Medications That Don't Mix With Exercise

When it comes to mixing exercise with medication, the latter can sometimes affect the former. Therefore, if you’re using medications, you really need to know all of their potential effects, good and bad, on you. Here’s a quick scoop on which meds could be clashing with your cardio.  

 

1. Beta-Blockers

What Are They? This group of medications, also known as beta-adrenergic blocking agents, are used to treat high blood pressure and are also commonly prescribed for conditions such as migraines and glaucoma. 

 

Beta-blockers lower the heart rate, which is the opposite of what exercise induces – an increased heart rate. Therefore, combing both gives your body conflicting messages, and people tend to get fatigued very quickly. 

 

What to Do 

While it’s always a good idea to speak to your doctor or pharmacist about how to accommodate exercise while on beta-blockers, you should consider asking if you really need to be taking them. In some cases it is and in other cases, there are better alternatives. For example, acupuncture has been found to help some migraine sufferers. If they are necessary, you should begin with as low a dose as possible to see if your ability to exercise is adversely affected.

2. Pain Medications 

What Are They? 

 There are two types of pain medications: acetaminophen, which is an alternative to aspirin for pain relief, and ibuprofen, which treats swelling and inflammation as well as pain. 

 

Pain is usually a signal of tissue injury, so overusing pain medication can be a concern. For example, if you have a sprained ankle and you take a lot of medication to get through the pain, that can be bad because the sprain won’t heal adequately and you might re-injure it. 

 

There’s also some concern about non-steroidal anti-inflammatory drugs such as ibuprofen, Advil Motrin, and Aleve. These can cause fluid retention, which isn’t particularly kind on the kidneys and puts more stress on the cardiovascular system. 

 

What to Do 

Firstly, if you have a sprained ankle, let your body rest and heal rather than mask the pain with medications so that you can continue exercising. If it’s a milder pain that’s afflicting you and you’re using ibuprofen or Motrin, try not to take the medication for more than a week. If you need longer pain relief, switch to an acetaminophen medication to treat it and avoid that fluid retention stress.  

 

3. Antidepressants

What Are They? 

While there are many medications that trigger sleepiness, antidepressants are the more common ones as they alter the chemical balance in the brain to help stabilize and improve your mood. Drowsiness and fatigue are usually at their worse during the first few weeks of taking them. Furthermore, they also have the added side effect of weight gain. 

 

What to Do 

There are many different types of antidepressants and if yours causes a lot of drowsiness, talk to your doctor about taking alternative antidepressants. Also, starting off with a lower dosage of a new antidepressant can help the sleepiness factor.  

 

4. Antihistamines 

What Are They?

Drowsiness is a common side effect of antihistamines, especially older generation medications such as Chlor-Tripolon and Benadryl. Antihistamines block or decrease histamine, which is triggered by an allergic reaction such as coming into contact with pollen or animal fur. When you’re taking antihistamines your alertness can be affected. Therefore, for example, if you’re a runner and you take antihistamines that make you drowsy, you can misstep and become injured. 

 

What to Do 

There are newer generations of antihistamine medications such as Alegra, Claritin, and Reactin that don’t cause the same level of drowsiness, if at all. However, if you prefer the older antihistamines, time your medication well. The older ones are usually shorter-acting, so they might last only four hours and once that drowsiness has worn off, you can exercise.

This is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.   

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Asprin may help reduce harmful effects of air pollution on lungs

The findings published in the American Journal of Respiratory and Critical Care Medicine highlight that nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin may lessen the effects of air pollution exposure on lung function.

Researchers analyzed a subset of data collected from a cohort of 2,280 male veterans from the greater Boston area who were given tests to determine their lung function. The average age of participants was 73 years.

 

The researchers examined the relationship between test results, self-reported NSAID use, and ambient particulate matter (PM) and black carbon in the month preceding the test, while accounting for a variety of factors, including the health status of the subject and whether or not he was a smoker.

They found that the use of any NSAID nearly halved the effect of PM on lung function, with the association consistent across all four weekly air pollution measurements from same-day to 28 days prior to the lung function test.

Because most of the people in the study cohort who took NSAIDs used aspirin, the researchers say the modifying effect they observed was mainly from aspirin, but add that effects of non-aspirin NSAIDs are worthy of further exploration.

Researchers speculate that NSAIDs mitigate inflammation brought about by air pollution.
“It is still important to minimize our exposure to air pollution, which is linked to a host of adverse health effects, from cancer to cardiovascular disease” said first and corresponding author.

