Researchers find antibody that blocks infection by covid in cell

Researchers have identified a fully human monoclonal antibody that prevents the SARS-CoV-2 (COVID-19) virus from infecting cultured cells.

The discovery, detailed in the journal Nature Communications, is an initial step towards developing a fully human antibody to treat or prevent the respiratory disease COVID-19 caused by the novel coronavirus SARS-CoV-2.

The COVID-19 pandemic has spread rapidly across the globe infecting more than 3.3 million people worldwide and killing more than 235,000 people so far.

This research from Utrecht University, Erasmus Medical Center and Harbour BioMed (HBM) builds on the work they have done in the past on antibodies targeting the SARS-CoV that emerged in 2002/2003.

“Using this collection of SARS-CoV antibodies, we identified an antibody that also neutralizes infection of SARS-CoV-2 in cultured cells,” said study co-lead author Berend-Jan Bosch, Associate Professor at Utrecht University in the Netherlands.

“Such a neutralising antibody has the potential to alter the course of infection in the infected host, support virus clearance or protect an uninfected individual that is exposed to the virus,” Bosch added.

The researchers noted that the antibody binds to a domain that is conserved in both SARS-CoV and SARS-CoV-2, explaining its ability to neutralize both viruses.

This cross-neutralising feature of the antibody is very interesting and suggests it may have potential in mitigation of diseases caused by future-emerging related coronaviruses, Bosch said.

This discovery provides a strong foundation for additional research to characterise this antibody and begins development as a potential COVID-19 treatment.

“The antibody used in this work is ‘fully human,’ allowing development to proceed more rapidly and reducing the potential for immune-related side effects,” said study co-author Frank Grosveld.

Conventional therapeutic antibodies are first developed in other species and then must undergo additional work to ‘humanize’ them, according to the researchers.

The antibody was generated using Harbour BioMed’s H2L2 transgenic mouse technology.

“This is groundbreaking research. Much more work is needed to assess whether this antibody can protect or reduce the severity of disease in humans,” said Dr Jingsong Wang, Founder, Chairman and Chief Executive Officer, Harbour BioMed.

“We expect to advance the development of the antibody with partners. We believe our technology can contribute to addressing this most urgent public health need and we are pursuing several other research avenues,” Wang noted.

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Here is a scientific point of vue of Virus and Vibrations

Here is a very interesting article which shows the urgency of increasing your vibrations while working on you.

"VIBRATE HIGH!

CORONA-VIRUS, like any other virus, is a low-vibration entity with a closed structure of the electromagnetic circuit, with a resonant frequency of about 5.5 Hz to 14.5 Hz. In higher ranges, there is no is not active and, from ranges 25.5 Hz and above, the virus dies. For a person living in high vibrations, it is no more dangerous than acute respiratory infections. The human body whose soul is "healthy" vibrates in higher ranges.

Unfortunately, a lot of people drive in lower vibrations. The reasons can come from various disturbances (fatigue, emotional exhaustion, hypothermia, chronic diseases, fear, blocked emotions, nervous tension, etc.).

The virus in nature, outside the body, is not resistant since the total average frequency resonance of the Earth is today about 27.4 Hz, but there are places where this frequency is lowered, i.e. areas created naturally or artificially (hospitals, prisons, power lines, metro, public electric vehicles, shopping centers, offices, etc.) where the vibrations are less than 20 Hz.

For all those who are in the ego, control and therefore fear, namely in a low vibration, this virus can be more impacting and therefore dangerous.

Example of vibration rate:

• grief gives vibrations from 0.1 to 2 Hz

• fear of 0.2 to 2.2 Hz

• resentment from 0.6 to 3.3 Hz

• irritation from 0.9 to 3.8 Hz

• disturbance from 0.6 to 1.9 Hz

• warm temperament 0.9 Hz

• 0.5 Hz fury flash

• 1.4 Hz anger

• pride 0.8 Hz

• pride (megalomania) 3.1 Hz

• 1.5 Hz neglect

• feeling of superiority 1,9 Hz

• generosity 95 Hz

• thanks 45 Hz

• deep gratitude from 140 Hz and above

• feeling of unity and communion 144 Hz and more

• compassion from 150 Hz and above (and pity is only 3 Hz)

• love to have (Eros, person who understands that love is a good light sensation and a great force, but has not yet learned to love with his heart) vibration 50 Hz

• Love Being (Philae, that a person generates with all his heart to all living beings without exception from 150 Hz and more

• Unconditional universal love (Agape) from 205 Hz and up.

