Monday, July 07, 2025

This Japanese walking technique improves health and prevents disease

People often clock thousands of steps a day yet still wonder why the scale or their blood pressure hardly budges. A simple twist on walking, first tested in Japan, may be the missing ingredient.

This “Japanese walking” exercise methodology, called interval walking training (IWT), swaps steady strolling for bursts of brisk movement, then recovery‑paced steps.

Cardiometabolic researcher Kristian Karstoft of the University of Copenhagen’s Center for Healthy Aging has spent more than a decade tracking its effects.

Why pace changes matter

Most walkers cruise at one comfortable speed and never raise their heart rate high enough to stimulate deeper adaptations.

Switching between fast and slow bouts nudges the body to use oxygen more efficiently, a trait measured by VO2peak.

That oxygen boost drives down resting blood pressure and encourages muscles to burn more sugar for fuel. It also keeps a session feeling manageable because the recovery intervals prevent the distress that can accompany continuous hard effort.

Regular shifts in speed even appear to sharpen insulin action, regulating blood sugar swings that set the stage for diabetes.

Scientists call that improvement better glycemic control, a term describing how tightly the body keeps glucose within a healthy range.

How “Japanese walking” works

Japanese physiologists outline a straightforward walking recipe, alternating three minutes at roughly seventy percent of personal maximum effort with three minutes around forty percent. Completing five of these cycles takes about half an hour.

“Additionally, interval walking training is a great way to meet the recommended 150 minutes a week of moderate‑intensity aerobic activity,” noted the sports medicine specialist.

That schedule, performed on at least five days each week, fits neatly into current public‑health advice to accumulate one hundred fifty minutes of moderate exercise. 

A simple watch or phone app can cue the switches, though early Japanese volunteers used a waist‑worn beeper nicknamed JD Mate. Supportive shoes and a safe sidewalk are the only other requirements.

Proof in older adults

In a seminal five‑month experiment involving adults averaging sixty‑three years old, IWT raised VO2peak ten percent and drove systolic pressure down nine millimeters of mercury compared with either continuous walking or no exercise.

Knee strength climbed as much as seventeen percent, a critical buffer against falls. Body mass index dipped and fasting glucose improved within weeks, suggesting metabolic changes arrive quickly.

What surprised the investigators most was adherence. Ninety‑five percent of more than eight hundred participants kept the habit for the full study window.

Those who logged at least four sessions a week enjoyed the biggest gains, reinforcing the idea that consistency outranks intensity.

The pattern held over nearly two years, although adherence slipped for volunteers starting with higher waistlines.

Benefits of IWT Japanese walking

A Danish trial later pitted IWT against energy‑matched continuous walking in adults living with type 2 diabetes.

Only the interval group shrank abdominal fat and cut twenty‑four‑hour glucose fluctuations, despite similar caloric burn.

“Compared to energy‑expenditure and time‑duration matched continuous walking training, IWT is superior for improving physical fitness, body composition, and glycemic control in individuals with type 2 diabetes,” stated Karstoft.

Follow‑up mechanistic work pointed toward enhanced glucose effectiveness, meaning muscles absorbed sugar without extra insulin. 

Safety and sticking with it

Because walking remains fully aerobic, lactate rarely spikes and the risk of cardiac complications stays low. No serious adverse events surfaced across dozens of trials, even among recent joint‑replacement patients cleared by their surgeons.

Digital prompts can help sustain motivation once novelty fades. Yet data from a Danish smartphone roll‑out show that unsupervised users averaged only nine minutes of fast walking per week after a year, underscoring the value of social or clinical follow‑up.

Coaching, group strolls, or gamified leaderboards may lift engagement, particularly for people carrying extra weight.

Researchers are testing whether regular phone calls paired with step‑count feedback can duplicate laboratory adherence in the real world.

Getting started today

Consult your clinician if you have chronic conditions, then pick a flat route and set a timer for thirty minutes. Begin with one minute brisk, one minute relaxed for fifteen cycles, or even shorter bursts until comfort builds.

