Saturday, May 23, 2020

FDA Warning Says the Chemicals in Sunscreen Can Be Absorbed In Your Bloodstream—Here's What That Means


We know you’ve been told all your life to slather on the sunscreen before a day spent outside. We’re not disputing that advice, but a new report in the Journal of the American Medical Association has given us some food for thought: There’s a chance that sunscreen could potentially be dangerous.

Here’s how: Sunscreen ingredients can travel through the skin and build up in the bloodstream, the new report suggests. This finding has raised concerns about how sunscreen might affect reproductive and developmental health and whether it can cause cancer, according to an editorial accompanying the new report.

For the new study, scientists from the U.S. Food and Drug Administration (FDA) studied the effects of sunscreen on 24 healthy people. They tested four different sunscreens—two sprays, one lotion, and one cream—each applied four times a day, to 75% of the body surface, for four days.

Blood samples were then taken from the participants to determine how much of four specific sunscreen ingredients—avobenzone, oxybenzone, ecamsule, and octocrylene—ended up in their bloodstreams. And it turns out, it was a significant amount.

A bit of background: The FDA recommends that any active ingredients in sunscreen with “systemic absorption greater than 0.5 ng/mL” should undergo toxicology studies, including research on developmental, reproductive, and cancer-related health issues. And sure enough, all four of those ingredients were found at levels greater than that FDA benchmark—some at levels six or even eight times higher.

That certainly sounds concerning. But before we freak out about how much sunscreen we’ve been putting on for the last 10 years, let’s consider a few key aspects of this new research. First, the number of participants evaluated—24—is quite low, and the results only showed blood levels of these chemicals over the course of one week.

Second, the report isn’t claiming that these chemicals are actually unsafe, or that sunscreen should be pulled from supermarket shelves. In fact, it doesn’t even recommend throwing your sunscreen out. “These results do not indicate that individuals should refrain from the use of sunscreen,” it says.

What the report does say is that we need to know more. “The systemic absorption of sunscreen ingredients supports the need for further studies to determine the clinical significance of these findings,” the authors wrote. The accompanying editorial points out that further testing could be especially important for babies, “whose skin may absorb substances at differential rates.”

The editorial also calls for sunscreen manufacturers to commit to more safety tests, claiming that industry leaders have been hesitant to do so in the past. “Despite multiple efforts by the FDA to persuade sunscreen manufacturers to conduct key safety studies, the manufacturers have failed to produce such data, forcing the FDA to conduct its own studies,” the editorial states.

Those FDA studies haven’t been super promising, either: In 2014, an advisory panel concluded that there wasn’t enough evidence to state unequivocally that certain sunscreen ingredients are safe.

Dermatologists, however, still say that lathering up before spending time outdoors is a must—despite these new concerns. “Sunscreen is one of the major components of sun protection,” Noelani González, MD, an instructor of dermatology at the Mount Sinai Icahn School of Medicine in New York City, tells Health. According to the Skin Cancer Foundation, daily use of a sunscreen with SPF 15 or higher reduces the risk of developing melanoma—the deadliest form of skin cancer—by 50%.
Plus, says Dr. González, no clinical studies have actually linked sunscreen use to any of the potential dangers mentioned in this new study. “At this point we don’t necessarily know that [the ingredients analyzed in the new report] are worrisome,” she says. “It’s a very good starting point for us as physicians to investigate, but it’s early on.”

So what does this mean for you when you’re packing your beach bag? You should definitely still throw in the sunscreen. If you’re concerned about ingredients like oxybenzone, you might want to consider products with physical or mineral blockers (rather than chemical blockers) like zinc oxide and titanium dioxide, which aren’t absorbed by the skin and are considered safe by the FDA.

But until we know more, says Dr. González, any sunscreen is still better than none at all. The authors of the editorial agree, saying that avoidance of sunscreen as a result of this study “could have significant health implications.” They also point out that wearing sunscreen should be just one part of a larger sun-protection plan—one that also includes wearing protective clothing, hats, and sunglasses when spending time outside, and seeking shade when the sun is strongest.

