Health coach shares 5 longevity hacks to support long-term brain health and lower the risk of Alzheimer's disease

Simple daily habits can not only improve your present brain health, but can add up over the years and lower cognitive decline in old age. 

Alzheimer’s disease and dementia don’t suddenly appear in old age - they are often the result of decades of small, everyday habits quietly adding up over time. The choices you make today around food, sleep, movement and inflammation can shape how well your brain functions years from now. By prioritising brain health early, you’re not just improving how you think and feel in the present - you’re investing in a sharper, healthier future that your 80-year-old self may one day thank you for.

Alejandra Ruff, an integrative nutrition health coach specialising in women’s longevity, chronic disease prevention and brain health, has shared five science-backed longevity strategies designed to support cognitive function and reduce the risk of Alzheimer's disease.

In an Instagram video shared on December 15, the health coach explains, “Dementia doesn’t begin when you’re old. It begins decades before you ever feel a symptom. And while that sounds terrifying…it’s actually the most empowering truth you’ll hear today: Your brain’s future isn’t fixed. You can change your trajectory - starting right now.”

Prioritise omega-3s

Alejandra advises prioritising omega-3 rich foods - such as fatty fish like sardines and salmon, along with nuts and seeds like chia, flaxseeds and walnuts - almost as if it were your job, noting that they play a key role in supporting brain health and calming inflammation.

She explains, “Your brain is 60 percent fat, and omega-3s are the raw materials it needs to repair, protect, and stay sharp. EPA and DHA literally build your brain cells and calm inflammation - two things that matter for dementia risk.”

Treat sleep like brain-washing

According to the health coach, sleep acts like a deep cleansing cycle for the brain, clearing out metabolic waste - including proteins linked to Alzheimer’s disease - that accumulate during the day and are flushed out while you sleep.

She explains, “While you sleep, your brain flushes out waste - including the proteins linked to Alzheimer’s. If you skip sleep, that waste doesn’t get cleared. Your nighttime routine is not a luxury. It’s a neuroprotective strategy.”

Avoid spiking blood sugar frequently

Alejandra warns against repeatedly spiking blood sugar throughout the day, noting that frequent glucose highs and crashes can accelerate brain ageing and impair long-term cognitive health. She highlights, “Glucose spikes equals inflammation, energy crashes, mood swings, and faster brain ageing. Balanced blood sugar keeps your mind clear and your neurons happy.”

The health coach recommends always prioritising proteins and fibres, along with some form of movement after meals to balance out glucose spikes.

Move every 2-3 hours

According to Alejandra, regular movement is essential for brain health and shouldn’t be limited to a single 30-minute workout. She emphasises the importance of moving your body every two to three hours throughout the day to support overall brain wellbeing.

She explains, “Movement increases blood flow to your brain right away. Strength training boosts BDNF - aka ‘Miracle-Gro’ for your brain.”

Eat to lower inflammation

According to the health coach, inflammation acts as a silent accelerant of cognitive decline, and prioritising targeted, anti-inflammatory nutrition on a daily basis can support brain health and potentially lower the risk of Alzheimer’s disease.

She recommends, “Whole, colourful foods protect your neurons, your mitochondria, and your long-term memory. More greens, berries, olive oil, fish, herbs, turmeric, veggies. Less processed chaos.”

 

 

This is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.   

https://gscrochetdesigns.blogspot.com. one can see my crochet creations  

https://gseasyrecipes.blogspot.com. feel free to view for easy, simple and healthy recipes    

https://kneereplacement-stickclub.blogspot.com. for info on knee replacement

https://GSiyers home remedies.blogspot.com   is the latest addition to my blogs

 

 

Multiple sclerosis: Skin cells may help to repair nerve damage

A personalized treatment for multiple sclerosis may be one step closer, thanks to a new study that reveals how a person's own skin cells could be used to repair the nerve damage that the disease causes.

Led by scientists in the United Kingdom, the study took skin cells from adult mice with multiple sclerosis (MS) and then reprogramed them into neural stem cells (NSCs).

These "induced neural stem cells" (iNSCs) were transplanted into the rodents' cerebrospinal fluid.

There, they reduced inflammation and repaired damage to the central nervous system (CNS).

Lead study author and his team believe that their strategy could offer a promising treatment for MS and other neurological diseases.

MS is a progressive neurological disease that is estimated to affect more than 2.3 million people across the globe.

While the precise causes of MS remain unclear, "an abnormal immune system response" is thought to be involved. Such a response leads to inflammation in the CNS, which causes the destruction of myelin, or the fatty substance that protects nerve fibers.

As a result, the nerve fibers become damaged. This disrupts neuronal signaling and triggers the neurological symptoms of MS, including tingling in the face or extremities and problems with movement, balance, and coordination.

