Novel technique could provide early lung cancer diagnosis

Researchers have developed a new technique that has the potential to identify specific lung cancer markers at the earliest possible stage in a convenient and reusable way.

The new technique could create a highly sensitive graphene biosensor with the capability to detect molecules of the most-common lung cancer bio-markers.

In addition, the new biosensor design could revolutionise the existing electronic nose (e-nose) devices that identify specific components of a specific vapour mixture — a person’s breath — and analyses its chemical make-up to identify the cause.

“The new biosensors which we have developed show that graphene has significant potential for use as an electrode in e-nose devices.

“For the first time, we have shown that with suitable patterning graphene can be used as a specific, selective and sensitive detector for bio-markers,” said a researcher.

With further development of the devices, a cheap, reusable and accurate breath test for early-stage detection of lung cancer can become a reality, the researchers added in a paper published recently.

Lung cancer is one of the most common and aggressive cancers, killing around 1.4 million people worldwide each year.

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Portable cancer detectors?

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 A thin, stretchable film that coils light waves like a Slinky could lead to a portable smart phone-sized device for more precise, less expensive monitoring for cancer survivors, scientists say.


The film provides a simpler, more cost-effective way to produce circularly polarised light, an essential ingredient in the process that could eventually provide an early warning of cancer recurrence. "More frequent monitoring could enable doctors to catch cancer recurrence earlier, to more effectively monitor the effectiveness of medications and to give patients better peace of mind," said Nicholas Kotov of the University of Michigan.