Thursday, January 23, 2020

Surgical stabilization of rib fractures: Study suggests new interventions

When an arm snaps, a leg cracks or a wrist twists, physicians set the bone to ensure it heals properly and with as little discomfort to the patient as possible. But the same cannot be said for most rib fractures. 

Past practice and teaching call for little to no treatment, even if it takes months for the patient to breathe normally or just get back to work. The prevailing wisdom has been succinct. "Offer medicine for the pain and a ventilator if breathing is an issue," said Evert Eriksson, M.D., a trauma surgeon at the Medical University of South Carolina and co-author of the paper. "But otherwise, the bones will form a callus over time that allows it to function as it needs to." And while that idea has morphed over the last decade to make the multiple-fracture repair more common, patients with less severe fractures often still go untreated despite the pain.


This extended discomfort is what led Denver Health Medical Center surgeon Fredric Pieracci, M.D., along with several other trauma surgeons to conduct a study with members of the Chest Wall Injury Society. Twelve centers from across the United States came together to evaluate the success of surgical stabilization of rib fractures (SSRF), which involves installing a plate to line up the two ends of the fracture and hold them in place throughout the healing process. They theorized that by stabilizing partially displaced and fractured ribs, patients' pain and quality of life would improve.


As recently published in the Journal of Trauma and Acute Care Surgery, patients who underwent SSRF for three or more rib fractures with partial dislocation reported less pain on the numeric pain scale and a better quality of life after their stabilization surgery.


 "This research shows that patients who have partially displaced fractures, as well as some pulmonary compromise, also benefit from a procedure that is usually reserved for a more severely injured cohort," said Eriksson.


Technological limitations have played a role in keeping surgeons from performing this procedure in the past. It wasn't until recently that surgeons acquired the right equipment to keep surgical incisions small and the risk of complications in the pleural space low. By pulling the muscles aside, instead of cutting through them, surgeons are able to access the chest wall and ribs less invasively. Even the material of the stabilization plates has improved, becoming less rigid and moving more naturally with the patient as the chest expands and contracts with each breath, according to Eriksson. 


While the level of narcotic use did not change significantly in patients who received SSRF, these patients consistently reported more comfort and less pain at each interview interval than those who had not undergone the operation. The fractured ribs took just as long to completely heal, but the patients' experiences during this process were far superior, and they reported feeling less pain and easier breathing throughout. 


Patients also experienced fewer complications from their rib fractures. By opening the chest, addressing any additional injuries, guiding the bones back into position and removing any excess blood from the area, surgeons decreased the chances that study participants would have any additional bleeding or fluid accumulation in that space.


 And the difference was statistically significant. Surgeons reported that in the group that underwent SSRF, there was a zero percent pleural space complication rate from their patients' injuries, while the group that did not undergo the procedure experienced a 10% complication rate. 


Next, Eriksson wants to look at other bones that are not treated surgically. "I had a patient from this study come to me and say, 'My chest no longer hurts. You fixed that. But now it's my shoulder that's the problem.' By stabilizing the chest wall, physicians may improve outcomes from clavicle or scapula fractures as well. 


This collaborative multi-center effort presents an opportunity for surgeons to address a different population than is traditionally not considered for operational treatment. "It gives us an opportunity to help a new set of patients," said Eriksson. "And that is important."


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Wednesday, November 21, 2018

Common Prescription Drugs Linked to Increased Dementia Risk

This is a fairly long post, kindly read till the end, where lists of meds which cause memory loss is also mentioned and also other simple diseases which can cause. My next post simple ways to improve memory fog.
We wish it wasn’t the case but, unfortunately, memory loss is a hot topic. People have countless questions about brain diseases such as Alzheimer’s and dementia. What really causes it? Will there ever be a cure? Are there any natural preventatives? How do my other medications that I’m taking affect my risk of such problems?
In fact, many prescriptions have actually been linked to memory loss! We hope to answer these questions and more below. So, if you or a loved one is worried about or currently living with this problem, please keep reading…

How Common Is Alzheimer’s Disease? Most people associate Alzheimer’s with memory loss, one of first and most common symptoms of the disease. On average, the progressive (and currently) irreversible brain disorder starts affecting people after 60 years of age.  However, there are many factors that contribute to an individual’s experience such as their genes, diet, lifestyle habits, and more.
According to Alzheimers.net, there are 44 million people who have Alzheimer’s or a related dementia, approximately 5,700,000 of whom are American. Health officials expect that number to rise to 16 million by 2050. And because it’s the sixth leading cause of death in America – the only one in the top 10 that cannot be cured, prevented, or slowed – it demands everyone’s attention.

