Tuesday, December 03, 2019

Hot weather linked to rise in early childbirth

Hot weather can cause a spike in the number of babies being born early, a phenomenon that may harm infant health and is likely to get worse as temperatures climb due to climate change, scientists said Monday. Researchers in California said an average of 25,000 children were born up to two weeks early during warmer than average periods in the United States between 1969-1988 -- equivalent to 150,000 lost gestational days annually.

While it is not certain why mothers appear to go into labour early as the mercury climbs, the authors of the study published in Nature Research Journals said premature births was an issue to be taken seriously.

"It is very likely that being born earlier will affect child development and have lasting impacts into adulthood, but more research is needed to confirm this," Alan Barreca, from the Institute of the Environment and Sustainability, University of California-Los Angeles.

"Hot weather increases maternal levels of oxytocin, which is a key hormone that regulates labour and delivery. But, the link could be because hot weather causes cardiovascular stress, which might lead to early deliveries," he told AFP.

Barreca and a colleague used estimate shifts in daily birth rates from US counties over a 20-year span, a sample including 56 million births.
 

- 'Very concerned' -

They found that early birth rates increased by five percent on days where the temperature was above 90 degrees Farenheit (32.2 Celsius), accounting for around one out of every 200 births.

With temperatures currently around 1C hotter than pre-industrial averages and set to increase further, Barreca said he was "very concerned" of the potential impacts of greater weather-linked early birth rates in future.

"We predict more than 1 in 100 births will occur earlier than expected in the US by the end of the century," he said.

"That number may seem small, but that's much higher than the risks of getting into a car accident."

He pointed out that while air conditioning was likely to provide mothers with protection during hot weather, the technology was energy-heavy, expensive, and largely absent in developing nations.

"Some families will experience financial stress even if they are able to use more air conditioning during pregnancy, and financial stress is also bad for children," he said.

Andrew Shennan, professor of Obstetrics at King's College London said that while extremes of temperature have long been linked to the risk of premature delivery, the nature of that link was unclear.

"Given the wide variety of temperatures around the world, and that most women have normal pregnancies, this is unlikely to be an important risk factor for any individual," said Shennan, who was not involved in the study.


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Monday, September 23, 2019

Baby gut study finds bacteria different after C-section births

A huge study of babies' stool samples has found key differences between infants born vaginally and via Caesarean section, offering clues about the development of the human immune system, researchers said on Wednesday.

Vaginally born babies got most of their gut bacteria from their mother, but C-section babies did not and had more bacteria linked to the hospital around them, the study found.

It is not clear what impact the difference may have on children's future health, and the findings should not deter women from having C-section births, the scientists leading the work said.

But the so-called "baby biome" project - the world's largest such study - had opened a window on a little-understood stage in the development of human immunity, they added.

"The first weeks of life are a critical window of development of the baby's immune system, but we know very little about it," said a professor who co-led the study.

"We need to follow up ... these babies as they grow to see if early differences in the microbiome lead to any health issues."

The gut microbiome is a complex ecosystem of millions of microbes and is thought by scientists to be important for how the immune system develops.

Previous research has suggested that a lack of exposure to some microbes in early life is implicated in autoimmune diseases such as asthma, allergies and diabetes.

But scientists have not yet been able to work out how important the initial gut microbiome - or "baby biome" - is to future immunity and health, or how a baby's microbiome develops, or what happens to it with different modes of birth.

In this research,  scientists  used DNA sequencing to analyse more than 1,600 gut bacteria samples from 175 mothers and almost 600 babies.


In samples from mothers and from the babies at four, seven and 21 days old, the team found there was a significant difference between the two delivery methods - with vaginally delivered babies having many more health-associated bacteria from their mothers than babies born by Caesarean.

In place of some of the mother's bacteria, the C-section babies had more bacteria typically found in hospitals, the researchers said, and these bugs were also more likely to be drug-resistant.

"At the moment we don't understand the long-term consequences of this," the researcher said at a briefing about the results. "It's clearly complex and we're only just beginning to scratch the surface."


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Monday, March 10, 2014

Giving birth 10 times lowers mom's cancer risk- but that doesn't mean we've to increase the world's population

Amazingly, women who give birth to 10 or more children are at a reduced risk of developing cancer, a new study has claimed.
Researchers examined cancer risk in nearly 5,000 Finish women who gave birth at least 10 times before 2010.
Over a three-decade period, there were 656 cases of cancer in these women, about 200 fewer cases than would be expected based on cancer rates in the general Finnish population, researchers said.
The rate of new cancer cases was 24 per cent lower among women who delivered 10 or more babies compared to those in the general population, they said.
The rate of new cancer cases for breast cancer and gynecological cancers, including ovarian and endometrial cancer (cancer of the uterus lining), was about 50 per cent lower in women with 10 or more deliveries, compared to the general population.
In the study, women who had 10 or more babies were about five years younger when they gave birth to their first child, compared to average Finnish women, said study researcher Dr Juha Tapanainen, of the Department of Obstetrics and Gynecology at Helsinki University Central Hospital.
It's known that becoming pregnant at a young age helps protect against breast cancer, Tapanainen said.
Many women in the new study who had 10 or more children were members of the Laestadian movement, which is part of the Lutheran Church in Finland, researchers said.
Women in this group are similar to average Finnish women in terms of their lifestyle, but their religion prohibits the use of contraceptives, 'LiveScience' reported.
Studies on the effect of hormonal contraceptives on cancer risk have been inconclusive, but some studies suggest that the contraceptives reduce the risk of ovarian and endometrial cancer.
Thus, it's possible that if Laestadian women in the study also took contraceptives, and still had multiple pregnancies, it would even further reduce their risk of these cancers, Tapanainen said.
The study also linked having 10 babies with a reduced risk of basal cell skin cancer, and an increased risk of thyroid cancer. The reason for this link could not be determined.
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