Wednesday, December 13, 2017

Nutritional benefits of Capsicum / Bell peppers

Capsicum is known by a variety of names such as Bell Peppers, Paprika, Cayenne, and Chilies. They come in various colours like green, red and yellow. It is an excellent source of Vitamin A, Vitamin C, beta-carotene and other carotenoids, such as lutein, beta-cryptoxanthin, and zeaxanthin.

1.Burns more Calories:
Red bell peppers help in activating thermogenesis and increase the metabolic rate. Capsaicin which is responsible for increasing the hotness of other peppers is found in bell peppers in very small amounts. Thus, they have a mild thermogenic action that increases the metabolism without increasing the heart rate and blood pressure unlike hot peppers. Hence, they can support weight loss.

2. Good For Eye-sight-
 Vitamin A which is necessary for healthy vision is present in abundance in capsicum. The role of vitamin A in strengthening the immune system along with its antioxidant properties makes capsicum a must included food in your diet.

3. Good for Heart Health-
Red bell peppers are rich in lycopene, thus making them excellent for a healthy heart whereas green bell peppers are a good source of cholesterol lowering fiber. Increased homocysteine levels can lead to a higher risk of heart disease. Bell peppers contain vitamin B6 and folate which help to lower homocysteine levels. In addition to these, the powerful antioxidants vitamins A and C present in these vegetables help to wipe out free radicals. Potassium contained in bell peppers lowers about 162 milligrams of blood pressure which is also beneficial for heart.

4. Anti-cancer-
 Being rich in antioxidant and anti-inflammatory nutrients, bell pepper provides several anti-cancer benefits. The risk of cancer increases due to chronic excessive inflammation and chronic unwanted oxidative stress. These factors can be offset with regular intake of phytonutrients having antioxidant and anti-inflammatory properties. Moreover, bell peppers also contain health supportive sulphur compounds. The enzymes in bell pepper help to prevent gastric cancer and esophageal cancer. The carotenoid lycopene is found to be effective in the prevention of prostate, bladder, cervix and pancreas cancer.The compound lycopene present in capsicum has anticarcinogenic properties and is especially helpful in preventing the incidence of prostate cancer. Capsicum is also a rich source of Vitamin C which goes a long way in the prevention of cancer.

5.Aids Immune System-
Vitamin C is vital for maintaining a healthy immune system and for building strong collagen to support skin and joints. It is instrumental in lowering the risk of arthritis and reducing inflammation. Vitamin K aids in the formation of blood clots. It is important for developing strong bones and protection of cells from oxidative damage.Capsicum (especially the red and yellow capsicum) contains ascorbic acid and antioxidants in abundance. As a result, capsicum comes across as a powerful immune boosting food that keeps various microbial infections, including flu and common cold at bay. The wonder food comes as a great relief for asthmatic patients.

6. Rich In Folate-
The red and yellow capsicum is an excellent source of folate. Folate is an important nutrient that contributes towards the development of the fetal brain and is thus highly recommended for pregnant women. The daily intake of dietary folate lowers the risk of birth defects such as spina bifida.

7.Benefits of Capsaicin:   

Capsaicin is found in the white membranes of peppers which is responsible for imparting heat to the seeds as well. It lowers the cholesterol levels and triglycerides. It kills the ulcer causing bacteria in the stomach and boosts immunity.

8. Benefits of Potassium:

Bell peppers are good sources of potassium. This mineral helps in keeping the fluids and minerals balanced in the body. It enhances muscle function and regulates blood pressure.

9.Cures Iron Deficiency:
Red bell peppers provide almost 300 percent of the daily vitamin C requirement. Vitamin C is essential for the proper absorption of iron. Thus, those suffering from iron deficiency should consume red peppers.

 10.Detoxifying Properties:
Bell peppers help in clearing out the congested mucus membranes in the nose and lungs and eliminate toxins through sweating.

11. Gastrointestinal problems-
Bell pepper juice has proven to be effective in curing gastrointestinal disorders such as ulcers, diarrhea and dyspepsia. It also lowers the incidence of several respiratory problems such as emphysema, asthma and infections in the lungs. Drinking bell pepper juice is an effective remedy against sore throats and nose bleeds.