Using stem cells to treat MS
Previous research has investigated the use of NSCs for the treatment of MS. NSCs are stem cells that have the ability to transform into different types of cell in the CNS — including neurons and glial cells.

However, there are some barriers to this strategy. As researchers note, NSCs are derived from embryos, and it would be hard to obtain them in high enough quantities to sustain clinical treatment.
It is also possible that the immune system would see embryo-derived NSCs as foreign invaders and try to destroy them.

As such, researchers have turned their attention toward iNSCs, or NSCs that can be developed by reprogramming adult skin cells. Importantly, since these cells would be derived from the patients themselves, the risk of an immune system attack would be significantly reduced.

To test whether iNSCs could be a feasible treatment option for MS, the researchers tested them on adult mice that had been genetically engineered to develop the condition.

The team took cells from the skin of the mice and reprogramed them into NSCs, effectively making iNSCs. Next, the team transplanted these iNSCs into the cerebrospinal fluid of the mice.
Study yields promising findings

The researchers found that this led to a reduction in levels of succinate, which is a metabolite that the team found is increased in MS. This increase prompts microglia — a type of glial cell found in the CNS — to trigger inflammation and cause nerve damage.

By reducing succinate levels, the iNSCs reprogrammed the microglia — which, in turn, reduced inflammation and brain and spinal cord damage in the mice.

Of course, human clinical trials are needed before iNSCs can be considered as a suitable treatment for MS, but this latest study certainly shows promise.

"Our mouse study suggests that using a patient's reprogrammed cells could provide a route to personalized treatment of chronic inflammatory diseases, including progressive forms of MS."   said the lead author.

"This is particularly promising," Dr.  adds, "as these cells should be more readily obtainable than conventional neural stem cells and would not carry the risk of an adverse immune response."

this is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.   
https://gscrochetdesigns.blogspot.com. one can see my crochet creations  
https://gseasyrecipes.blogspot.com. feel free to view for easy, simple and healthy recipes    
https://kneereplacement-stickclub.blogspot.com. for info on knee replacement     
 

Novel app may predict hernia risk after abdominal surgery

Researchers have created an app that may predict the likelihood of developing an incisional hernia following an abdominal surgery, using Big Data analytics to potentially help address a problem effects one out of every 8 of these surgical patients.

The team developed the app utilising electronic health records (EHR) to identify the most common risk factors for patients, as well as which surgeries most commonly result in incisional hernias across multiple specialties.

Our tool presents the risk for each case at the point of care, giving surgeons and patients the chance to consider this outcome ahead of time and incorporate data into the decision-making process, said the co-author of the study.

Incisional hernias occur after abdominal surgery at the site of the surgical wound when the contents of the abdomen can push through the muscle.

For the study, the team analysed the EHRs of 29,730 patients undergoing intra-abdominal urological or gynecological surgery between Jan. 2005 and June 2016.

They found more than 1,100 of these patients ended up requiring a second surgery following the primary operation to repair the incision hernias.

Colorectal surgeries were the most common specialty associated with incision hernias, followed by vascular, bariatric and transplant.

The analysis also identified risk factors that made a patient more likely to develop an incisional hernia.

The most common was a history of abdominal surgery, which increased the likelihood in 87.5% of cases. That was followed by a history of smoking and a recent infection 75 % for both. Obesity was also a significant risk, though it was weighted less than other risk factors.

 

THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.                                    PS- THOSE INTERESTED IN RECIPES ARE FREE TO  VIEW MY BLOG-                                                                                           https://gseasyrecipes.blogspot.com/    

                                                                                                                                                     FOR INFO ABOUT KNEE REPLACEMENT, YOU CAN VIEW MY BLOG-                                                  https:// kneereplacement-stickclub.blogspot.com/  

         

                   FOR CROCHET DESIGNS                                                                                                                                                                                                  https://gscrochetdesigns.blogspot.com 

Researchers have created an app that may predict the likelihood of developing an incisional hernia following an abdominal surgery, using Big Data analytics to potentially help address a problem effects one out of every eight of these surgical patients. The team developed the app utilising electronic health records (EHR) to identify the most common risk factors for patients, as well as which surgeries most commonly result in incisional hernias across multiple specialties.

https://www.thehansindia.com/tech/novel-app-may-predict-hernia-risk-after-abdominal-surgery-520910

Researchers have created an app that may predict the likelihood of developing an incisional hernia following an abdominal surgery, using Big Data analytics to potentially help address a problem effects one out of every eight of these surgical patients. The team developed the app utilising electronic health records (EHR) to identify the most common risk factors for patients, as well as which surgeries most commonly result in incisional hernias across multiple specialties.

https://www.thehansindia.com/tech/novel-app-may-predict-hernia-risk-after-abdominal-surgery-520910

New Drug Combo Could Repair the Brains of Alzheimer’s Patients

Neurons receive, process, and transmit all the impulses in our brains. Essentially, they’re the building blocks of the human nervous system, and once they’re damaged by Alzheimer’s disease or some other brain injury, they’re done for — they have no regenerative abilities.