10 Early Warning Signs and Symptoms of Alzheimer’s

As outlined by the Alzheimer’s Association, they can include:
  • Memory loss
  • Inability to plan things or solve problems
  • Difficulty completing simple tasks
  • Getting confused about times, dates, and places
  • Inability to understand spatial relationships and visuals
  • New problems when it comes to speaking or writing
  • Forgetting where you put stuff and being unable to retrace steps
  • Increasingly poor judgement
  • Growing less and less social
  • Uncharacteristic changes in mood and personality

How About Dementia?

Not unlike Alzheimer’s disease, the most common form of dementia, general dementia is also a progressive syndrome that impairs your cognitive function. That is, your ability to think, reason, remember, and behave properly (if at all). Many of the symptoms actually overlap with those of Alzheimer’s disease.
Growing by 10 million new cases per year, there are around 50 million people worldwide currently living with dementia… According to the World Health Organization, that’s a figure that we expect to hit 82,000,000 by 2030 and 152,000,000.
Although these numbers are alarming, there are numerous ways to decrease your risk of development Alzheimer’s disease or other forms of dementia – naturally and otherwise. But the possibility of keeping the number of dementia cases to a minimum seems unlikely when so many people are on medications that can increase the likelihood of getting it…

Common Drugs Like Benadryl Linked to Increased Dementia Risk


In March 2015, researchers published a prospective cohort study called “Cumulative Use of Strong Anticholinergics and Incident Dementia.” The researchers conducted the long-term study which tracked 3,434 men and women who were aged 65 and up, and had no dementia when the study began.
The team accessed every participant’s history of drug use for the previous decade, including both over-the-counter and prescription drugs. Over a 7-year timeline, they followed up with all the participants every two years, during which 797 participants developed dementia (637 of whom developed Alzheimer’s disease).
As researchers looked back on what those 797 individuals took, anticholinergic drugs became the main suspect. The most common anticholinergics participants used were tricyclic antidepressants, first-generation antihistamines, and bladder antimuscarinics. Compared to those who didn’t take anticholinergic drugs, people who did for as little as three years were 54% more likely to develop dementia.

What Are Anticholinergics?


Usually, these types of drugs are prescribed to treat problems including urinary incontinence, Parkinson’s disease, and chronic obstructive pulmonary disorder (COPD). Anticholinergic drugs’ main purpose is to block the actions and effects of acetylcholine, a neurotransmitter which causes muscles to contract, activates pain responses and regulates endocrine and REM sleep functions.
It’s just a natural fact of life – as we age, our bodies’ ability to produce acetylcholine decreases. Since the brain actually contains many acetylcholine-producing cells, as a researcher highlights, “blocking its effects can deliver a double whammy to older people.”

If you want to keep your head clear and brain functioning as highly as possible, steering clear of anticholinergic drugs seems ideal. However, it is important to recognize that the long-term study revealed only a small portion of drugs was interfering with cognitive function. So, please discuss with your doctor if you’re thinking of getting off any prescribed medications.

Experiencing Memory Loss? It’s Not Necessarily Alzheimer’s


There are reversible dementias that, although worrisome, people can treat and even overcome. Some of these problems might surprise you:

1) Delirium

Although this condition seems similar to dementia, the mental changes that occur in delirium happen within days in comparison to months or years. Another key distinction between these two problems is that with dementia, you maintain consciousness; with delirium, you don’t.

2) Depression

People with depression have likely experienced moments of forgetfulness and disorientation. A simple way to tell the difference between depression and dementia is looking at the timeline… Depressed people become depressed first and experience memory-related symptoms later, whereas people with dementia become depressed as a result of their declining cognitive function.

3) Vitamin B12 Deficiency

This crucial deficiency can lead to pernicious anemia, a rare condition associated with confusion, slowness, apathy, and irritability. If you suspect this is the case, see your doctor as soon as possible to make sure your body can even absorb vitamin B12 properly.

4) Thyroid Disease

Individuals with hypothyroidism will likely exhibit dementia-like symptoms. One of the best things you can do is get a thyroid hormone blood test to determine the best possible treatment.

5) Alcoholism

People who are alcoholic can suffer bouts of confusion and amnesia which can mimic the same experiences as someone with Alzheimer’s disease. Although alcoholism can deteriorate the ability to remember and orientate oneself, abstinence and overcoming addiction can help reverse dementia.

