Thursday, February 06, 2020

8 Health Benefits of Fasting, Backed by Science

Despite its recent surge in popularity, fasting is a practice that dates back centuries and plays a central role in many cultures and religions.

Defined as the abstinence from all or some foods or drinks for a set period of time, there are many different ways of fasting.

In general, most types of fasts are performed over 24–72 hours.

Intermittent fasting, on the other hand, involves cycling between periods of eating and fasting, ranging from a few hours to a few days at a time.

Fasting has been shown to have many health benefits, from increased weight loss to better brain function.

Here are 8 health benefits of fasting — backed by science.
1. Promotes Blood Sugar Control by Reducing Insulin Resistance
Several studies have found that fasting may improve blood sugar control, which could be especially useful for those at risk of diabetes.

In fact, one study in 10 people with type 2 diabetes showed that short-term intermittent fasting significantly decreased blood sugar levels .

Meanwhile, another review found that both intermittent fasting and alternate-day fasting were as effective as limiting calorie intake at reducing insulin resistance .

Decreasing insulin resistance can increase your body’s sensitivity to insulin, allowing it to transport glucose from your bloodstream to your cells more efficiently.

Coupled with the potential blood sugar-lowering effects of fasting, this could help keep your blood sugar steady, preventing spikes and crashes in your blood sugar levels.

Keep in mind though that some studies have found that fasting may impact blood sugar levels differently for men and women.

For instance, one small, three-week study showed that practicing alternate-day fasting impaired blood sugar control in women but had no effect in men .

    Summary
    Intermittent fasting and alternate-day fasting could help decrease blood sugar levels and reduce insulin resistance but may affect men and women differently.

2. Promotes Better Health by Fighting Inflammation

While acute inflammation is a normal immune process used to help fight off infections, chronic inflammation can have serious consequences for your health.

Research shows that inflammation may be involved in the development of chronic conditions, such as heart disease, cancer and rheumatoid arthritis .

Some studies have found that fasting can help decrease levels of inflammation and help promote better health.

One study in 50 healthy adults showed that intermittent fasting for one month significantly decreased levels of inflammatory markers.

Another small study discovered the same effect when people fasted for 12 hours a day for one month.

What’s more, one animal study found that following a very low-calorie diet to mimic the effects of fasting reduced levels of inflammation and was beneficial in the treatment of multiple sclerosis, a chronic inflammatory condition.

    Summary
    Some studies have found that fasting could decrease several markers of inflammation and may be useful in treating inflammatory conditions, such as multiple sclerosis.

3. May Enhance Heart Health by Improving Blood Pressure, Triglycerides and Cholesterol Levels

Heart disease is considered the leading cause of death around the world, accounting for an estimated 31.5% of deaths globally .

Switching up your diet and lifestyle is one of the most effective ways to reduce your risk of heart disease.

Some research has found that incorporating fasting into your routine may be especially beneficial when it comes to heart health.

One small study revealed that eight weeks of alternate-day fasting reduced levels of “bad” LDL cholesterol and blood triglycerides by 25% and 32% respectively .

Another study in 110 obese adults showed that fasting for three weeks under medical supervision significantly decreased blood pressure, as well as levels of blood triglycerides, total cholesterol and “bad” LDL cholesterol .

In addition, one study in 4,629 people associated fasting with a lower risk of coronary artery disease, as well as a significantly lower risk of diabetes, which is a major risk factor for heart disease .

    Summary
    Fasting has been associated with a lower risk of coronary heart disease and may help lower blood pressure, triglycerides and cholesterol levels.

4. May Boost Brain Function and Prevent Neurodegenerative Disorders

Though research is mostly limited to animal research, several studies have found that fasting could have a powerful effect on brain health.

One study in mice showed that practicing intermittent fasting for 11 months improved both brain function and brain structure .

Other animal studies have reported that fasting could protect brain health and increase the generation of nerve cells to help enhance cognitive function .

Because fasting may also help relieve inflammation, it could also aid in preventing neurodegenerative disorders.

In particular, studies in animals suggest that fasting may protect against and improve outcomes for conditions such as Alzheimer’s disease and Parkinson’s .

However, more studies are needed to evaluate the effects of fasting on brain function in humans.