This is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.     

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Thursday, December 06, 2018

Artificial synapses made from nanowires

Scientists have produced a memristive element made from nanowires that functions in much the same way as a biological nerve cell. The component is able to save and process information, as well as receive numerous signals in parallel. The resistive switching cell made from oxide crystal nanowires is thus an ideal candidate for use in building bioinspired "neuromorphic" processors, able to take over the diverse functions of biological synapses and neurons.

Computers have learned a lot in recent years. Thanks to rapid progress in artificial intelligence they are now able to drive cars, translate texts, defeat world champions at chess, and much more besides. In doing so, one of the greatest challenges lies in the attempt to artificially reproduce the signal processing in the human brain. In neural networks, data are stored and processed to a high degree in parallel. Traditional computers, on the other hand, rapidly work through tasks in succession and clearly distinguish between the storing and processing of information. As a rule, neural networks can only be simulated in a very cumbersome and inefficient way using conventional hardware.

Systems with neuromorphic chips that imitate the way the human brain works offer significant advantages. These types of computers work in a decentralised way, having at their disposal a multitude of processors, which, like neurons in the brain, are connected to each other by networks. If a processor breaks down, another can take over its function. What is more, just like in the brain, where practice leads to improved signal transfer, a bioinspired processor should have the capacity to learn.

"With today's semiconductor technology, these functions are to some extent already achievable. These systems are, however, suitable for particular applications and require a lot of space and energy," says a Dr. Our nanowire devices made from zinc oxide crystals can inherently process and even store information, and are extremely small and energy efficient."

For years, memristive cells have been ascribed the best chances of taking over the function of neurons and synapses in bioinspired computers. They alter their electrical resistance depending on the intensity and direction of the electric current flowing through them. In contrast to conventional transistors, their last resistance value remains intact even when the electric current is switched off. Memristors are thus fundamentally capable of learning.

In order to create these properties, scientists used a single zinc oxide nanowire, produced by their colleagues from the polytechnic university. Measuring approximately one 10,000th of a millimeter in size, this type of nanowire is over 1,000 times thinner than a human hair. The resulting memristive component not only takes up a tiny amount of space, but is also able to switch much faster than flash memory.

Nanowires offer promising novel physical properties compared to other solids and are used among other things in the development of new types of solar cells, sensors, batteries and computer chips. Their manufacture is comparatively simple. Nanowires result from the evaporation deposition of specified materials onto a suitable substrate, where they practically grow of their own accord.

In order to create a functioning cell, both ends of the nanowire must be attached to suitable metals, in this case platinum and silver. The metals function as electrodes, and in addition, release ions triggered by an appropriate electric current. The metal ions are able to spread over the surface of the wire and build a bridge to alter its conductivity.

Components made from single nanowires are, however, still too isolated to be of practical use in chips. Consequently, the next step being planned by the  researchers is to produce and study a memristive element, composed of a larger, relatively easy to generate group of several hundred nanowires offering more exciting functionalities.

THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.                                                                                                                                                                                                                                                                                        PS- THOSE INTERESTED IN RECIPES ARE FREE TO  VIEW MY BLOG-                                                                                           https://gseasyrecipes.blogspot.com/                                                                                                                                                                             FOR INFO ABOUT KNEE REPLACEMENT, YOU CAN VIEW MY BLOG-                                                                                                                             https:// kneereplacement-stickclub.blogspot.com/                                                                                       FOR CROCHET DESIGNS                                                                                                                                                                                                                                 https://gscrochetdesigns.blogspot.com

 

 

 

 

 

 

