Obesity poses a higher risk of type 2 diabetes in women, and Chronic
Obstructive Pulmonary Disease (COPD) and chronic kidney disease in men,
said a new study from the University of Oxford.
"The study shows just how harmful carrying excess weight can be to human
health, and that women and men may experience different diseases as a
result," said the study's first author.
To identify additional causes of death made worse by obesity,
researchers performed an analysis that explores cause-and-effect
relationships using genetic data and three measures of obesity from
228,466 women and 195,041 men in the UK Biobank.
Their analysis showed that obesity contributes to a laundry list of
health problems including coronary artery disease, type 1 and 2
diabetes, stroke, chronic obstructive pulmonary disease, lung cancer,
non-alcoholic fatty liver disease, chronic liver disease and kidney
failure.
While obesity causes type 2 diabetes in both women and men, women
experienced a higher risk of type 2 diabetes as compared to men, while
men faced a greater risk of chronic obstructive pulmonary disease and
chronic kidney disease.
"Given the compelling evidence of harm that arises as a consequence of
obesity across a broad range of diseases that result in death, our
findings highlight the critical need for public health measures to stem
the tide of obesity," said a researcher.
Overall, the study found that obesity causes or contributes to the
majority of the leading causes of death worldwide that are not linked to
the infectious diseases.
The impact of obesity, however, manifests differently in men and women.
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