Think You Have a Memory Problem? This Is What You Should Do


Not all memory problems or moments of forgetfulness mean you have dementia! That alone should let you have a sigh of relief. But, if you or someone you think thinks a seemingly small memory problem is getting worse, there are a few things you can try.
First, make an appointment with your doctor and talk about your experience(s) right away. No matter the hold-ups you might have with doctors, they are our best source and can help point us in the right direction.
Second, get some blood tests done to make sure your dementia-like symptoms aren’t being caused by hormone imbalances or nutritional deficiencies such as vitamin B 12. There might even be some prescription medications that could be causing your cognitive lapses. In that case, simply ask your doctor for more details about the medications you’re taking.
Third, examine your diet and lifestyle habits. This could look like cutting out sugar, eating healthy fats, and getting a bit more daily physical activity. It may be hard to make such habitual changes.
Forth, try incorporating natural supplements into your daily diet. These can include science backed herbal remedies  such as ashwagandha, turmeric, gingko biloba, and/or coconut oil !

Common medications are linked to memory loss! 

The human brain is arguably the most complicated and least understood organ in the human body. It controls everything we do, think, and feel. The size of our human brains is why we have evolved far past any other animal on the planet. We are one of the only mammals on the planet who can remember things from our past, think into the future beyond just where our next meal will come from, and constantly learn new things and discover more about the world around us.
That is what makes dementia so scary. Our memories and ability to learn are what sets apart from all other species on earth. Without it, we can’t function. Dementia takes vibrant, intelligent people and reduces them to a cognitive function of less than most babies.

This is why we need to protect our memory and our brain before we lose it. Unfortunately, in an effort to treat other (mostly man-made) conditions, we have created drugs that solve one problem while slowly stripping us of our memories. It is important to know what these drugs are and how they affect your brain so that you can talk to your doctor about your options and find a solution that doesn’t come with a side of memory loss.

9 Drugs that Cause Memory Loss

1. Antibiotics

Scientists are discovering more and more every day about the importance of the brain-gut connection. .Many hormones and chemicals that affect our brain, such as serotonin, are found primarily in the gut and GI tract. Because of this, antibiotics, which kill off the good bacteria in our intestinal tract along with the bad, have a direct impact on brain function.
Serotonin is an important neurotransmitter in the brain relevant to depression, migraines, and other neurological illnesses.  New research shows that many common antibiotics, especially quinolones, cause extreme confusion, mental delusion, impaired cognitive function and psychiatric disturbance.
Quinolones, especially Fluoroquinolone, have come under the most fire for their effects on the brain. Others include Amoxicillin, Cephalexin (Keflex), and Levofloxacin (Levaquin).

2. Antihistamines


Antihistamines and anticholinergics are found in common over the counter and prescription drugs for allergies, colds, dizziness, and even sleep. They alter brain function by inhibiting acetylcholine, the main neurotransmitter for learning and memory. Decreased acetylcholine is known to cause dementia, memory loss, hallucinations, blurred vision, confusion, and delirium.
These drugs include Benadryl, Vistaryl, Tavist, Clarinex, Oxytrol for Women, and many others.

3. Sleeping Pills

Sleep aids cause memory loss because they dampen brain activity in key parts of the brain, including those responsible for learning and memory. (1) The most prominent of these are the benzodiazepines.
These drugs include Xanax, Valium, Ativan, Librium, Lunesta, Sonata, and Ambien.

4. Statins

Statins are mainly used to help lower cholesterol for those with high levels. The problem is they also lower brain cholesterol levels, which in turn affects its ability to function properly. Memory loss caused by statins is well-known and gives even more incentive to take initiative and lower cholesterol naturally.
Examples of statins include Lipitor, Lescol, Mevacor, Prevachol, Crestor, and Zocor.
If you’re looking for some extra help with your cholesterol levels, why not try Broccoli extract powder? Broccoli Extract is a yellowish powder that is cultivated from the essence of broccoli flowers and stems. Supplementation of broccoli extract is intended to promote overall good cholesterol levels.

5. Antipsychotics

Antipsychotics repress dopamine receptors in the brain, which are responsible for transmitting signals in the brain.(18) These drugs meant to help those who suffer from paranoia, schizophrenia, and bipolar disorder also cause the brain to shrink. This affects brain function as a whole, especially learning and memory, which can lead to dementia, early Alzheimer’s, and other brain-related disorders.
Drugs that fall under this category include Haldol and Mellaril.