 

n. As a rule, neural networks can only be simulated in a very cumbersome and inefficient way using conventional hardware.
Systems with neuromorphic chips that imitate the way the works offer significant advantages. These types of computers work in a decentralised way, having at their disposal a multitude of processors, which, like neurons in the brain, are connected to each other by networks. If a processor breaks down, another can take over its function. What is more, just like in the brain, where practice leads to improved signal transfer, a bioinspired processor should have the capacity to learn.
"With today's semiconductor technology, these functions are to some extent already achievable. These systems are, however, suitable for particular applications and require a lot of space and energy," says Dr. Ilia Valov from Forschungszentrum Jülich. "Our nanowire devices made from zinc oxide crystals can inherently process and even store information, and are extremely small and energy efficient."
For years, memristive cells have been ascribed the best chances of taking over the function of neurons and synapses in bioinspired computers. They alter their electrical resistance depending on the intensity and direction of the electric current flowing through them. In contrast to conventional transistors, their last resistance value remains intact even when the electric current is switched off. Memristors are thus fundamentally capable of learning.
In order to create these properties, scientists at Forschungszentrum Jülich and RWTH Aachen University used a single zinc oxide nanowire, produced by their colleagues from the polytechnic university in Turin. Measuring approximately one 10,000th of a millimeter in size, this type of nanowire is over 1,000 times thinner than a human hair. The resulting memristive component not only takes up a tiny amount of space, but is also able to switch much faster than flash memory.
Nanowires offer promising novel physical properties compared to other solids and are used among other things in the development of new types of solar cells, sensors, batteries and computer chips. Their manufacture is comparatively simple. Nanowires result from the evaporation deposition of specified materials onto a suitable substrate, where they practically grow of their own accord.
In order to create a functioning cell, both ends of the nanowire must be attached to suitable metals, in this case platinum and silver. The metals function as electrodes, and in addition, release ions triggered by an appropriate electric current. The metal ions are able to spread over the surface of the wire and build a bridge to alter its conductivity.
Components made from single are, however, still too isolated to be of practical use in chips. Consequently, the next step being planned by the Jülich and Turin researchers is to produce and study a memristive element, composed of a larger, relatively easy to generate group of several hundred nanowires offering more exciting functionalities.


Read more at: https://phys.org/news/2018-12-artificial-synapses-nanowires.html#jCp

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Wednesday, April 11, 2018

Canned foods may harm your digestive system

Do you like canned foods such as corn, tuna, asparagus or chicken? If yes, then think twice before consuming it. A team of researchers have warned that the canned foods may contain zinc oxide that can damage your digestive system.

The study showed that nanoparticles of zinc oxide present in the lining of certain canned goods, usually considered good for its antimicrobial properties and preventing staining of sulfur-producing foods, may negatively affect the way in which human digestive tract operates. 

An Associate Professor  said,"We found that zinc oxide (ZnO) nanoparticles at doses that are relevant to what you might normally eat in a meal or a day can change the way that your intestine absorbs nutrients or your intestinal cell gene and protein expression." 

Researchers found that canned food contained 100 times the daily dietary allowance of zinc. 

The  Prof. added,"They tend to settle onto the cells representing the gastrointestinal tract and cause remodelling or loss of the microvilli, which are tiny projections on the surface of the intestinal absorptive cells that help to increase the surface area available for absorption." 

This loss of surface area tends to result in a decrease in nutrient absorption.

Researchers said that some of the nanoparticles also cause pro-inflammatory signalling at high doses, and this can increase the permeability of the intestinal model.

In other words, it can even allow the passage of compounds that are not supposed to pass through into the bloodstream.

The study looked at how many particles might be transferred into the canned food.

"Our model shows that the nanoparticles do have effects on our in vitro model, and that understanding how they affect gut function is an important area of study for consumer safety," the Prof. said.

THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.                                                                                                                                                                                                      PS- THOSE INTERESTED IN RECIPES ARE FREE TO VIEW MY BLOG-                                                                                           https://gseasyrecipes.blogspot.com/   
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