For millennia, the frequency of vibrations (that is, vibrations per second) of our planet was 7.6 Hz. Physicists call it Schumann resonance. Scientists often checked their instruments with it. A man felt comfortable in these conditions, because the vibration frequency of his energy field had the same parameters from 7.6 to 7.8 Hz. However, the Schumann resonance has recently started to increase strongly.

We follow the dynamics:

January 1995: 7.80 Hz

January 2000: 9.30 Hz

January 2007: 9.80 Hz

January 2012: 11.10 Hz

January 2013: 13.74 Hz

January 2014: 14.86 Hz

February 2014: 14.99 Hz

March 2014: 15.07 Hz

April 2014: 15.15 Hz

Even if we consider the situation from the point of view of science, it becomes clear that a person who does not increase his vibrations will soon leave the earth plane in one way or another, and neither the elevated positions nor the accumulated capital will help him/her. You can increase your vibrations by working on yourself, only those who will do emotional work and raise their vibrations will survive.

P.S. All negative emotions close access to a clear conscience. Advice, vibrate high, vibrate love, be love, be in joy, heal your wounds, quickly get rid of your fears, your anger and free yourself from those emotions which lower your vibration. "

Beautiful experiences, beautiful discoveries and transcendences, Have fun and vibrate high!

May Strength, Love, Joy and Fun be with you!

Take care of yourself, see you soon.

 

This is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.     

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Pranayama in The Time of COVID-19: Harvard and Beyond

COVID-19 has brought the focus right back to the Breath, where modern Science believes all things begin and end. Medical practitioners all over the world are finding ways to tackle the virus, which enters, stays and multiplies first in the upper respiratory system, and when fortified, attacks the lower respiratory system.

Scenario 1: Northumbria University Associate Professor Sterghios Moschos is leading research into a device to collect breath samples which could be tested in minutes. If trials show it can detect the virus, its results could be quicker and more reliable than current tests, he says.

His kit is simple. All that you will be asked to do is: 'Please breathe into this'. Current tests mostly use nose and throat swabs because chest samples are only available if the patient coughs up mucus. Data in papers released by Chinese researchers show that the swab method that is being used worldwide right now is not reliable, says Dr Moschos. He believes his device would work better because it tests the breath, which has circulated in the chest.

Scenario 2: A journalist of Mother Jones contacted Loren Rauch, a community ER doctor at Antelope Valley Hospital in Los Angeles, to check the veracity of the claim that “the new coronavirus may not show signs of infection for many days. By the time you have fever and/or cough and go to the hospital, the lung is usually 50 percent fibrosis.”

Rauch replied, “That doesn’t mean anything. Fibrosis is a late scarring process. You may have 50 percent of your lung affected by the virus, causing pneumonia or fluid in your lungs. If you can breathe fine, do not go to the doctor. Only go if you cannot breathe or are very ill.”.

Scenario 3: The anxiety and stress is mounting. Dr John Sharp is a board-certified psychiatrist on the faculty at Harvard Medical School and the David Geffen School of Medicine at UCLA. He has been voted by his peers for inclusion in Best Doctors in America for the past 10 years. On March 12, he posted suggestions on how to beat stress during COVID-19, on the Harvard Medical School website (https://www.health.harvard.edu/blog/coping-with-coronavirus-anxiety-2020031219183).

He says: “Here are some tried and true ways to relax: Yoga. Not a yoga person? No need to start now unless you’d like to try it. Sometimes trying new things and discovering new activities you can benefit from and enjoy can be a welcome, healthy distraction. Meditation. Regular meditation is very calming.”