“Studies specifically looking at the benefits of interval walking training have found improved physical fitness, muscle strength, and glycemic control,” said Eby.

She advises ramping up gradually so each brisk interval still allows a short phrase before breath runs out.

Track sessions on a calendar; seeing streaks grow is strangely satisfying. Celebrate milestones such as a lower belt notch or an easier climb up the porch steps.

A final word for anyone who thinks walking is too gentle to matter, remember that pace, not mileage, drives adaptation.

The Japanese approach proves that swapping a few calm blocks for a confident stride can steer health markers in the right direction long before you break into a jog.

 

This is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.   

 



 

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Thursday, August 22, 2019

Glucose not responsible for inflammation in type 2 diabetes

To date, the underlying causes of inflammation in obesity and type 2 diabetes mellitus (T2DM) have been poorly understood, but a new research seems to have made a breakthrough by finding that that changes to mitochondria--the powerhouse of cells--drive chronic inflammation from cells exposed to certain types of fats, shattering the prevailing assumption that glucose was the culprit.

According to the study, chronic inflammation fuels many of the devastating complications of type 2 diabetes, including cardiovascular, kidney, periodontal diseases, and is thus one of the key targets for therapy development.

This new data may enlighten the conversation about tight glycemic control as the dominant treatment goal for people with diabetes.

Research  didn't set out to disprove the glucose-inflammation causation theory.

Based on the importance of glycolysis--a 10-reaction sequence that produces energy--in other types of inflammation, the team hypothesised those immune cells from patients with type 2 diabetes would produce energy by burning glucose. "We were wrong," he said.

"We exclusively used immune cells from human subjects for all of the work," he explained, noting that humans, but not animal models of type 2 diabetes, have the specific pro-inflammatory T cell profile her team had identified in earlier research.

The team was surprised to find that glycolysis wasn't driving chronic inflammation. Instead, a combination of defects in mitochondria and elevated fat derivatives were responsible.

Nikolajczyk said she sees applications for this research in both basic and clinical sciences. She hopes to precisely define pro-inflammatory lipid types and explore associations between circulating and/or tissue-associated lipids and insulin resistance, one key feature of Type 2 diabetes.

She is also interested in contributing to the development of new analytical approaches, spearheaded by Dr. Lauffenburger's team, that leverage ongoing lipid-related findings into a new understanding of pathology in type 2 diabetes.

"Aggressive blood glucose control to lower the risk of diabetic complications has been the goal for most people with Type 2 Diabetes for decades. Our data provide an explanation for why people with tight glucose control can nonetheless have disease progression," Nikolajczyk said.

Family history of diabetes associated with increased bone mineral density

The association between type 2 diabetes and increased fracture risk is well documented. However, little was known about the possible effect of family history of diabetes on bone mineral density (BMD). A study from China now confirms that a history of first-degree family members with diabetes is linked to increased BMD as well as to insulin resistance. Results are published online in Menopause, the journal of The North American Menopause Society (NAMS).

Because patients with type 2 diabetes are at an increased risk of fracture, understanding the early pathophysiology of altered BMD could be critical in the development of preventive strategies for diabetic osteoporosis. Although strong evidence has revealed normal to high BMD in most patients with type 2 diabetes, no data have been published, to date, that demonstrate whether BMD is altered in persons with a first-degree family history of diabetes.

In this new study involving nearly 900 normoglycemic postmenopausal women, it was found that the BMD of the lumbar spine and femoral neck was significantly higher in participants with a first-degree family history of diabetes than in those without such history, even in women with normal blood glucose levels. These same participants additionally showed increased insulin resistance and hyperinsulinemia.

"This study shows an association between a family history of diabetes and increased bone density in postmenopausal women. This finding may be related to higher insulin levels in these women with a hereditary predisposition to diabetes, because insulin has a bone-building effect. Although this sounds like good news, these women are at increased risk for developing diabetes, which is associated with skeletal fragility and increased fracture risk," says Dr. Stephanie Faubion, NAMS medical director.




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