Tuesday, June 01, 2021

BTOX: Testing Yourself for Dangerous Toxins and GI Diseases

Health and medicine used to be much harder. Doctors were actually operating in the dark, never knowing about the world of cells, viruses, and bacteria. Today, the world of medicine is a very different one. Doctors now have thousands of tests to determine what's wrong with us.
 
One of the biggest problems with detection, however, even in this age, is that all the tests are done at clinics and hospitals, meaning we the person must first DETECT a problem or a symptom with ourselves. Often, by the time a symptom manifests strongly enough for us to finally realize something is truly wrong - the problem has already gotten much, much worse. 
 
 For example, take the case of stomach problems. Did you know over 52% of people over the age of 40 report suffering from CONTINUOUS gut and stomach pain or discomfort? That percent continues to climb as we advance in age. Most of us just shrug it off and blame food or bad digestion. We try to vary our diet and tell ourselves the discomfort is a bit better while most of the time it continues.
Common symptoms that occur continuously can be bloating, constipation, diarrhea, Crohn's Disease, IBS and other digestive issues we deal with. The biggest problem is these GI problems are linked to other issues such as skin conditions and autoimmune disease or even psychological disorders such as anxiety and depression. The stomach is a nerve center and can affect the rest of the body in a thousand different ways.

We're fortunate though because we live at an age where medical tests are now starting to be offered as home kits. These kits can be ordered and easily performed at home, allowing us to find medical problems we didn't even know we had, and at a much earlier stage. 
 
Years of eating food left in the open and food that has gone through unwashed hands or just unlucky enough to be near toxins at some point. Most of these toxins get washed away with our urine, but a certain group of toxins do not go anywhere but sink into your guts and stomach, staying and building up in your body.

For GI problems, we now have tests that can be taken at home. These tests are called BTOX tests and they give actual clarity about the situation in your gut by screening it and identifying the exact food sensitivities that trigger your autoimmune and chrnoic illnesses. The test provides you with a crucial list of foods are good for your personal digestive system and those that are destroying on your guts – and that should be avoided at all costs. 
 
This is something we highly recommend doing for yourself and the adults in your family. You receive a home test you can conduct easily on your own, then you just fill up a questionnaire and send it back with your collected sample in order to receive a full analysis of your biochemistry, warning as to potential problems, and a nutritional plan designed individually to correct the issue. It's never too early to catch something that may affect your entire life unless stopped. The BTOX test comes with a detailed nutritional plan after finding out what exactly is wrong with your GI.

This is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.   

https://gscrochetdesigns.blogspot.com. one can see my crochet creations  
https://gseasyrecipes.blogspot.com. feel free to view for easy, simple and healthy recipes    
https://kneereplacement-stickclub.blogspot.com. for info on knee replacement

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Saturday, January 18, 2020

Ingestible medical devices can be broken down with light

A variety of medical devices can be inserted into the gastrointestinal tract to treat, diagnose, or monitor GI disorders. Many of these have to be removed by endoscopic surgery once their job is done. However, MIT engineers have now come up with a way to trigger such devices to break down inside the body when they are exposed to light from an ingestible LED.

The new approach is based on a light-sensitive hydrogel that the researchers designed. Incorporating this material into medical devices could avoid many endoscopic procedures and would give doctors a faster and easier way to remove devices when they are no longer needed or are not functioning properly, the researchers say. 

"We are developing a set of systems that can reside in the gastrointestinal tract, and as part of that, we're looking to develop different ways in which we can trigger the disassembly of devices in the GI tract without the requirement for a major procedure," says Giovanni Traverso, an assistant professor of mechanical engineering, a gastroenterologist at Brigham and Women's Hospital, and the senior author of the study.

In a study in pigs, the researchers showed that devices made with this light-sensitive hydrogel can be triggered to break down after being exposed to blue or ultraviolet light from a small LED. 

Ritu Raman, a postdoc at MIT's Koch Institute for Integrative Cancer Research, is the lead author of the paper, which appears today in Science Advances. Other authors of the paper are former technical associates Tiffany Hua, Jianlin Zhou, Tina Esfandiary, and Vance Soares; technical associates Declan Gwynne, Joy Collins, and Siddartha Tamang; graduate student Simo Pajovic; Division of Comparative Medicine veterinarian Alison Hayward; and David H. Koch Institute Professor Robert Langer.

Controlled breakdown
Over the past several years, Traverso and Langer have developed many ingestible devices designed to remain in the GI tract for extended periods of time. They have also worked on a variety of strategies to control the breakdown of such devices, including methods based on changes in pH or temperature, or exposure to certain chemicals. 

"Given our interests in developing systems that can reside for prolonged periods in the gastrointestinal tract, we continue to investigate a range of approaches to facilitate the removal of these systems in the setting of adverse reaction or when they are no longer needed," Traverso says. "We're really looking at different triggers and how they perform, and whether we can apply them to different settings."

In this study, the researchers explored a light-based trigger, which they believed could offer some advantages over their earlier approaches. One potential advantage is that light can act at a distance and doesn't need to come into direct contact with the material being broken down. Also, light normally does not penetrate the GI tract, so there is no chance of accidental triggering. 