And finally, controlled breathing. “One simple technique is called square breathing. Visualize your breath traveling along a square. As you follow the instructions to inhale, hold your breath, or exhale, count slowly to three on each side. Try it now. Inhale up the first side of the square. Slowly count one, two, three. Hold your breath across the top. One, two, three. Exhale down the other side of the square. One, two, three. Then hold your breath across the bottom. One, two, three. After a few minutes of this you should be feeling calmer and more centered.”

He is perhaps referring to the nasal expiration and control of breath, with which every single student of yoga is familiar with. To call it 'Square Breathing' is unacceptable. He is essentially talking about:

प्रच्छर्दनविधारणाभ्यां वा प्राणस्य॥३४॥

pracchardana-vidhāraṇa-ābhyāṁ vā prāṇasya ॥34॥

Yoga Sutra, Samadhi Pada, Sutra 1.34

It (Stability) can also be attained through the practice of gradual nasal expiration and control of breath (Translation by James Haughton Woods in his book The Yoga-System of Patanjali)

In India, the Sun’s energy is said to produce and preserve the conditions necessary for life in all living beings. SK Ramachandra Rao in his book Yoga and Tantra in India and Tibet says Yoga techniques emphasise that it is not “consciousness that should be sought to be corrected but the basic vital currents that should be handled in order that the consciousness spontaneously gets expanded, relaxed and deep.”

India has developed a deep and profound system of breathing. Dr Rao writes: “breath alternates during the course of the day between the left nostril (connected with the ida, representing moon, and in effect cooling) and the right nostril (connected with pingala, representing sun, and in effect heating). Normally, breathe passes through the arteries 960 times an hour…During our normal respiration, inhalation is an active process, and exhalation a passive one. Thoughts arise and cease in accordance with the respiratory rate.”

Further, “If breath does not alternate between the nostrils, but continues in one nostril beyond the normal period of an hour and fifty minutes, it is symptomatic of impairment of health, due to either excess of heat or of cold. If the breath moves in and out through single nostril for as long as 24 hours, the derangement of humours is serious; if the condition prevails for two or more days, the illness is grave enough.”

The American born son of Russian Jewish parents, world renowned  violinist Yehudi Menuhin became a serious student of BKS Iyengar, making Yoga a regular feature of his life. Because it was not practical for Menuhin to return constantly to India to have lessons, he took Iyengar with him to Britain, France and Switzerland. Iyengar met and taught some of the most famous artistes and musicians in the world including cellist Jacqueline du Pre. They, like Menuhin, discovered that yoga releases everything (Classic fM)

In his foreword to Iyengar's book Light on Pranayama Menuhin writes: “He (Iyengar) has placed in the hands of the layman…more information, more knowledge and more wisdom in an integrated way than is available to our most brilliant students of conventional medicine, for it is a medicine of health and not of sickness, it is an understanding of the spirit, body and mind that is as healing as it is invigorating.”

He continues: “He teaches us in line with ancient Indian philosophy that life is not only dust to dust, but air to air, that, as with the process of fire, matter is transformed into heat, light and radiation from which we may gather strength. But strength is more than the transformation of matter into other forms of matter, it is the transformation of the whole cycle of air and light into matter and back again.

In fact, it (Pranayama) completes Einstein’s equation of matter and energy and translates it into the human, the living incarnation.”

“Ancient, classical Indian texts, will provide illuminating guidelines to the reconciliation of various practices of medicine from acupuncture to touch and sound therapy to the mutual and reciprocal benefit of them all. It will also teach us to respect those elements which we have treated with such contempt – air, water and light, without which life cannot survive.”

The Upanishads say that prana is the principle of life and consciousness. Prana is the breathe of life and of all living beings in the universe. They are born and live by it and when they die their individual breath dissolves into the Cosmic Breath. And does not bite the dust.

This is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.     

https://gscrochetdesigns.blogspot.com. one can see my crochet creations  
https://gseasyrecipes.blogspot.com. feel free to view for easy, simple and healthy recipes    
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