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Taking pain killers during flu may up heart attack risk

Taking pain relievers during a  cold or flu like illness may increase the risk of heart attack, a new study of 10,000 patients has warned.
Researchers at National Taiwan University Hospital in Taiwan suggest physicians and patients should use caution when prescribing or taking the medications, known as nonsteroidal anti-inflammatory drugs (NSAIDs), to ease symptoms of acute respiratory infections.
In an observational study, researchers analysed claims from Taiwan's National Health Insurance Programme over a seven-year period (2005-2011), including data from nearly 10,000 patients who were hospitalised for a heart attack.
The goal was to study whether two potential cardiac risk factors - an acute respiratory infection, such as a cold or influenza, and NSAID use - have a combined, joint effect on heart attack risk.
Researchers compared each patients' own risk for heart attack over time, across episodes of respiratory illness and NSAID use. They found a stronger association with a heart attack when both risk factors were present.
Using the pain relievers during an acute respiratory infection was associated with a 3.4-fold increased risk for a heart attack, with 7.2 times greater risk when patients received the pain-relieving medication intravenously in the hospital, compared to times when patients had neither of the risk factors.
The heart attack risk when patients with an acute respiratory illness were not taking an NSAID was 2.7 times greater, while the risk was 1.5 times greater when individuals took the drugs and did not have an infection.
Previous research has implicated respiratory infections and some NSAIDs as potential triggers for heart problems, but earlier studies have examined these risk factors only separately.
"Physicians should be aware that the use of NSAIDs during an acute respiratory infection might further increase the risk of a heart attack," said study author Cheng-Chung Fang, from National Taiwan University Hospital.
Patients seeking relief from cold and flu symptoms should consult with their doctor or a pharmacist before using NSAIDs, said Fang. 

 Another commonly used pain reliever, acetaminophen, which eases pain in a different way than NSAIDs do, may be a safer alternative, in terms of cardiac risk, for relief from cold and flu symptoms, although the drug was not evaluated in the study.


While the study's findings suggest an association between NSAID use, acute respiratory infections, and increased cardiac risk, they do not prove a cause-and-effect relationship.

Additional research is needed to clarify the apparent combined effect on risk and how the effect might be managed.

The study was published in the Journal of Infectious Diseases.

 this is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.
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Pill for Menstrual Pain Restores Memory in Mice with Alzheimer's

A surprising discovery has been made in the treatment of Alzheimer's disease. An anti-inflammatory drug used to treat menstrual pain completely reversed memory symptoms in mice with Alzheimer's.

The drug, called mefenamic acid, is a so-called non-steroidal anti-inflammatory drug, or NSAID, used to relieve menstrual cramps.

In experiments with mice specially bred to have Alzheimer's symptoms, the rodents predictably developed memory problems over time.

Ten of the Alzheimer's mice were treated for one month with mefenamic acid that was contained in tiny pumps implanted under their skin. Ten other mice with memory difficulties were injected with pumps of a placebo, or inactive substance.

The rodents were placed in maze to train them to get around the obstacles.

In a Skype interview, Mike Daniels, who participated in the research at the University of Manchester in Britain, said "We tried to train the mice once they had Alzheimer's disease. The Alzheimer's mice are untrainable. They cannot learn that maze."

But the results in the treated mice were stunning.

"What was just amazing is that this drug seemed to render the mice completely normal,” Daniels said. “It's something we haven't really seen before, but there needs to be a lot more work done to really confirm whether this is real.”

Targeting inflammation
The findings were published in the journal Nature Communications. The research was led by David Brough of the University of Manchester.

Daniels said brain-imaging shows a lot of harmful inflammation in the brains of Alzheimer's patients.

Researchers believe mefenamic acid targets an inflammatory pathway called NLRP3, reducing inflammation.

Scientist found that no other NSAIDS — including ibuprofen, which is commonly taken for pain — reduced the brain inflammation.

Whether it works in patients at all stages of Alzheimer's — from people with mild cognitive impairment to those who are severely affected — is difficult to say, according to co-author Jack Rivers-Auty.

"Maybe, if this was translated into the clinic, we would definitely want to put it into people at the early stages of the disease to try to slow the progress or stop the progress of the disease," said Rivers-Auty, "rather than taking the ambitious aim of taking someone who fully has Alzheimer's disease, has all the symptoms — incredible memory loss, incredible cognitive impairment — and trying to reverse those symptoms. That might be very difficult."

Mefenamic acid already has been approved by regulators so, after further testing, it could reach the market relatively quickly as a treatment for Alzheimer's disease.

 this is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.
https://gscrochetdesigns.blogspot.com. one can see my crochet creations
https://gseasyrecipes.blogspot.com. feel free to view for easy, simple and healthy recipes

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