12. Healthy hair and nails-
 Green bell pepper has a high content of natural silicon, which may support healthy hair and nails.

13.Enhances Hair Growth & Health:
Applying bell pepper on hair can be effective in triggering hair growth through the improvement of blood circulation in the scalp. Boil a few dry red bell peppers in water and leave it for 5 to 6 minutes. After cooling it, massage it on your scalp with the help of a cotton pad and leave it for 10 to 15 minutes. Then wash off the hair. This should be done twice a week for best results. The spiciness of bell pepper enhances the growth and health of the hair.

14.Strengthens Hair Follicles:
One of the reasons why bell peppers plants and the fruits are good for hair is the fact that they are excellent sources of vitamin C which is essential for hair health. Vitamin C helps in proper absorption of iron, thus ensuring that there is enough iron in red blood cells to carry oxygen to hair follicles. Vitamin C is also used in the formation of collagen. Collagen is required by hair follicles, blood vessel and skin to stay healthy and for their optimal growth. Vitamin C deficiency can cause dry, splitting hair that breaks easily.

15.Fights Oxidative Damage:
Red, green and yellow bell peppers are rich in vitamin C which helps in the production of collagen. Collagen keeps the skin firm and protects the cells from further damage. It increases the ability of the skin to fight against oxidative damage.

16.Heals Shingles & Athlete’s Foot:
Due to their anti-fungal and anti-bacterial properties, bell peppers can alleviate infections like shingles and athlete’s foot in combination with proper medication.

17.Reverses Signs of Ageing:

Consumption of bell pepper juice helps in reversing the signs of ageing due to its high antioxidant levels. Bell peppers protect the skin from damage-causing free radicals, thus promoting healthy and younger looking skin.

18. Clears Skin Blemishes & Rashes:

A mixture of carrot and green bell pepper juice can be very effective in clearing blemishes and rashes on the skin.

THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.   

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Saturday, December 31, 2016

New targets found for treating bone marrow disorders


Scientists have found a new mechanism that controls blood cell function and several possible molecular targets for treating a group of pre-malignant disorders in which bone marrow does not produce enough healthy blood cells.

Myelodysplasia syndromes (MDS) can lead to acute myeloid leukaemia (AML), a fast-spreading blood cancer that can be deadly if not treated promptly.


Researchers from Cincinnati Children's Hospital Medical Centre in the US led by cancer biologist Daniel Starczynowski, found that overexpression of a protein called TRAF6 in hematopoietic (blood) cells drives the onset of MDS.

TRAF6 normally functions as an immune sensor of pathogens, researchers said.

"We found that TRAF6 over-expression in mouse hematopoietic stem cells results in impaired blood cell formation and bone marrow failure," said Starczynowski, from the Cincinnati Children's Hospital Medical Centre.

"Based on our paper, a number of therapeutic approaches can be tested and directed against TRAF6 and other related proteins responsible for MDS," said Starczynowski.

In testing on laboratory mouse models and human MDS/AML samples, the researchers identified a novel substrate of TRAF6 called hnRNPA1, an RNA binding protein.

They also found molecular interactions with Cdc42, a protein that helps regulate cells also implicated in cancer.

All of these could be potential treatment targets for cases of MDS triggered by over-expression of TRAF6, according to Starczynowski, who said future studies will test their therapeutic potential in mouse models of MDS.

The researchers were able to identify the new molecular targets by conducting a global proteomic analysis of human leukemia cells.

This allowed them to the see entire complement of proteins regulated by TRAF6 in leukemia cells.

Beyond the potential for new therapeutic approaches in treating MDS or AML, the research showed a new and critical immune-related function for TRAF6, scientists said.

In response to various pathogens, the protein also regulates RNA isoform expression, an important step in the translation of genetic code into protein and cell formation.

In the context of the current study, TRAF6's regulation of RNA isoform expression is important to the function of hematopoietic cells and reveals another dimension to how cells respond to infection, Starczynkowski said.

The research was published in the journal Nature Immunology.


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