Saturday, February 03, 2018

Exercising regularly reduces complications post-lung cancer surgery by 48%

Exercising regularly before undergoing surgery for lung cancer may reduce the complication rate by half afterwards, a study has found.

Pooled analysis of the data showed that an exercise programme before surgery reduces the complication rate afterwards by 48 per cent.
 
It also reduced length of hospital stay by nearly three days for patients with lung cancer, according to the study.

"Postoperative complication is a major concern for patients undergoing [cancer] surgery," said a Dr.

"The findings may also impact on healthcare costs and on patients' quality of life, and consequently have important implications for patients, healthcare professionals and policy makers," he said.

The researchers trawled databases for relevant studies and found 17 suitable articles which reported on 13 clinical trials, involving 806 participants and six different types of cancer: bowel, liver, gullet (esophageal), lung, mouth and prostate.

The exercise programmes, which were compared with standard care or advice, lasted from one to four weeks, with the average length a fortnight.

Trials that reported more numerous sessions of exercise had better results, suggesting that there may be a dose response effect, the researchers said.

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Monday, October 23, 2017

A new medication that could help treat postoperative shivering

A new study suggests that postoperative shivering can be reduced by acetaminophen.

Acetaminophen, such as Tylenol which is a pain reliever and a fever reducer, its intake during surgery may reduce the incidence of postoperative shivering. It is a common side effect that a patient happens to suffer chills and shivering while regaining consciousness after surgery. Shivering can occur in up to half of patients. While the exact cause is unknown, scientists believe it may be related to the body cooling down.

Lead study author, a physician anesthesiologist said, "Postoperative shivering is a frequent complication in patients recovering from general anesthesia. It causes significant pain and discomfort."

"Postoperative shivering can also put a strain on the cardiovascular system, therefore we need to prevent it, especially in patients with cardiopulmonary risk," Dr. added. She also noted that acetaminophen is being used more and more pre- and postoperatively in an effort to control pain and to minimize opioids.

However, until now, few studies have evaluated the ability of acetaminophen to prevent postoperative shivering. The study was conducted on 37 patients who were scheduled for gynecologic surgery. 

They were randomly assigned to receive acetaminophen (15 mg per kilogram of body weight) intravenously, or a placebo, after receiving general anesthesia. Among the women who received acetaminophen, 22.2 percent experienced postoperative shivering, compared to 73.7 percent of those who received the placebo.

Moreover, the severity of shivering was significantly lower among women who received acetaminophen. Their body temperature was significantly lower 30 minutes after researchers began their postoperative observation in the recovery room among patients who received acetaminophen compared to those who received the placebo. "We believe our findings can be widely applicable, as acetaminophen is a relatively safe drug and commonly used," Dr.  stated.

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