Experts Explain How Vit D Deficiency Can Cause Heart Failure

A daily dose of sunshine, which stimulates production of Vitamin D in the body, is vital not just for the well-being of your bones but may also be good for your heart.

The problem of vitamin D deficiency affecting bone health is well known for decades. For some years, scientists have also seen vitamin D deficiency as a factor that determines health of your heart. Now Indian researchers have deciphered how exactly vitamin D deficiency can cause heart failure.

The new study has shown that vitamin D deficiency alone can lead to heart failure, possibly through insulin resistance. It has found that cardiac insulin leads to functional deterioration of heart in animals with low vitamin D levels.

The utilization of glucose and fatty acids – key fuels for energy generation in heart – is adversely affected due to insulin resistance in heart cells. Insulin plays a critical role in regulation of cellular metabolism in many tissues in the body.

To study if vitamin D deficiency could cause cardiac damage similar to other risk factors like consumption of high fats and high calorie food, researchers designed an experiment with rats. They manipulated diets of animals and divided them into three groups – one with adequate vitamin D, second set had vitamin D deficiency, while the third group was fed with high fat and high fructose diet.

At the end of 20 weeks, it was found that the hearts of vitamin D deficient animals were failing. They showed molecular and functional changes similar to the hearts of rats in high fat high fructose diet group. “The cardiac dysfunction caused by vitamin D deficiency alone was very similar to that by the other risk factor – high calorie diet – sometimes even to a greater extent in some parameters. For example, cardiac inflammation was higher in vitamin D deficiency diet than high calorie diet,” researchers have observed in the study.

Researchers found greater expression of genes involved in enlargement of cardiac muscles. These findings were confirmed when scientists measured heart wall thicknesses, chamber internal diameters and contracting capacity of heart. Left ventricular posterior wall thickness was found to be increased in rats with vitamin D deficiency. This happens when cardiac workload increases and turns pathological if no remedial measures are taken, finally progressing to heart failure. In such condition, the pumping action of the heart can no longer meet the metabolic demands of the body.

“We have shown the link between vitamin D deficiency and cardiac dysfunction and how it may lead to heart failure. Vitamin D and its signalling modulate myocardial insulin sensitivity, the insufficiency of which induces impaired glucose utilization, remodeling response, and heart failure,” explained a senior scientist.

The group, in its study in 2016 involving a South Indian population, had shown that low vitamin D levels were associated with diabetes as well as diabetes plus coronary artery disease. However, it had not provided any cause-effect relationship. “Our study now tackles exactly that issue with animal experiments and provides conclusive evidence,” Dr. added.

The new findings have both public health and therapeutic implications. The insights gained on how vitamin D signalling affects myocardial insulin sensitivity may help scientists design new drugs for management of heart failure by targeting activation of vitamin D receptor.

With vitamin D deficiency emerging as a risk factor for heart disease, public health policies will have to take note of it since metabolic disorders are already a major health challenge in India. “We have evidence to show that widespread vitamin D deficiency in Indians definitely contributes to insulin resistance and diabetes. Our previous research and ongoing work in Indian population have indicated that supplementation with vitamin D may help in ameliorating insulin resistance and decreasing blood glucose levels,” commented a Dr.

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Health Benefits of Avocado

Avocado is rich in monounsaturated fats, which make its texture creamy and smooth.
Compared to most other fruits, avocado is much higher in fat.
Avocado can be said to have a unique nutrition profile if you take into consideration the fact that it contains a lot of fiber, vitamins and minerals such as vitamin K, vitamin E, vitamin C and B-vitamins, potassium, and copper.
The consumption of avocado has been linked with numerous health benefits and one of them is the reduced risk of cardiovascular disease.
Due to its potent nutritional profile, it is very satiating, thus helpful for weight loss.
As for eating avocado, it can be eaten raw, but can also be prepared and used in foods such as guacamole.

1) Aids in Digestion
It is believed that avocados are soothing for the intestine and therefore aid digestion. They contain soluble and insoluble fibers that help to keep the digestive system working smoothly. These types of fiber are very important for digestion because they bulk up stools and help ensure the smooth passage of food through the intestinal tract. Furthermore, they stimulate gastric and digestive juices so nutrients are absorbed in the most efficient and rapid way. Finally, they reduce the symptoms from conditions like constipation and diarrhea. All in all, the huge amount of fiber found in avocados (40% of daily requirement per serving) makes this a very important food for optimizing your digestive health.