6. Antihypertensives

Used to treat hypertension, these beta-blockers interfere with messages in your brain using epinephrine and norepinephrine which affect memory loss, especially your verbal memory.
Antihypertensives are drugs that end in -olol. Common names for these drugs are Tenormin, Coreg, Lopressor, Toprol, Inderal, Betaspace, and Timoptic.

7. Antidepressants and Anti-anxiety


Antidepressants, such as Elavil, Anafranil, Norpramin, and Pamelor, block the action of serotonin and norepinephrine in the brain, which impairs your memory.
Antianxiety drugs, including Xanax, Librium, Klonopin, Valium, and Restoril, dampen activity in the brain related to short and long-term memory.

8. Narcotic Painkillers and Anticonvulsants

Both of these drugs decrease the flow of brain signals to the central nervous system and the emotional reaction to pain. This “slow down” of the brain inhibits its function, including learning and memory.
These drugs include Fentanyl, hydrocodone, morphine, oxycodone, Diamox, Tegretol, Potiga, and Neurontin.

9. Parkinson’s Drugs

These drugs act differently than many of the ones previously mentioned. Parkinson’s drugs activate signaling pathways for dopamine. These pathways function largely for learning and memory, so memory loss which can lead to Alzheimer’s and dementia is a risk.
Parkinson’s drugs include Apokyn, Mirapex, and Requip.

Quick Recap: Medications Linked to Memory Loss

  1. Amoxicillin
  2. Cephalexin (Keflex)
  3. Levofloxacin (Levaquin)
  4. Benadryl
  5. Vistaryl
  6. Tavist
  7. Clarinex
  8. Oxytrol for Women
  9. Xanax
  10. Valium
  11. Ativan
  12. Librium
  13. Lunesta
  14. Sonata
  15. Ambien
  16. Lipitor
  17. Lescol
  18. Mevacor
  19. Prevachol
  20. Crestor
  21. Zocor
  22. Haldol
  23. Mellaril
  24. Tenormin
  25. Coreg
  26. Lopressor
  27. Topro
  28. Inderal
  29. Betaspace
  30. Timoptic
  31. Elavil
  32. Librium
  33. Klonopin
  34. Valium
  35. Restoril
  36. Fentanyl
  37. Hydrocodone
  38. Morphine
  39. Oxycodone
  40. Diamox
  41. Tegretol
  42. Potiga
  43. Neurontin
  44. Apokyn
  45. Mirapex
  46. Requip

Next Steps

The drugs listed above are just a few of the hundreds that fall into these categories. It is important that you know what you are taking and what the potential side effects are. If you are taking one of the over-the-counter options above and it is for occasional use, try to find an alternative. However, if you are currently a drug that is for a chronic illness and prescribed by a doctor, do not go off of the drug. Please talk to your doctor first about your concerns so that you can find an alternative solution.

ps- see my next post for natural remedies for these problems.

 THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.                                                                                                                                                                                                                                                                                        PS- THOSE INTERESTED IN RECIPES ARE FREE TO  VIEW MY BLOG-                                                                                           https://gseasyrecipes.blogspot.com/                                                                                                                                                                             FOR INFO ABOUT KNEE REPLACEMENT, YOU CAN VIEW MY BLOG-                                                                                                                             https:// kneereplacement-stickclub.blogspot.com/                                                                                       FOR CROCHET DESIGNS                                                                                                                                                                                                                                 https://gscrochetdesigns.blogspot.com   

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Saturday, March 01, 2014

New painkiller pill set to kill people as soon as it hits shelves!

A new FDA-approved painkiller isn't set to hit pharmacy shelves until next month, but critics are already warning that popping just two pills could be lethal.
Zohydro, which the FDA gave the green light in October against the advice of its advisory panel, will serve as a powerful pain pill for those who can't get relief from what's already out there.
It contains the same basic ingredient (hydrocodone) as Vicodin, but it has 5 to 10 times the power, Forbes noted, and without the added acetaminophen.
As an expert on the advisory board who voted "no" told NBC News, that acetaminophen deters savvy addicts from loading up on Vicodin for fear of liver damage.
Like OxyContin, Zohydro is a "pure narcotic"; but unlike OxyContin, the Zohydro set to be released isn't tamper resistant, and can easily be crushed, then snorted or injected. 

ps- this is only for information, always consult you physician before having any particular food/ medication/exercise/other remedies.
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