    Summary
    Animal studies show that fasting could improve brain function, increase nerve cell synthesis and protect against neurodegenerative conditions, such as Alzheimer’s disease and Parkinson’s.

5. Aids Weight Loss by Limiting Calorie Intake and Boosting Metabolism

Many dieters pick up fasting looking for a quick and easy way to drop a few pounds.

Theoretically, abstaining from all or certain foods and beverages should decrease your overall calorie intake, which could lead to increased weight loss over time.

Some research has also found that short-term fasting may boost metabolism by increasing levels of the neurotransmitter norepinephrine, which could enhance weight loss .

In fact, one review showed that whole-day fasting could reduce body weight by up to 9% and significantly decrease body fat over 12–24 weeks.

Another review found that intermittent fasting over 3–12 weeks was as effective in inducing weight loss as continuous calorie restriction and decreased body weight and fat mass by up to 8% and 16% respectively.

In addition, fasting was found to be more effective than calorie restriction at increasing fat loss while simultaneously preserving muscle tissue .

    Summary
    Fasting may increase metabolism and help preserve muscle tissue to reduce body weight and body fat.

6. Increases Growth Hormone Secretion, Which Is Vital for Growth, Metabolism, Weight Loss and Muscle Strength

Human growth hormone (HGH) is a type of protein hormone that is central to many aspects of your health.

In fact, research shows that this key hormone is involved in growth, metabolism, weight loss and muscle strength.

Several studies have found that fasting could naturally increase HGH levels.

One study in 11 healthy adults showed that fasting for 24 hours significantly increased levels of HGH.

Another small study in nine men found that fasting for just two days led to a 5-fold increase in the HGH production rate.

Plus, fasting may help maintain steady blood sugar and insulin levels throughout the day, which may further optimize levels of HGH, as some research has found that sustaining increased levels of insulin may reduce HGH levels.

    Summary
    Studies show that fasting can increase levels of human growth hormone (HGH), an important protein hormone that plays a role in growth, metabolism, weight loss and muscle strength.

7. Could Delay Aging and Extend Longevity
Several animal studies have found promising results on the potential lifespan-extending effects of fasting.

In one study, rats that fasted every other day experienced a delayed rate of aging and lived 83% longer than rats that didn’t fast.

Other animal studies have had similar findings, reporting that fasting could be effective in increasing longevity and survival rates.

However, current research is still limited to animal studies. Further studies are needed to understand how fasting may impact longevity and aging in humans.

    Summary
    Animal studies have found that fasting could delay aging and increase longevity, but human research is still lacking.

8. May Aid in Cancer Prevention and Increase the Effectiveness of Chemotherapy

Animal and test-tube studies indicate that fasting may benefit the treatment and prevention of cancer.

In fact, one rat study found that alternate-day fasting helped block tumor formation.


Similarly, a test-tube study showed that exposing cancer cells to several cycles of fasting was as effective as chemotherapy in delaying tumor growth and increased the effectiveness of chemotherapy drugs on cancer formation .

Unfortunately, most research is limited to the effects of fasting on cancer formation in animals and cells.

Despite these promising findings, additional studies are needed to look at how fasting may influence cancer development and treatment in humans.

    Summary
    Some animal and test-tube studies suggest that fasting could block tumor development and increase the effectiveness of chemotherapy.

How to Start Fasting

There are many different types of fasts, making it easy to find a method that fits your lifestyle.

Here are a few of the most common types of fasting:

    Water fasting: Involves drinking only water for a set amount of time.
 

   Juice fasting: Entails only drinking vegetable or fruit juice for a certain period.
  

  Intermittent fasting: Intake is partially or completely restricted for a few hours up to a few days at a time and a normal diet is resumed on other days.

    Partial fasting: Certain foods or drinks such as processed foods, animal products or caffeine are eliminated from the diet for a set period.


    Calorie restriction: Calories are restricted for a few days every week.

Within these categories are also more specific types of fasts.

For example, intermittent fasting can be broken down into subcategories, such as alternate-day fasting, which involves eating every other day, or time-restricted feeding, which entails limiting intake to just a few hours each day.

To get started, try experimenting with different types of fasting to find what works best for you.

    Summary
    There are many different ways to practice fasting, which makes it easy to find a method that fits into just about any lifestyle. Experiment with different types to find what works best for you.

