How to be positive in times of crisis like now

I know that most people are worried about the dreaded corona-virus - COVID-19, that has become pandemic now. Most countries have put a ban on people entering their countries, even its own citizens from the virus affected countries. Some may call it unwanted action by the government. NO. The main reason for the virus becoming pandemic is easy travel of people from affected places to other places within their own country or other countries. 

Just like what happens, when one child has chickenpox at home, then the other child will surely get it after 15 days, even if you got the children separated once the pox was seen. Actually, when fever starts itself, one is in contagious state, but no one knows that. So, you can't blame anyone. As for corona-virus, some people who are healthy, may not show any sign or usual symptoms associated with the disease. Luckily, due to their strong immune system, they're able to fight it. But, when they go near those whose immune systems are poor, they can spread the disease. 

What is most important is precaution. 
1) stay away from crowded places
2) wear mask in case you do have to go out
3) when outside, where you may touch, but DON'T touch your face, nose or eyes till you've washed your hands well with soap.
4) When you sneeze or cough, cover your mouth well, so that you don't spread the germs to others.
5) don't think isolation is bad, it is necessary to curtail the spread of the disease and for one's own safety.
6) don't panic if you've fever or cold, as not all all cold and fever are due to corona-virus. In case, you don't get relief from taking medicine for normal flu, contact your physician to rule out other infections.
7) this is the time for meditation, yoga, introspect, have positive thoughts and eat healthy, be happy.
8) When you're positive, your good hormone levels increase, which boosts your immunity.
9) listen to music, though in isolation, thanks to technology, you can still stay connected with your near and dear ones through Whatasapp calls, video calls, then you can see your loved ones, which will make you happy.

Good luck to all, self-curtailment is the need of the hour now. It is for your own good and for the good of others too. Be happy. 

Don't panic, according to predictions, by the end of this month, the virus will slowly fade away and by mid next month, everything will be back to normal.

This is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.     

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New immune cell with 'Jekyll and Hyde properties' identified

Scientists at Trinity College Dublin have identified a rare, new cell in the immune system with "Jekyll and Hyde properties". These cells play a key protective role in immunity to infection but - if unregulated - also mediate tissue damage in autoimmune disorders.

The findings should help us design more effective vaccines to prevent infections such as MRSA, and may also assist help us develop of new therapies for autoimmune diseases, such as multiple sclerosis or rheumatoid arthritis.

The immune system functions to control infection, utilizing various immune cells, such as T cells to respond to and control invading microbes. However, if these immune cells are not highly regulated, they can attack and damage body tissues, leading to the development of autoimmune diseases.

Molecules called T cell receptors (TCRs) allow T cells to recognize components of infectious agents with exquisite specificity. The TCRs enable T cells to respond to and eventually eliminate the infectious agent.

Professor Kingston Mills said:   Until now scientists thought that there were two discrete populations of T cells, expressing either 'αβ' or 'γδ' TCRs. The αβs are the most common T cells in the body. They play a key role in remembering prior infection or immunization and thereby help protect us against re-infection and mediate vaccine-induced protective immunity. The γδs are more prevalent at mucosal surfaces, such as the lung or gut, and provide an immediate first line of defense against pathogens that invade through these routes."

We have discovered a new cell type that expresses both αβ and γδ TCRs. This rare population of chimeric or hybrid αβ-γδ T cells has properties of both αβ and γδ T cells. Importantly, they are normally highly activated and poised to act as first responders to control bacterial infection. However, given this high level of activation, they are effectively 'Jekyll and Hyde cells' because in certain contexts they can also precipitate autoimmune responses."

Using a model of Staphylococcus aureus infection, Professor Mills and his team found that these cells are rapidly mobilized during infection and play a key role in quickly eliminating the microbes from the body.

The induction of these hybrid αβ-γδ T cells may thus represent a novel approach in the design of more effective vaccines against Staph aureus and other infectious diseases, while advancing our ability to control their response may yield additional therapeutic options.

Professor Mills added:   In a model of autoimmune disease, we found that the hybrid T cells can also trigger the inflammatory cascade that mediates tissue damage in autoimmunity. Therefore, approaches for inhibiting these highly activated immune cells in susceptible individuals may open up new approaches for the treatment of autoimmune diseases such as psoriasis and multiple sclerosis."

This is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.     

https://gscrochetdesigns.blogspot.com. one can see my crochet creations  
https://gseasyrecipes.blogspot.com. feel free to view for easy, simple and healthy recipes    
https://kneereplacement-stickclub.blogspot.com. for info on knee replacement