To create the new material, Raman designed a light-sensitive hydrogel based on a material developed in the lab of Kristi Anseth, a former Langer lab postdoc who is now a professor of chemical and biological engineering at the University of Colorado at Boulder. This polymer gel includes a chemical bond that is broken when exposed to a wavelength of light between 405 and 365 nanometers (blue to ultraviolet). 

Raman decided that instead of making a material composed exclusively of that light-sensitive polymer, she would use it to link together stronger components such as polyacrylamide. This makes the overall material more durable but still allows it to break apart or weaken when exposed to the right wavelength of light. She also constructed the material as a "double network," in which one polymer network surrounds another.

"You're forming one polymer network and then forming another polymer network around it, so it's really entangled. That makes it very tough and stretchy," Raman says.

The material's properties can be tuned by varying the composition of the gel. When the light-sensitive linker makes up a higher percentage of the material, it breaks down faster in response to light but is also mechanically weaker. The researchers can also control how long it takes to break down the material by using different wavelengths of light. Blue light works more slowly but poses less risk to cells that are sensitive to damage from ultraviolet light.

Deflated by light
The gel and its breakdown products are biocompatible, and the gel can be easily molded into a variety of shapes. In this study, the researchers used it to demonstrate two possible applications: a seal for a bariatric balloon and an esophageal stent. Standard bariatric balloons, which are sometimes used to help treat obesity, are inflated in a patient's stomach and filled with saline. After about six months, the balloon is removed by endoscopic surgery.

In contrast, the bariatric balloon that the MIT team designed can be deflated by exposing the seal to a tiny LED light, which would in principle be swallowed and then pass out of the body. Their balloon is made of latex and filled with sodium polyacrylate, which absorbs water. In this study, the researchers tested the balloons in pigs and found that the balloons swelled up as soon as they were placed in the stomach. When a small, ingestible LED emitting blue light was placed in the stomach for about six hours, the balloons slowly deflated. With a higher-power light, the material broke down within 30 minutes.

The researchers also molded the light-sensitive gel into an esophageal stent. Such stents are sometimes used to help treat esophageal cancer or other disorders that cause a narrowing of the esophagus. A light-triggerable version could be broken down and passed through the digestive tract when no longer needed. 

In addition to those two applications, this approach could be used to create other kinds of degradable devices, such as vehicles for delivering drugs to the gastrointestinal tract, according to the researchers. 

"This study is a proof of concept that we can create this kind of material, and now we're thinking about what are the best applications for it," Traverso says.

This is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.     
https://gscrochetdesigns.blogspot.com. one can see my crochet creations  
https://gseasyrecipes.blogspot.com. feel free to view for easy, simple and healthy recipes    
https://kneereplacement-stickclub.blogspot.com. for info on knee replacement
 

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Friday, December 20, 2019

BTOX: Testing Yourself for Dangerous Toxins and GI Diseases

Health and medicine used to be much harder. Doctors were actually operating in the dark, never knowing about the world of cells, viruses, and bacteria. Today, the world of medicine is a very different one. Doctors now have thousands of tests to determine what's wrong with us.

One of the biggest problems with detection, however, even in this age, is that all the tests are done at clinics and hospitals, meaning we the person must first DETECT a problem or a symptom with ourselves. Often, by the time a symptom manifests strongly enough for us to finally realize something is truly wrong - the problem has already gotten much, much worse.

For example, take the case of stomach problems. Did you know over 52% of people over the age of 40 report suffering from CONTINUOUS gut and stomach pain or discomfort? That percent continues to climb as we advance in age. Most of us just shrug it off and blame food or bad digestion. We try to vary our diet and tell ourselves the discomfort is a bit better while most of the time it continues.

Common symptoms that occur continuously can be bloating, constipation, diarrhea, Crohn's Disease, IBS and other digestive issues we deal with. The biggest problem is these GI problems are linked to other issues such as skin conditions and autoimmune disease or even psychological disorders such as anxiety and depression. The stomach is a nerve center and can affect the rest of the body in a thousand different ways.

We're fortunate though because we live at an age where medical tests are now starting to be offered as home kits. These kits can be ordered and easily performed at home, allowing us to find medical problems we didn't even know we had, and at a much earlier stage.
Years of eating food left in the open and food that has gone through unwashed hands or just unlucky enough to be near toxins at some point. Most of these toxins get washed away with our urine, but a certain group of toxins do not go anywhere but sink into your guts and stomach, staying and building up in your body. 

For GI problems, we now have tests that can be taken at home. These tests are called BTOX tests and they give actual clarity about the situation in your gut by screening it and identifying the exact food sensitivities that trigger your autoimmune and chrnoic illnesses. The test provides you with a crucial list of foods are good for your personal digestive system and those that are destroying on your guts – and that should be avoided at all costs. 

his is something we highly recommend doing for yourself and the adults in your family. You receive a home test you can conduct easily on your own, then you just fill up a questionnaire and send it back with your collected sample in order to receive a full analysis of your biochemistry, warning as to potential problems, and a nutritional plan designed individually to correct the issue. It's never too early to catch something that may affect your entire life unless stopped. The BTOX test comes with a detailed nutritional plan after finding out what exactly is wrong with your GI.

this is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.     
https://gscrochetdesigns.blogspot.com. one can see my crochet creations  
https://gseasyrecipes.blogspot.com. feel free to view for easy, simple and healthy recipes    
https://kneereplacement-stickclub.blogspot.com. for info on knee replacement
  
 
  

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