In contrast, the glial cells that support and insulate neurons do have regenerative abilities, and now, researchers think they've found an efficient way to actually transform glial cells into neurons — a discovery that could lead to a pill to repair brain damage.

Molecular Report

Based on a previous study, the team knew it was possible to convert human glial cells into neurons using a sequence of nine tiny molecules. However, the large number of molecules and specific sequence made transitioning the research from the lab to something that could work in a clinical environment difficult.

In a study published on Thursday, the  team describes how it found a way to streamline the process of creating neurons out of a type of glial cells called astrocytes with remarkable success.

“We identified the most efficient chemical formula among the hundreds of drug combinations that we tested,” a researcher said in a press release. “By using four molecules that modulate four critical signaling pathways in human astrocytes, we can efficiently turn human astrocytes — as many as 70 percent — into functional neurons.”

Dream Delivery

 The team acknowledged in the press release that it still has a long road ahead before its latest research will be able to help people with brain damage, but it’s extremely optimistic about the future.
“The most significant advantage of the new approach is that a pill containing small molecules could be distributed widely in the world, even reaching rural areas without advanced hospital systems,” research leader said.

“My ultimate dream is to develop a simple drug delivery system, like a pill, that can help stroke and Alzheimer's patients around the world to regenerate new neurons and restore their lost learning and memory capabilities,” he continued. “Our years of effort in discovering this simplified drug formula take us one step closer to reaching our dream.”

 

THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.                                    PS- THOSE INTERESTED IN RECIPES ARE FREE TO  VIEW MY BLOG-                                                                                           https://gseasyrecipes.blogspot.com/       

                                                                                                                                                                    FOR INFO ABOUT KNEE REPLACEMENT, YOU CAN VIEW MY BLOG-                                                  https:// kneereplacement-stickclub.blogspot.com/           
                                                                           FOR CROCHET DESIGNS                                                                                                                                                                                                  https://gscrochetdesigns.blogspot.com

Breathing Pure Oxygen Could Repair Brain Damage Years After a Concussion

Researchers have revisited hyperbaric oxygen sessions as a possible treatment for brain damage sustained after a concussion. According to a report compiled for experts, in a single year, approximately 2.2 million emergency room visits were for traumatic brain injuries (TBI). The majority of these injuries are considered mild and are commonly called concussions. These injuries are common in contact sports and in soldiers.

Most individuals who suffer a concussion are able to heal back to normal brain activity, yet up to five percent of sufferers can experience long-term symptoms. This is called post-concussion syndrome and it can manifest with headaches, mood changes, and other cognitive problems. The symptoms are caused by damage to blood vessels in the brain, making it more difficult for the organ to receive adequate oxygen.

A study published in 2013 showed that treating post-concussion syndrome patients with pure oxygen significantly improved cognitive function and quality of life for participants. Research  shows exactly how this treatment heals the brain. The lead researcher explained that “Once the extra oxygen diffuses into damaged areas, it supplies energy and the regenerative process can happen.” The extra oxygen helped to regrow blood vessels and nerve fibers.

This treatment was previously tested in 2015 by researchers. They concluded that the treatment was not effective. However, their conclusions were based on a faulty interpretation of their supposed “sham” treatment. The researchers subjected a group of participants to a pressurized chamber with normal levels of oxygen. These patients also showed improved cognitive function, so the researchers concluded that the treatment was no more effective than breathing normally.

However, the researchers did not account for the higher pressure actually allowing more oxygen to enter the brain, thus performing along the same lines as the patients who were actually receiving the active treatment. “It was meant to be a sham treatment, but it was actually an active treatment,” says the researcher.

Using hyperbaric oxygen treatments for post-concussion syndrome still needs to be approved by the FDA. More research is needed to confirm its safety and efficacy. However, should the treatment prevail, it will be the first to tackle the underlying causes of the syndrome, as opposed to treating individual symptoms.

THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.                                    PS- THOSE INTERESTED IN RECIPES ARE FREE TO  VIEW MY BLOG-                                                                                           https://gseasyrecipes.blogspot.com/       
                                                                                                                                                                      FOR INFO ABOUT KNEE REPLACEMENT, YOU CAN VIEW MY BLOG-                                                  https:// kneereplacement-stickclub.blogspot.com/           
                                                                           FOR CROCHET DESIGNS                                                                                                                                                                                                  https://gscrochetdesigns.blogspot.com