Wednesday, August 27, 2014

Aspirin not only prevents pain but also promotes recovery

According to a new study published online in PNAS, aspirin has a dual role in acting on pain. Not only does it prevent inflammation and pain but also hastens the end of inflammation. 
  According to the study, the drug kills cyclooxygenase, thus preventing production of the prostaglandins that cause inflammation and pain and also prompts the enzyme to generate another compound that hastens the end of inflammation, returning the affected cells to homeostatic health.  Edward A. Dennis said that aspirin causes the cyclooxygenase to make a small amount of a related product called 15-HETE and during infection and inflammation, the 15-HETE can be converted by a second enzyme into lipoxin, which is known to help reverse inflammation and cause its resolution – a good thing.

The researchers found that macrophages contain the biochemical tools to not just initiate inflammation, a natural part of the immune response, but also to promote recovery from inflammation by releasing 15-HETE and converting it into lipoxin as the inflammation progresses. 

Here are some other amazing facts about aspirin you should know:

1. It is the most widely used drug: Aspirin, chemically known as acetylsalicylic acid, is truly a boon to the medical world. This wonder drug was first brought to the pharmaceutical industry in the year 1899, when it was introduced for the treatment of rheumatic fever and gout. Since then it is the most extensively used therapeutic chemical and is still the first choice of treatment for minor pains and fever. 

2. Most people take the drug without even realising it:  Most people don’t realise that they are actually taking an aspirin because it is not only found as a single ingredient but is also present in combination with other prescribed and over-the-counter drugs. Most drugs containing aspirin have it labelled as ASA or spelled out as acetylsalicylic acid.

3. It is used for relieving more than 50 symptoms: The role of aspirin in treatment of various conditions has been studied. Aspirin is most commonly used for symptoms like heartburn, fever, arthritis, stomach ache, sleep disordersmigraine headaches and symptoms of common cold.

4. Aspirin could benefit 11 different cancers: Aspirin has a significant ability to inhibit the growth of cancer cells. A new aspirin drug showed to curb the growth of cancer cells including that of colon, pancreatic, lung, prostate, breast and leukemia. Read (An aspirin a day may keep cancer away!) to know more about the effect of aspirin in cancer treatment. Read more amazing facts about aspirin.

 THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.












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Friday, September 27, 2013

Sore throats may be precursors to heart diseases

Raising community awareness by emphasising that untreated sore throat caused by group A streptococcal (GAS) infection can lead to acute rheumatic fever (ARF) or rheumatic heart disease RHD, is a huge part of the battle.

According to a Dr., the importance of creating awareness of the disease and its sequelae cannot be underestimated, especially in resource-limited conditions.

They said that the importance of these efforts needs to be recognised and barriers to awareness and education understood and overcome while health promotion research for acute rheumatic fever and RHD is prioritised. Maximised case detection within a community dictates that all members of that community are aware of the presentation and diagnosis of the disease, with the highest awareness needed amongst healthcare workers at primary healthcare level.

With increased awareness of the potential effects of sore throat, the authors believed that more families will be encouraged to seek medical help and prevent further cases of ARF or RHD.
"School and educational institutions should be targeted as the most vulnerable population for GAS infections are school-aged children. These have tremendous potential to improve the reach of primary and secondary prevention and case-detection," the authors said.

The authors also advocate for a change in attitudes from healthcare workers who see ARF or RHD as secondary to their plans to treat malaria, HIV, and TB, saying that ARF or RHD treatment can take place alongside treatment for these other life-threatening conditions.
Helping patients understand the treatment with information that is appropriate to their level of comprehension is also vital, using printed material, video, discussion and any other relevant techniques.

ps- this is only for information, always consult you physician before having any particular food/ medication/exercise/other remedies.
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