Dim Light Escalates Breast Cancer's Spread to Bones

Exposure to dim light at night may contribute to the spreading of breast cancer to bones, researchers have shown in an animal study.
When breast cancer spreads it often affects bones, cause severe pain and make them fragile. "To date no one has reported that exposure to dim light at night induces circadian disruption, which increases spread of bone metastatic breast cancer," said an Assistant Professor.
  
For the preliminary study, the team created a mouse model of bone metastatic breast cancer. They injected oestrogen receptor-positive human breast cancer cells, which have a low propensity to grow in bones, into the tibia (shinbone) of female mice.

Like humans, mice produced a strong night-time circadian melatonin signal, shown to produce strong anti-cancer actions and for promoting sleep.

While one group of mice was kept in the light for 12 hours each day, the other group of three mice in the dark for 12 hours. Another group spent 12 hours in light, followed by 12 hours in dim light at night.

X-ray images showed that mice exposed to a light or dim light cycle had much larger tumours and increased bone damage compared with mice kept in a standard light/dark cycle, he noted.

"Our research identified the importance of an intact nocturnal circadian melatonin anti-cancer signal in suppressing bone-metastatic breast tumour growth," said the Asst. Prof.

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VARIOUS HEALTH BENEFITS OF VITAMIN C

We all know that Vitamin C is water-soluble vitamin. So, we need to consume it daily.t plays a vital role in heart, eyes, skin, and prenatal health and immunity. Long-term non-availability of vitamin C can lead to various symptoms, which though are not immediately threatening, can turn dangerous in the long run.

 Skin bruises: Easy bruising is one of the early symptoms of vitamin C deficiency. There could be capillaries which appear superficial and have an increased tendency to bruise and bleed. There could also be unexplained reddish purple marks on the skin in people who have low levels of vitamin C.

 Bleeding gums: Another major indicator of vitamin C deficiency is swollen gums that tend to bleed easily. This again is related to their role in collagen formation and if not identified and treated in the early phases, it can lead to severe gum infection, periodontal disease, and even loss of teeth.

 Slow healing: Vitamin C has an important role to play in connective tissue formation, and if there is less of vitamin C in the body, collagen formation is delayed. This can lead to prolonged and delayed healing of wounds, even simple ones like cuts and bruises. The added role of vitamin C as an immune booster also leads to reduced healing when there is vitamin C deficiency.
 
 Nosebleeds: Frequent unexplained nosebleeds is another sign of vitamin C deficiency. Reduced amounts of vitamin C make the capillaries fragile causing them to bleed easily.

Dry skin: While weather does determine if the skin is dry or normal, vitamin C also does. The decreased levels of collagen can lead to an unhealthy skin which can turn red and can be dry and can also lead to keratosis pilaris, which is an accumulation of melanin pigments in the skin. Good amounts of vitamin D helps as a good anti-ageing agent and reduces wrinkles and retains moisture. It also has sun protective effects and antioxidant properties.

Unexplained weight gain: Vitamin C plays a vital role in fat metabolism and therefore deficiency leads to weight accumulation, especially around the waist. It helps oxidise fat and so helps in weight regulation.
 
Low immunity: Vitamin C deficiency affects the body’s susceptibility to infections, making it prone to more severe and frequent infections. People catching a common cold very frequently could be suffering from vitamin C deficiency.

Emotional health: Vitamin C is also a mood regulator, so inadequate amount can lead to depression. Try eating a juicy orange to start feeling better.
    
 this is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.
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