Saturday, May 09, 2020

The Possible Weight Loss Benefits Of Oxytocin

A recent study at the Massachusetts General Hospital explored the idea of the effectiveness of a nasal spray that contains the so-called love hormone, oxytocin, as a weight loss booster, and the results are promising. Oxytocin is stated to have an appetite-suppressing effect on the brain, making you believe high-calorie foods are not satisfying.

Science aside, let’s just admit it, how convenient would it be to have a nasal spray that helps you lose weight? Continue reading to learn more about this new exciting study.


The Obesity Epidemic
Obesity has been on the rise for decades, with the World Health Organization estimating that it has nearly tripled since 1975, with over 2 billion adults worldwide suffering from excess weight. It is also a known fact that obesity is a serious health hazard, increasing the likelihood of developing heart disease, type 2 diabetes, stroke, and some types of cancer.


On top of that, excess weight takes a toll on one’s self-esteem and even budget, having you spend a lot of money to gain the desired results.


Recognizing all these negative impacts of obesity on a person’s health and wellbeing, a research team at Massachusetts General Hospital conducted an experiment that built on the previous finding that oxytocin, a hormone responsible for bonding behavior, can suppress the activity of the brain areas associated with appetitive behavior and food motivation, too.

How Can a Love Hormone Be Related to Our Appetite?
As previously mentioned, oxytocin is a hormone usually associated with social interactions, trust, sex, childbirth, and mother-infant bonding, which scientists usually sum up as ‘bonding behavior’. Apart from this realm of social interactions, it was also found that the hormone can suppress the brain pathways that make us feel anxious.


Most recently, scientists observed that oxytocin can alter the way we perceive food, too. Do you know the feeling of savoring and craving a specific kind of junk food? This feeling is often overactive in people suffering from obesity. So, theoretically, decreasing the intensity of such cravings should potentially curb the overeating habits that come with these cravings.

Oxytocin may be the component that can do this by inhibiting a key area in the reward system of the brain, which is directly-linked to the feelings of craving and satisfaction. The above-mentioned study explored this idea by looking at the brains of overweight people through an FMRI machine when they were shown pictures of high-calorie foods, low-calorie foods, and nonfood objects.


An FMRI measures the activity in certain brain regions in response to different stimuli. Usually, the reward areas in the brain of a person who is overweight will become hyperactive when they see a high-calorie object, which is observable on an FMRI image, but only an hour after receiving 1 treatment with oxytocin through a nasal spray, the participants’ brains reacted very differently: a part of the reward system called the the ventral tegmental area (VTA) became less active when patients were shown high-calorie foods.


The decreased activity in this area weakened the connectivity between the reward system and areas responsible for food motivation, which means that oxytocin did the impossible: it tricked the brain into believing junk food isn’t satisfying. Even better, of the 10 participants, none experienced any side effects from the treatment.


And though this study isn’t enough on its own to confirm the effectiveness of the treatment, it is nice to entertain the possibility of having a quick fix for weight loss very soon. And while we wait for this miracle cure, we can always increase our oxytocin levels the good old-fashioned way, through hugs and kisses.


This is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.     

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Monday, March 16, 2020

Is It Dementia or 'Medication Fog'?

As we age, the list of medications we have to take on the daily to maintain a healthy and active life begins to lengthen. At the same time, the ability of the body to compensate for the side effects of these medications decreases with age, and some medications may start making us more confused, drowsy and apathetic - a side effect known by the name ‘medication fog’.

The problem is that many patients, caregivers, and even doctors can overlook the probability of medication fog, and tend to link the above-mentioned symptoms with a neurodegenerative disease that exhibits identical symptoms - dementia. To learn more about medication fog and how to distinguish it from dementia, continue reading.

What Is Medication Fog?

Many common medications have an anticholinergic effect on the brain, meaning that they reduce or interfere with the way our nerves function. When we’re young, our nerve cells are capable of compensating for those effects, and so we don’t feel like our brain is essentially “slowing down”, but with age, we notice the effect of medication on our cognitive health more and more.

Several of these medications, even those we could previously take, can manifest themselves in the following symptoms:

    Difficulty concentrating
    Dizziness
    Confusion
    Drowsiness.

These side effects together create the medication fog.

Unfortunately, with age, one’s risk of dementia also increases, and many cases of medication side effects end up being misdiagnosed as dementia. Note that some of these medications can also worsen dementia symptoms in those who do suffer from the condition.


As you may imagine, pinpointing “medication fog” can be difficult, especially if you’re on several medications already. And most seniors are. The average American senior between the age of 65 and 69 takes 14 different prescription medications, and this number rises to 18 in the age range of 80-84. These statistics are very similar in other countries, and it makes sense because many older adults are in dire need of daily medication. However, with such a high number of pills and other treatments one needs to take daily, it becomes increasingly difficult to track the side effects of each medication.

Still, there are ways you and your doctor will be able to distinguish medication fog from dementia. To do so, ask yourself the following questions:
1. Did you start feeling worse once you started a new prescription medication or increased the dose of a medication you're used to taking?
2. Are your symptoms more pronounced shortly after you've taken an over-the-counter medicine, such as a painkiller or allergy medication?
3. Does a specific combination of medications you take on a specific day make you feel worse than usual? 

If you answered 'Yes' to any of these questions, medications may be the cause of your cognitive symptoms. Consider discussing a specific medication or a combination of medications (even if they're over-the-counter) with your doctor. They will be able to help you replace the medication in question or adjust the dosage to make you feel better.

Which Medications Are Capable of Causing Medication Fog?

Anticholinergic drugs (those that treat an overactive bladder, lung issues, excessive sweating, etc.) are the main culprit behind medication fog, according to the recently updated list of such medications by the American Geriatrics Society, but many other meds, even those available over-the-counter and nutritional supplements can cause this side effect. These medications include:

    Painkillers
    Sleep medications
    Antidepressants
    Antihistamines and allergy medications
    Muscle relaxants
    Stomach acid treatments, and others.

To access a certain drug's capacity to affect your cognitive health, you can look at the listed side effects of the medication on the leaflet that comes with the medicine or search for the information on medical apps and websites. You can also discuss the question with your doctor: simply compile a list of the meds you're currently taking (including OTC medications and supplements) and tell your doctor about the symptoms you're experiencing. Chances are that adjusting the dosage or replacing some medication could improve your cognitive health and decrease the symptoms of medication fog.
 

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