Safety and Side Effects

Despite the long list of possible health benefits associated with fasting, it may not be right for everyone.

If you suffer from diabetes or low blood sugar, fasting can lead to spikes and crashes in your blood sugar levels, which could be dangerous.

It’s best to talk to your doctor first if you have any underlying health conditions or are planning to fast for more than 24 hours.

Additionally, fasting is not generally recommended without medical supervision for older adults, adolescents or people who are underweight.

If you decide to try fasting, be sure to stay well-hydrated and fill your diet with nutrient-dense foods during your eating periods to maximize the potential health benefits.

Additionally, if fasting for longer periods, try to minimize intense physical activity and get plenty of rest.

    Summary

    When fasting, be sure to stay hydrated, eat nutrient-dense foods and get plenty of rest. It’s best to consult with your doctor before fasting if you have any underlying health conditions or are planning to fast for more than 24 hours.

The Bottom Line

Fasting is a practice that has been associated with a wide array of potential health benefits, including weight loss, as well as improved blood sugar control, heart health, brain function and cancer prevention.

From water fasting to intermittent fasting and calorie restriction, there are many different types of fasting that fit nearly every lifestyle.

When coupled with a nutritious diet and healthy lifestyle, incorporating fasting into your routine could benefit your health.


This is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.     
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Sunday, August 14, 2016

EARLY WARNING SIGNS OF BREAST CANCER

Breast Cancer Breast cancer usually starts as a small, painless lump(s) in the breasts, and later metastasizes into the rest of the body. Diagnosing breast cancer quickly increases the survival rate considerably. Breast cancer is mostly common in women over the age of 50, but it can appear in any woman of any age. It is also possible for men to contract, but these cases are very rare.
Abnormal lumps or swelling of the breasts
The most common symptoms of breast cancer are the appearance of lumps, swelling or edema. They may not be painful, but should be looked at by a doctor nonetheless.

Inflammation, lumps and dimples on the breasts
Visible changes such as inflammation, bumps or dimples on the breasts could be indicative of cancer. Even if you think that the symptoms are barely noticeable, don’t ignore them – if it truly is breast cancer, early discovery can save your life.

Nipples: change in location / inflammation / secretions
If the skin of your nipple changes texture or becomes brittle, if it becomes inflamed, swollen, changes shape or location (flattening or sinking of the nipple), or you experience secretions - these are all common indicators of breast cancer. If the symptoms don’t disappear after a while, consult with your physician.

Other symptoms:

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Tuesday, November 24, 2015

Breast Cancer- early symptoms

Breast cancer usually starts as a small, painless lump(s) in the breasts, and will later metastasize into the rest of the body. Diagnosing breast cancer quickly increases the survival rate considerably. Breast cancer is mostly common in women over the age of 50, but it can appear in any woman of any age. It is also possible for men to contract, but these cases are very rare.
 
Abnormal lumps or swelling of the breasts
The most common symptoms of breast cancer are the appearance of lumps, swellings or endema. They may not be painful, but should be looked at by a doctor nonetheless.
 
Inflammation, lumps and dimples on the breasts
Visible changes such as inflammation, bumps or dimples on the breasts could be indicative of cancer. Even if you think that the symptoms are barely noticeable, don’t ignore them – if it truly is breast cancer, early discovery can save your life.
 
Nipples: change in location / inflammation / secretions
If the skin of your nipple changes texture or becomes brittle, if it becomes inflamed, swollen, its shape changes and its location does as well (flattening or sinking of the nipple), or secretions occur - these are all common indicators of breast cancer. If the symptoms don’t disappear after a while, consult with your physician.
 
Other symptoms:
Chronic pain in the breasts or armpits
Uneven, inflamed blood vessels
Swelling of the armpits or the collar bone
Sores on the breasts 


THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.

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Wednesday, April 02, 2014

Indian scientist develops potential non-insulin diabetes drugs

A young Indian scientist has developed a potential non-insulin drug candidate for diabetic patients that can help eliminate the risk of low-blood glucose shock in case of an insulin overdose.

Arnab De, a PhD in Microbiology and Immunology from Columbia University in New York, has developed the non-insulin drug candidate in collaboration with Richard Di Marchi of Indiana
University.