2)Dental Care

Consumption of avocados also helps in preventing bad breath, which is primarily caused due to indigestion or an upset stomach. Halitosis can be eliminated by improving digestive health, and the antibacterial and antioxidant flavonoids found in avocados also kill the bacteria in your mouth that can result in bad breath. Avocados have also been connected with preventing oral cancers!

Skin and Hair Care

Avocados are packed with nutrients that are beneficial for maintaining healthy skin. It enriches skin that is dry, chapped or damaged. They are added to a variety of cosmetics due to their ability to nourish the skin with essential vitamins and make it glow. It is also used for nourishing dry and damaged hair. Many people use avocados to prepare skin and hair masks. Above all, avocado oil helps in treating plaque psoriasis. Beta-carotene and lycopene are two organic compounds found in large quantities in avocados. Both of these have been connected to improving the health and tone of your skin and eliminating signs of premature aging.

Liver Care

Avocados are very good at reducing liver damage. It has certain organic compounds that help in improving liver health. Liver damage is normally caused due to Hepatitis C. Findings of a recent research study suggest that avocados may play a major role in toning up and protecting your liver from a wide variety of conditions.

Improves Vision

Avocados help keep your eyes healthy. They contain carotenoids such as lutein and zeaxanthin, which help to protect your eyes against cataracts, eye diseases related to age, and macular degeneration. These conditions are often caused by free radicals that accumulate in the tissues of the eyes. The antioxidant activity of these special carotenoids in avocados neutralize the effects of those dangerous free radicals.

Promotes Healthy Heart

The health benefits of avocados include a healthier heart. Beta-sitosterol, which is found in avocados, helps maintain healthy cholesterol levels. Research studies suggest that the intake of avocado may enhance antiatherogenic properties of HDL cholesterol, which helps in protecting the heart from atherosclerosis, also known as arteriosclerotic vascular disease. The significant levels of potassium also make avocados a powerful fruit in the fight against hypertension. Potassium is a vasodilator, which relaxes the tension of blood vessels and arteries, thereby reducing the chances of clotting, heart attacks, and strokes.

Kidney Health

Diet plays a very important role in maintaining the balance of minerals and fluids in those who suffer from chronic kidney disorders. Potassium is one of the minerals that help in maintaining a normal heart rate. Avocados are a good source of potassium and their inclusion in your diet may provide other benefits as well. It is important to make sure that potassium levels are not too high as that can also be dangerous for the heart. Potassium is a key aspect of maintaining fluid balance through chemical channels for cells and organs. This balance of fluid is also vital for the functioning of the kidney, which handles the movement of fluid and toxins through the body.

Vitamin K Deficiency

A vitamin K deficiency is not very common but is frequently seen in neonatal care. It may lead to a bleeding disorder known as vitamin K deficiency-related bleeding (VKDB). This occurs mostly due to an insufficient intake of vitamin K during pregnancy. The inclusion of avocado in the diet of a pregnant woman may help in lowering risk of VKDB in the newborn child since avocados are one of the rare fruits that have a very high amount of vitamin K (almost 40% of the daily requirement in a single serving!)

Morning Sickness

During pregnancy, morning sickness is very common. Avocados help overcome nausea and queasiness during pregnancy since it contains Vitamin B6, which is commonly connected to reducing nausea and vomiting.

Treats Arthritis

The anti-inflammatory properties of avocados are perhaps its most valuable attribute, and between the wide range of phytochemicals, flavonoids, carotenoids, phytosterols, fatty alcohols, and omega-3 fatty acids it contains, avocados are one of the best foods for reducing the inflammation in tissues, joints, and muscles. Arthritis affects tens of millions of people around the world, and by consuming a proper amount of avocados, studies have frequently shown the symptoms and associated pain of arthritis can be efficiently reduced!

Anti-cancer Properties

Health benefits of avocados include a lower risk of cancers, including breast cancer and prostate cancer. Avocado contains carotenoids and monounsaturated fat, both of which contribute to the significant reduction of cancer. Avocado also contains Glutathione, an antioxidant that protects the cells from cancer and the dangerous effects of free radicals. The list of antioxidant and anti-inflammatory compounds in avocados is impressive, and it is almost difficult to determine which one has the largest impact. Studies have been widely done on oral, skin, and prostate cancers, and the results show that instead of metastasizing, the organic compounds in avocados cause cancerous cells to undergo apoptosis (automatic cell death). Research is still ongoing on the relationship between avocados and cancer.

