Wednesday, October 09, 2019

Kerala Scientists Have Designed a Low-Cost Bra That Detects Breast Cancer!

Of all forms of cancer, breast cancer has the highest rate of incidence in India. Data says that one in every 22 women develop it.
Sadly, the latest cancer statistics in India states that out of every two women who develop breast cancer, one dies.

Unlike what has been observed across the world, the strata of female population being diagnosed with breast cancer is alarmingly getting younger across both urban and rural settings in India. Breast cancer is increasingly being detected in the 30-40 age group and sometimes, even younger.

Despite the high prevalence of the disease, there are huge, underlying deficits in the procedural as well as infrastructural facilities for breast cancer and that includes not just detection, diagnosis, counselling or treatment but most importantly, awareness across India.

The most common initial course of action for diagnosing and screening of breast cancer is the mammogram test of which radiation is a major concern. In fact, doctors and cancer specialists in India have repeatedly advised mammogram only after the age of 50.

Additionally, the test is not really an economically viable option for everyone, with its costs ranging anywhere between Rs 1,500 to Rs 8,000.

Addressing all these shortcomings, a group of scientists from Kerala have invented a path-breaking device. Years of research and development culminated in a product that can play a crucial role in detecting breast cancer that too more cheaply.

A team from Thrissur branch of Centre for Materials for Electronics Technology (C-MET) invented a wearable device that is embedded with sensors and incorporates thermal imaging to detect cancerous cells in breasts.

Speaking to the media, a  Dr. sheds light upon the catalytic moment that led the team to developing the innovative “bra” that can detect breast cancer.

“The idea took root when the director of a Cancer Centre visited us sometime in 2014. They’ve been our medical partners in this project. They broached the idea of working out ways of breast cancer detection on a community scale. Mammogram was the golden standard but the provision wasn’t available in even Primary Health Centres across the country. What they had in mind was a portable device that could be implemented at a community level. This propelled us to conceptualise a wearable device for detection through thermal imaging,” she explains.

The next four years went into developing the “bra” and then getting it approved through successful clinical trials conducted at the Cancer Centre.

So, how does this thermal-sensor embedded device work?

“The sensors map the skin temperature of the breasts and detects the presence of any form of abnormalities. Which can then form the basis for patients to take further course of action,” Dr. adds.

She goes on to explain how this device stands out from the regular mammogram, “There is no exposure to radiation with this device as it physically maps the breast skin temperature. In addition to that, the device is portable which makes it perfect for any health care or ASHA worker to carry with them during field visits. It can be easily contained in a small briefcase.”

Another feature is that a person does not experience any pain that is inevitable with the mammogram screening.

“Most importantly, this device ensures the privacy of the wearer because one can wear clothes over it during the test. This is really significant as most women deter from taking the mammogram or any form of clinical screening because of their cultural conditioning and privacy issues,” she elaborates.

Furthermore, the contraption doesn’t have any age restrictions like the mammogram, “Even girls as young as 15 or 20 years of age can use the wearable device which caters to all body types. This is not possible in the case with the mammogram, as only women above 40 can undertake the screening. We have resolved that issue as well,” she adds.

Shedding light on the cost factor, Dr. explains that a digital mammogram machine easily costs about Rs 3.5 crores, while their device with its data acquisition system, amounts up to Rs 25,000 and that is only for one hospital.

A total of 117 patients and 200 volunteers were part of the C-MET team’s clinical trials. Currently, they are working in collaboration with a company to make the technology commercial.

“At present, they are in the training process and as soon as their production begins, another set of clinical trials will be undertaken from their end. As these trials often take some time, we are estimating that the device will be in the market in a year or so,” she informs.

The Dr. specially mentions that this was not an individual project and attributes her team for their years of collective hard work and invaluable contribution that make the innovation a success.

