Thursday, March 17, 2022

Medications That Don't Mix With Exercise

When it comes to mixing exercise with medication, the latter can sometimes affect the former. Therefore, if you’re using medications, you really need to know all of their potential effects, good and bad, on you. Here’s a quick scoop on which meds could be clashing with your cardio.  
 
1. Beta-Blockers

What Are They? This group of medications, also known as beta-adrenergic blocking agents, are used to treat high blood pressure and are also commonly prescribed for conditions such as migraines and glaucoma. 
 
Beta-blockers lower the heart rate, which is the opposite of what exercise induces – an increased heart rate. Therefore, combing both gives your body conflicting messages, and people tend to get fatigued very quickly. 
 
What to Do 
While it’s always a good idea to speak to your doctor or pharmacist about how to accommodate exercise while on beta-blockers, you should consider asking if you really need to be taking them. In some cases it is and in other cases, there are better alternatives. For example, acupuncture has been found to help some migraine sufferers. If they are necessary, you should begin with as low a dose as possible to see if your ability to exercise is adversely affected.
2. Pain Medications 
What Are They? 
 There are two types of pain medications: acetaminophen, which is an alternative to aspirin for pain relief, and ibuprofen, which treats swelling and inflammation as well as pain. 
 
Pain is usually a signal of tissue injury, so overusing pain medication can be a concern. For example, if you have a sprained ankle and you take a lot of medication to get through the pain, that can be bad because the sprain won’t heal adequately and you might re-injure it. 
 
There’s also some concern about non-steroidal anti-inflammatory drugs such as ibuprofen, Advil Motrin, and Aleve. These can cause fluid retention, which isn’t particularly kind on the kidneys and puts more stress on the cardiovascular system. 
 
What to Do 
Firstly, if you have a sprained ankle, let your body rest and heal rather than mask the pain with medications so that you can continue exercising. If it’s a milder pain that’s afflicting you and you’re using ibuprofen or Motrin, try not to take the medication for more than a week. If you need longer pain relief, switch to an acetaminophen medication to treat it and avoid that fluid retention stress.  
 
3. Antidepressants
What Are They? 
While there are many medications that trigger sleepiness, antidepressants are the more common ones as they alter the chemical balance in the brain to help stabilize and improve your mood. Drowsiness and fatigue are usually at their worse during the first few weeks of taking them. Furthermore, they also have the added side effect of weight gain. 
 
What to Do 
There are many different types of antidepressants and if yours causes a lot of drowsiness, talk to your doctor about taking alternative antidepressants. Also, starting off with a lower dosage of a new antidepressant can help the sleepiness factor.  
 
4. Antihistamines 
What Are They?
Drowsiness is a common side effect of antihistamines, especially older generation medications such as Chlor-Tripolon and Benadryl. Antihistamines block or decrease histamine, which is triggered by an allergic reaction such as coming into contact with pollen or animal fur. When you’re taking antihistamines your alertness can be affected. Therefore, for example, if you’re a runner and you take antihistamines that make you drowsy, you can misstep and become injured. 
 
What to Do 
There are newer generations of antihistamine medications such as Alegra, Claritin, and Reactin that don’t cause the same level of drowsiness, if at all. However, if you prefer the older antihistamines, time your medication well. The older ones are usually shorter-acting, so they might last only four hours and once that drowsiness has worn off, you can exercise.


This is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.   

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Thursday, March 12, 2020

Aspirin may lower risk of ovarian cancer

Taking a low-dose of aspirin daily may help women lower their risk of developing ovarian cancer by 23 per cent, suggests a new study.

Ovarian cancer is the most fatal gynaecological cancer, largely due to lack of early detection strategies and is believed that the inflammation that occurs during ovulation plays a role in the development of this cancer.

Aspirin is thought to lower cancer risk by reducing inflammation.

The findings, led by researchers from H. Lee Moffitt Cancer Centre and Research Institute in the US, showed that low-dose aspirin use was associated with a lower risk of ovarian cancer while standard-dose aspirin use increased the risk, their findings revealed.
Conversely, women who took non-aspirin anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil) or naproxen (Aleve) -- at least 10 tablets per week for many years, had an increased risk of developing the disease.

"We're not quite at the stage where we could make the recommendation that daily aspirin use lowers ovarian cancer risk. We need to do more research. But it is definitely something women should discuss with their physician," said Shelley Tworoger, Associate Centre Director from the varsity.

For this study, published in the journal JAMA Oncology, the team analysed data on more than 200,000 women among which 1,054 developed ovarian cancer.

In addition, researchers looked at the participants' use of aspirin (325 milligrams), low-dose aspirin (100 milligrams or less), non-aspirin NSAIDs and acetaminophen.

This is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.     

https://gscrochetdesigns.blogspot.com. one can see my crochet creations  
https://gseasyrecipes.blogspot.com. feel free to view for easy, simple and healthy recipes    
https://kneereplacement-stickclub.blogspot.com. for info on knee replacement
 

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Tuesday, April 09, 2019

Researchers discover new therapy target for drug-induced liver failure

A new research from a mouse study has suggested that treatments that increase levels of the protein thrombospondin-1 could help the liver recover from an overdose of acetaminophen.

According to the research presented at a meeting, Acetaminophen, a commonly used pain reliever, and fever reducer is the leading cause of quickly developing, or acute, liver failure in the United States.

“The only treatment available now for acetaminophen overdose must be administered early before significant liver injury occurs,” said the researcher.

“We are working to identify new drug targets to improve treatment options and reduce the need for liver transplantation, which is often the only option for patients with acute liver failure due to drug toxicity,” he added.

Researchers found that mice with acute liver failure from acetaminophen toxicity had higher levels of thrombospondin-1 than mice with normal liver function.

When they administered acetaminophen to genetically modified mice that lack thrombospondin-1, the liver injury and loss of liver function was more severe compared to unmodified mice.

The researchers also observed impaired liver regeneration and increased cell death in the mice without thrombospondin-1.

“Our study is the first to investigate thrombospondin-1 during acetaminophen toxicity. We were able to identify cell communication pathways that do not work properly during acetaminophen-induced liver injury and thus lead to worse outcomes,” said the researcher.

Next, the researchers plan to give mice different drug treatments that manipulate thrombospondin-1 to find out which treatment might be suited for potential clinical studies.They also plan to examine patients with acetaminophen-induced acute liver failure to determine if their thrombospondin-1 findings from mice hold true in people.

THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.                                    PS- THOSE INTERESTED IN RECIPES ARE FREE TO  VIEW MY BLOG-                                                                                           https://gseasyrecipes.blogspot.com/                                                                                                                                                         FOR INFO ABOUT KNEE REPLACEMENT, YOU CAN VIEW MY BLOG-                                                  https:// kneereplacement-stickclub.blogspot.com/           


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