Now, study finds a way to reduce jet lag
Reducing oxygen levels in an aeroplane cabin may help combat jet lag in
travelers, suggests a new study which found that variation in oxygen
levels can reset circadian clocks of mice and help them adapt eating,
sleeping and running habits to the new time faster.
Lead author Gad Asher, scientist at the Weizmann Institute of Science in Israel, and his colleagues studied that changing the concentration of oxygen in cells by just 3%, twice a day, will synchronise mouse cells to a circadian rhythm. They suspected protein HIF1a was the link between oxygen and the circadian clock because HIF1a plays both a role in oxygen homeostasis in cells.
They found that cells with low HIF1a levels will not synchronise in response to oxygen variations. "It was extremely exciting to see that even small changes in oxygen levels were sufficient to efficiently reset the circadian clock," said Asher.
Researchers further explored oxygen's effect on circadian rhythms with jet lag experiments. Just like humans, mice are prone to jetlag. Mice were first left to eat, sleep and run on their wheels in air-controlled environments. Altering oxygen levels alone did not change their circadian rhythms but once mice experienced a six-hour jump ahead in daylight hours, varying oxygen levels could help them adapt their eating, sleeping and running habits to the new time faster.
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Lead author Gad Asher, scientist at the Weizmann Institute of Science in Israel, and his colleagues studied that changing the concentration of oxygen in cells by just 3%, twice a day, will synchronise mouse cells to a circadian rhythm. They suspected protein HIF1a was the link between oxygen and the circadian clock because HIF1a plays both a role in oxygen homeostasis in cells.
They found that cells with low HIF1a levels will not synchronise in response to oxygen variations. "It was extremely exciting to see that even small changes in oxygen levels were sufficient to efficiently reset the circadian clock," said Asher.
Researchers further explored oxygen's effect on circadian rhythms with jet lag experiments. Just like humans, mice are prone to jetlag. Mice were first left to eat, sleep and run on their wheels in air-controlled environments. Altering oxygen levels alone did not change their circadian rhythms but once mice experienced a six-hour jump ahead in daylight hours, varying oxygen levels could help them adapt their eating, sleeping and running habits to the new time faster.
this is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.
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Labels: aeroplane, circadian rhythm, jet lag, oxygen levels, reducing, resets
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