“Receiving awards and recognition is really motivating but what really would validate our years of efforts would be when this device will reach the market and benefit every single woman. That was the sole reason why we immediately put out the device for commercialisation as soon as it fulfilled the clinical trials. We are earnestly waiting for that day,” she concludes.

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Monday, April 23, 2018

A wearable device that is designed to detect abnormalities in breast thermal patterns and tissue elasticity, which can be strong indicators of early stage breast cancer. It consists of two biosensing patches that the user can place on her own brassier. 

The patches collect data that is sent to the user’s phone or tablet through blue-tooth technology, and our Artificial Intelligence algorithms produce a risk assessment within minutes. 

 Thermal Abnormalities
As cancer cells multiply, blood vessels grow around them in a process known as angiogenesis, in order to provide nutrients that allow the tumor to grow. These blood vessel formations are distinguishable from those naturally occurring in the body, and hence breast cancer risk can be assessed by detecting the thermal patterns associated with them.

Tissue Elasticity
Benign and malignant tissues have different elastic properties and hence breast cancer risk can be assessed by quantifying tissue elasticity. Our tactile sensors produce smooth vibrations that excite the breast tissue surrounding the mammary glands, generating elasticity data that our artificial intelligence algorithms study to determine the presence of abnormal masses.

Mode Of Use
The wearable device can be used in the commodity of the user’s home. The user just has to place the device, follow simple instructions on her phone or tablet, and in less than an hour she will have results from her monthly examination. During this time, the user is free to continue with her daily routine as long as she doesn’t engage in intense physical activity and is not heavily exposed to sunlight.

The Oracle Behind The Bra
The device uses state of the art Artificial Intelligence algorithms in order to provide the most reliable results possible with the information collected through its sensors. Our algorithms are in constant refinement, and they learn from each new user they have access to. 

We have fed our algorithms with breast data from about 150 women, and we have obtained a 89% sensitivity (percentage of cancer cases detected as such).

We are confident that our results will only continue to improve as our trials provide more cases for our algorithms to learn from and as our engineers and scientists continue to refine our mathematical models.

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Wednesday, November 01, 2017

Innovative breast cancer early warning system developed

llumina 360, a robot-assisted breast cancer early warning system developed by a city-based medical technology firm, can help in early detection of tumours through thermal imaging and be a boon in tackling the disease that is fast spreading, an official said. 

According to a researcher, the system is the first of its kind in the world in breast cancer detection.

With incidence of breast cancer seen in younger women, Illumina 360 can detect presence of variance in the breasts of women irrespective of their age and without any pain, he said.

According to him, the existing screening systems have negative factors like pain when the breasts get pressed by the machine, women feel shy to be exposed during the screening process, age (only women over 45 can be subject to mammography) and non-ionizing radiation.

However, Illumina 360 eliminates all these handicaps. 

"All that a woman has to do is to lie down on a table just unbuckling her tops and without exposing her breasts. An advanced robot in the scanning chamber will take a 360 degree view of the breast and acquire thermal signature - an early warning signal for breast cancer," he said.

"On seeing an abnormality in the thermal image, the person may be advised some lifestyle changes. After some period similar scan could be taken to check on the status," a Consultant Radiologist said.

According to the researcher, with Illumina 360 mass breast screening from early age can be a reality in poor countries.

He said the equipment will be priced similar to the analog mammography whereas the digital mammography costs around Rs 1 crore.

We at the research institute are here to stimulate, foster and enhance bio-tech innovation that can bridge existing healthcare gaps and improve lives of people. 

"We are pleased to announce the birth of one such innovation -CURA's Illumina 360 degree, to bridge one of the biggest gaps in the country - addressing the biggest killer disease of the country - Breast Cancer. We are proud to have been part of innovating this disruptive innovation." 

One in 28 women get breast cancer and one in two die due to late detection, making survival one of the lowest in the world.


Hope and pray that detection of Breast cancer in its earlier stage is made easy, so many women can survive this dreadful disease in the world.
 

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