Antioxidant Properties

Avocado contains both vitamin C and E, which help enhance antioxidant properties of the human body. Vitamin C recycles Vitamin E and helps reduce the oxidation of LDL cholesterol. Avocado also contains antioxidants like epicatechin, violaxanthin, neochrome, and about a dozen others. Antioxidants neutralize the effects of free radicals, the dangerous byproducts of cellular metabolism. They are responsible for dozens of serious conditions in the body, including cancer, cardiovascular disease, vision problems, premature aging, cognitive disorders, and many more.

Healthy Skin

Avocados contain many vitamins and minerals that help in maintaining healthy skin. Carotenoids  found in avocados are associated with reducing UV-induced inflammation of the skin due to exposure to the sun. Oil made from avocado helps in protecting the skin against sunburn damage. The high levels of beta-carotene in avocados can be enzymatically split into pro-vitamin A, which has long been connected to protecting the skin from a variety of conditions and the damaging effects of the sun.

Weight Management

Regular exercise, along with a healthy diet, is very important in weight management. Avocados are fruits that provide nutritional value to the body and support weight control. Findings of a recent study suggest a number of beneficial effects of avocado on weight management.

Anti-aging

Consuming avocados is also associated with healthy aging. It contains compounds such as xanthophyll, which has antioxidant properties. Research studies suggest that an intake of xanthophyll may decrease signs of the aging process on various parts of your body.

Strengthens Bones

Avocados contain carotenoids such as zeaxanthin and lutein, which are associated with a reduced risk of cartilage defects (the symptom of osteoarthritis). Intake of foods such as avocado and soy may help in reducing the risk of osteoarthritis. Furthermore, the levels of essential minerals in avocados are significant, including zinc, phosphorous, copper, and trace amounts of calcium and selenium. All of these are connected to lowered risks of osteoporosis and improvements in bone mineral density.

Nutrient Absorption

Avocados are best eaten along with other fruits and vegetables. This is due to the fact that nutrients present in fruits and vegetables get enhances when eaten along with avocados. The absorption of carotenoid antioxidant molecules, which helps protect the body against free radical damage, increases three to five times when a salad is eaten along with avocado. Therefore, adding sliced avocado to a mixed salad is a good way to make a healthy meal even better. This makes avocado a great element as an appetizer since it prepares the digestive tract to function at its highest level during the meal to come!

Blood Glucose Level

Apart from the fruit, the leaf extracts of avocados also provide health benefits. A study conducted on non-diabetic and diabetic rats suggest that the leaf extracts may help in lowering blood glucose levels. For diabetic patients, the metabolism of starch-based foods into simple sugars like glucose can cause the spikes and plunges that are dangerous for diabetics. Fiber helps to slow the breakdown of food into usable sugars, so it is absorbed by the body in a more balanced way. Furthermore, the majority of carbohydrates in avocados are made up of 7-carbon sugars, a relatively rare form of sugar that actually inhibit the enzyme hexokinase. This helps avocados control the way that glucose is metabolized by the body, thereby protecting the overall health of diabetic patients.

Useful for Athletes

Athletes require a lot of energy and must maintain optimal nutrition to fuel their body. Avocado provides vital nutrients to athletes to maintain required energy levels and good health. Moreover, they contain phytochemicals that are a natural fuel source for your body.

Side Effects of Avocado

The side effects of consuming too much of avocado include:

• Migraine
• Nausea
• Vomiting
• Sensitivity to light

Care must be taken and consumption of avocado should be avoided if these symptoms are experienced.

How to Select and Store Avocado?

Fresh, ripe avocados with no dark spots should be chosen. Do not refrigerate avocados unless they are ripe. If a portion of the fruit has been used then the remainder may be stored in the refrigerator for future use. Unripe avocados can be stored at room temperature.

 THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.                                                                                                                                                                                                      PS- THOSE INTERESTED IN RECIPES ARE FREE TO VIEW MY BLOG-                                                                                           https://gseasyrecipes.blogspot.com/   
FOR INFO ABOUT KNEE REPLACEMENT, YOU CAN VIEW MY BLOG-                                                           https:// kneereplacement-stickclub.blogspot.com/                              
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