancers.

The researchers' study also helped confirm that risk for testicular cancer is determined in utero. The research offers some evidence to support a hypothesis that, in humans, testicular cancers are initiated during embryonic development and lay dormant for 18 to 35 years.

"The study provides new insights into the basis for the responsiveness of testicular cancer to chemotherapy, which has always been an intriguing observation, but the basis for it was not clear," said senior author.

Most types of tumors contain distinct populations of cells. A small fraction of these are stem cells, which have the ability to grow new tumors from a single cell and - in most cancers - are extremely resistant to therapy. Often, other types of tumor cells are killed off during treatment, but cancer stem cells survive, then drive relapse by re-growing new tumors.

But "when testicular cancer stem cells are exposed to chemotherapy, those stem cells are actually more sensitive to it than other cells in the tumor," the author said. The fact that stem cells in testicular cancer are so sensitive to treatment explains why therapy is more effective overall, he said.

In the study, the researchers created a mouse model that, for the first time, can accurately mimic the properties of testicular cancers found in humans. In particular, the engineered mice used in the study develop cancers with the strongest expression of stem cell markers reported to date. The mouse model accurately duplicates realistic tumor characteristics, such as the rate of tumor growth and the ability to give rise to several different tumor cell types.

While other cancers are known as diseases of the elderly, testicular cancers generally strike between the ages of 18 and 40, with rates dropping in older men. Using the mouse model, the researchers reported that germ cells become susceptible to developing into testicular cancer only during a restricted period of embryonic development. As they age, they become resistant to transformation.
Future work may provide clues for treating other cancers if researchers can identify what features of the testicular cancer stem cells make them responsive to chemotherapy and compare those features in other tumor types, he said.

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Vitamin E deficiency may affect mental health of babies

Lack of Vitamin E in babies when they are in the womb can increase a risk of developing impairments in mental skills such as learning and metabolic problems, a research has showed.

The study is conducted on zebrafish as their neurological development is similar to that of humans. The result showed that vitamin E- deficient embryos of zebrafish had more deformities and greater incidence of death as well as altered DNA methylation status through five days after fertilisation - the time it takes for a fertilised egg to become a swimming zebrafish.

However, even after being fed with vitamin E-adequate diet, after their birth, these fish failed to learn and were found afraid.
Although "they managed to get through the critical period to get the brain formed, they were stupid and didn't learn and didn't respond right", said a researcher.

As a result of vitamin E deficiency, the brains of these embryos' continued to lack choline and glucose and simply did not develop correctly, she added.

The deficiency can aggravate in women of child-bearing age who avoid high-fat foods and may not have a diet rich in oils, nuts, and seeds, which are among the foods with the highest levels of vitamin E, an antioxidant necessary for normal embryonic development in vertebrates, the researchers explained.

Further, the Zebrafish with the deficiency in Vitamin E also had metabolic defects and indications of mitochondrial damage.
"They had so much oxidative damage they essentially had a screwed-up metabolism. These outcomes suggest embryonic vitamin E deficiency in zebrafish causes lasting impairments that aren't resolved via later dietary vitamin E supplementation," she said.

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