Patients use insulin to keep their sugar levels in check,an overdose of insulin can lead to low blood-glucose (hypoglycemia), which may cause diabetic-coma and be life-threatening. Insulin treatment has also been reported to cause weight-gain that may exacerbate a diabetic condition, De told PTI.

"We find that there is a peptide hormone in the gut called GLP1 that increases the secretion of insulin only when the blood glucose is high. This effectively eliminates the risk of hypoglycemic shock. Another advantage is that GLP1 administration has been found to stimulate weight-loss.The hormone offers the promise of revolutionizing the
treatment of Type II  diabetes and reduce obesity," he said. 

Regarding the clinical trial of the new drug, De said that GLP-1 has an extremely short half-life of two minutes and this instability has impeded its effective use in patients. As per a study published in the journal Peptide Science, De and Di Marchi "envisioned a prodrug of GLP as a means to extend the duration of action" and their research resulted in several range of options for prolonging peptide action to once-a-day and once-a-week formulations.

"Needless to say, this will be very helpful for patients as we might have a formulation that needs to be taken only once a week as opposed to after every meal" De said. Subho Mozumdar, faculty member ,University of Delhi said that the development of a GLP-1 based pro-drug represents a patient-friendly, diabetic therapeutic. "It is a remarkable breakthrough which might also help to defend against obesity and  perhaps against Alzheimer's disease too. There is a huge market for such a therapeutic in India given the growing number of patients," said Mozumdar.

As per estimates by The International Diabetes Federation, around one in five individuals suffer from some form of obesity.These individuals are three times more prone to heart
attacks or stroke and five times more likely to develop adult-onset of diabetes vis-a-vis individuals without the syndrome.

Indiana University Research and Technology Corporation (IURTC) has applied for patents internationally on these pro-drugs in the world-wide market.De has been conferred the prestigious Young Investigator's Award by American Peptide Society."I hope going forward this drug essentially helps people.That is when the years of hard work and research will pay
off," he added.


ps- this is only for information, always consult you physician before having any particular food/ medication/exercise/other remedies.
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Sunday, March 02, 2014

Gene mutation behind type 2 diabetes identified

Researchers have identified mutations in a gene that can reduce the risk of developing type 2 diabetes, even in people who have risk factors such as obesity and old age.
The current study breaks new ground in type 2 diabetes research and guides future therapeutic development in this disease. In the new study, researchers describe the genetic analysis of 150,000 patients showing that rare mutations in a gene called SLC30A8 reduce risk of type 2 diabetes by 65 percent.
The results were seen in patients from multiple ethnic groups, suggesting that a drug that mimics the effect of these mutations might have broad utility around the globe.
The protein encoded by SLC30A8 had previously been shown to play an important role in the insulin-secreting beta cells of the pancreas, and a common variant in that gene was known to slightly influence the risk of type 2 diabetes.
However, it was previously unclear whether inhibiting or activating the protein would be the best strategy for reducing disease risk - and how large an effect could be expected.
The team set out to ask if the effects of SLC30A8 protective mutations were limited to the two mutations found in populations in Finland and Iceland. As part of the NIH-funded T2D-GENES Project, chaired by Mike Boehnke at the University of Michigan, the Broad Institute had performed sequencing of 13,000 samples drawn from multiple ethnicities.
The T2D-GENES Project joined the collaboration, found ten more mutations in the same gene, and again saw a protective effect. Combining all the results confirmed that inheriting one copy of a defective version of SLC30A8 led to a 65 percent reduction in risk of diabetes.
In laboratory experiments, members of Altshuler's team showed that the protective mutations disrupt the normal function of the protein encoded by SLC30A8, known as ZnT8. The ZnT8 protein transports zinc into insulin-producing beta cells, where zinc plays a key role in the crystallization of insulin. Exactly how the reduction in ZnT8 functions plays a protective role remains unknown.
THE study has been published in the journal Nature Genetics. 

ps- this is only for information, always consult you physician before having any particular food/ medication/exercise/other remedies.
ps- those interested in recipes are free to view my blog-
http://gseasyrecipes.blogspot.com/
for info about knee replacement, you can view my blog-
http://Knee replacement-stick club.blogspot.com/

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