Vitamin C May Help Halt the Progression of Blood Cancer

According to a latest study conducted by the experts at the New York University, vitamin C injections may help kill faulty cells present in the bone marrow, this can help plateau the growth of cancer cells in blood. Such cancers cause anemia, infection risk, and bleeding as abnormal stem cells multiply in the bone marrow until they interfere with blood cell production. "We are excited by the prospect that high-dose vitamin C might become a safe treatment for blood diseases caused by TET2-deficient leukemia stem cells, most likely in combination with other targeted therapies," said a Prof.

Vitamin C has long been associated with strengthening immunity and fighting infections, bacterial and viral invasion. Regular consumption of vitamin C has also been tied to better management of life-threatening diseases like cancer. Here's a look at some of the top reasons why you must load up on vitamin C.

"There are many health benefits of Vitamin C. From combating stroke to healing wounds, Vitamin C also helps in the absorption of iron by the body. This is why it's suggested to pair foods full of Vitamin C with iron-rich foods," notes a nutritionist. 

- Vitamin C is loaded with antioxidants and polyphenols that act as natural agents that promote health and fight cell-damaging free radicals.

- Vitamin C is excellent for hair and skin health. Vitamin C helps in the production of collagen which reduces skin ageing and associated signs like wrinkles.

- Regular intake of vitamin C may stave off risk of hypertension, common cough and flu. It may also help in regulating stress hormones.

Vitamin C may also help boost metabolism and facilitate weight loss/management by metabolizing fat stores.

- Load up on vitamin C rich foods like kiwis, citrus fruits, greens, yellow peppers, papaya, strawberries, tomatoes and guavas among others.

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Two Drugs That Could Halt The Progression Of Neurodegenerative Diseases

Researchers have found two drugs already in various stages of use and human clinical trial that seem to prevent all neurodegenerative diseases in mice. Published in the journal Brain, the research could be a major breakthrough in preventing the devastating diseases from progressing in humans.

When brain cells are infected with a virus, the pathogen co-opts the cell to produce its own viral proteins, which begin to build up within the cell. In order to fight this and prevent the spread of the virus, the cell reacts by blocking all protein production. In many neurodegenerative diseases, a similar situation occurs, in which faulty proteins are over-produced in the brain cells and the brain reacts in a very similar way, but for much more prolonged periods.
Problems start to arise because the brain cells halt protein production for such a long period of time that the brains cells effectively starve themselves and start dying. When this spreads to neurons, it can then lead to the familiar symptoms of memory loss, movement impairment, and even death in severe types of neurodegenerative diseases.

In 2013, the same team of researchers found a compound that prevented the brain cells from overreacting and shutting down all protein production, which prevented the brain cells from dying. Yet there was a catch: the molecule also damaged the pancreas. And so they have since turned to other drugs to see if they can find others that achieve a similar result.

After screening over 1,000 different drugs already in existence, they came across two that seemed to have the desired effect. One of these, known as trazodone, is already used clinically to treat patients with depression, while the second, called DBM, is naturally found in small amounts in liquorice and is currently undergoing trials to see if it can effectively treat cancer.

The researchers first tested the drugs on mice that had a prion-related disease, and found that not only did it work in the same way that the previous one did in preventing brain cell death, the mice also showed improvement in disease-related behavior, while at the same time there was no observed impact on the pancreas. Following this, the drugs were then tested on mice that had other neurodegenerative diseases and they were found to improve their ability to perform memory tests.

This is promising news, as since the drugs have already been or are in the process of being tested on humans, it should make the process of proceeding to clinical trials much easier. While the researchers stress that the drugs are not a cure, they could prevent the disease progression, radically altering how we treat them. 

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