Friday, November 01, 2019

Getting measles 'resets' the body's immune system

Measles, the contagious childhood disease that is once more on the rise globally, is more harmful than previously thought.

A new analysis of 77 un-vaccinated children from the Netherlands carried out by an international team of researchers led by scientists at Harvard has found that the virus erases the body's memory of previous pathogens effectively wiping its immunity memory.


The virus eliminated between 11 and 73 percent of the children's protective antibodies, blood proteins responsible for "remembering" previous encounters with disease, the team wrote in the journal Science on Thursday.

This left some of the children with immunity close to that of a newborn baby.

"It sort of resets your immune system back to sort of a more naive state," the epidemiologist and coauthor told.

In order to rebuild their defenses, they will need to be exposed to numerous pathogens as they were in their infancy, he added.

To validate their result, the team then carried out experiments on macaque monkeys, with the animals losing 40-60 percent of their protective antibodies.

"The virus is much more deleterious than we realized, which means the vaccine is that much more valuable," said study coauthor.


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Saturday, October 22, 2016

Now, study finds a way to reduce jet lag

Reducing oxygen levels in an aeroplane cabin may help combat jet lag in travelers, suggests a new study which found that variation in oxygen levels can reset circadian clocks of mice and help them adapt eating, sleeping and running habits to the new time faster.

Lead author Gad Asher, scientist at the Weizmann Institute of Science in Israel, and his colleagues studied that changing the concentration of oxygen in cells by just 3%, twice a day, will synchronise mouse cells to a circadian rhythm. They suspected protein HIF1a was the link between oxygen and the circadian clock because HIF1a plays both a role in oxygen homeostasis in cells.

They found that cells with low HIF1a levels will not synchronise in response to oxygen variations. "It was extremely exciting to see that even small changes in oxygen levels were sufficient to efficiently reset the circadian clock," said Asher.

Researchers further explored oxygen's effect on circadian rhythms with jet lag experiments. Just like humans, mice are prone to jetlag. Mice were first left to eat, sleep and run on their wheels in air-controlled environments. Altering oxygen levels alone did not change their circadian rhythms but once mice experienced a six-hour jump ahead in daylight hours, varying oxygen levels could help them adapt their eating, sleeping and running habits to the new time faster.


this is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.


https://gscrochetdesigns.blogspot.com. one can see my crochet creations
https://gseasyrecipes.blogspot.com. feel free to view for easy, simple and healthy recipes

https://kneereplacement-stickclub.blogspot.com. for info on knee replacement

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