This mobile game may help detect Alzheimer's risk

A specially designed smartphone game can detect people at the risk of developing Alzheimer's say researchers.

The game called Sea Hero Quest, downloaded and played over 4.3 million people worldwide, helped researchers better understand dementia by seeing how the brain works in relation to spatial navigation.

Dementia will affect 135 million people worldwide by 2050. We need to identify people to reduce their risk of developing dementia, said lead researcher.

As players made their way through mazes of islands and icebergs, the research team translated every 0.5 seconds of game-play into scientific data. The team studied how people who are genetically pre-disposed to Alzheimer's play the game compared with those who are not.

The results, showed people genetically at risk of developing Alzheimer's can be distinguished from those who are not on specific levels of the Sea Hero Quest game.

The findings are particularly important because a standard memory and thinking test cannot distinguish between the risk and non-risk groups. Our findings show we can reliably detect such subtle navigation changes in at-genetic-risk of Alzheimer's compared with healthy people without any symptoms or complaints, said the researcher.

The team studied gaming data taken from 27,108 UK players, aged 50-75 years and the most vulnerable age-group to develop Alzheimer's in the next decade. They compared this benchmark data with a smaller lab-based group of 60 people who underwent genetic testing.

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A specially designed smartphone game can detect people at t ..

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Virtual reality helps stroke survivors improve memory

Researchers over at the University of Canterbury have showed through their study that there exists a possible treatment that could enable care takers to improve memory of stroke survivors.

University of Canterbury Professor Tanja Mitrovic said that one of the crucial points for those who have suffered from stroke is to improving prospective memory — the ability to remember to perform actions in the future. Mitrovic added, “This kind of memory is often impaired in stroke survivors and can interfere with independent living, as it can result in forgetting to take medication or remember something they had to do.”

Classifying it as a complex cognitive ability, Mitrovic said that it requires coordination of multiple cognitive abilities including spatial navigation, retrospective memory, attention and executive functioning.
 
To address this, the researchers developed a computer-based treatment based on visual imagery that taught participants how to remember time and event-based prospective memory tasks. After the treatment, participants practiced their skills using videos first and later in a 3D virtual reality environment.

“We conducted a study which ended in October last year with 15 stroke survivors. Each participant had 10 individual sessions spread over 10 weeks. The analysis shows that the memory skills of the stroke patients we tested increased significantly,” said Mitrovic.

The final goal was to make the training available freely over the internet to stroke survivors, enabling them to lead a better quality life and freeing some of them from round-the-clock care.

 The research team is now planning for a larger clinical study to explore the effect of similar treatment on brain-injury patients.
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