Easier detection of concussions!

According to a study some specific small molecules in blood plasma may be useful in determining whether someone has sustained a mild traumatic brain injury (mTBI), commonly known as a concussion.

Six specific small molecules from blood plasma were discovered in a group of college athletes who had been diagnosed with concussions. When these molecules were assessed, their combined presence accurately predicted whether teammates had sustained an mTBI or not.

This suggests that these small molecules, and possibly others, might be clinically relevant biomarkers of mTBI.

The same six biomarkers were then tested in a separate group of individuals, without and with mTBI, and the results replicated the athlete findings.

Although the results are encouraging, the authors reported limitations to their study and recommended additional investigations related to these and other mTBI biomarkers in blood that will further clarify their utility in clinical management.

“Such blood tests are important in determining not only whether someone has sustained a concussion, which is not currently an easy task, but may eventually prove useful in defining when injured individuals may be eligible to safely return to regular activities,” said  the paper’s first author.

Researchers are helping advance technologies and therapeutic approaches that may benefit all societies, but are directly relevant to their local populations.

The estimated 40 million individuals worldwide diagnosed with mTBI likely represent a gross underestimation of those actually sustaining such injuries.

Clinical practitioners require a relevant and reliable, minimally invasive, objective diagnostic test to determine high versus low probability of mTBI in a timely manner.

The author said there is a clear need to improve diagnostic capabilities, which could reduce under-reporting of mTBI and allow more appropriate care to be delivered to concussed individuals.

Although current technologies for defining the discovered small molecules in today’s publication lack the rapid, point-of-care platforms being developed for other measures, the study authors anticipated a growing technological momentum to develop such novel platforms resulting from this and similar investigations.

THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.                                                                                                                                                                                                        PS- THOSE INTERESTED IN RECIPES ARE FREE TO  VIEW MY BLOG-                                                                                           https://gseasyrecipes.blogspot.com/  

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ANTIBODIES THEMSELVES CAN CAUSE DISEASES

What happens when antibodies, a class of proteins generated by the immune system to neutralise foreign bacteria and viruses, attach themselves to the membrane protein of a human cell and try to destroy it?  Autoimmune diseases are the result.

Some brain diseases caused by antibodies come on quite quickly and can become severe quickly. But they can be treated, and the patients get better. Sometimes, the diseases burn itself out and the patient can even go off treatment.

Speaking about myasthenia gravis, marked by weakness of select muscles, the Dr. said, that in this disease, antibodies bind themselves to acetylcholine receptors, which lead to reduced signalling between nerves and muscles. Patients mobility problems, sometimes they can't keep their eyes open, in some cases, they can't swallow or drink. But with treatment, under patients' blood is removed through a centrifuge and put back minus the plasma containing the antibodies, there can be a remarkable improvement in just 2 days.

Sometimes, such diseases, appear and disappear quite suddenly. Why does this happen? While in some patients tumours, a preceding infection or a preceding allergic reaction is thought to have led to the disease, this may not always be the case. It may be just bad luck if you make one of these particular antibodies.

In India, probably 10 patients per million per year could be diagnosed with diseases caused by antibodies. The earlier the disease is diagnosed and treated, the better the chances for the patients recovery.

One interesting question researchers are now looking into is how frequently antibodies are the cause of common diseases such as epilepsy or dementia, the Dr. said.

ps- this is only for information, always consult you physician before having any particular food/ medication/exercise/other remedies.

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for info about knee replacement, you can view my blog-

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