ANTIBODIES THEMSELVES CAN CAUSE DISEASES
What happens when antibodies, a class of proteins generated by the immune system to neutralise foreign bacteria and viruses, attach themselves to the membrane protein of a human cell and try to destroy it? Autoimmune diseases are the result.
Some brain diseases caused by antibodies come on quite quickly and can become severe quickly. But they can be treated, and the patients get better. Sometimes, the diseases burn itself out and the patient can even go off treatment.
Speaking about myasthenia gravis, marked by weakness of select muscles, the Dr. said, that in this disease, antibodies bind themselves to acetylcholine receptors, which lead to reduced signalling between nerves and muscles. Patients mobility problems, sometimes they can't keep their eyes open, in some cases, they can't swallow or drink. But with treatment, under patients' blood is removed through a centrifuge and put back minus the plasma containing the antibodies, there can be a remarkable improvement in just 2 days.
Sometimes, such diseases, appear and disappear quite suddenly. Why does this happen? While in some patients tumours, a preceding infection or a preceding allergic reaction is thought to have led to the disease, this may not always be the case. It may be just bad luck if you make one of these particular antibodies.
In India, probably 10 patients per million per year could be diagnosed with diseases caused by antibodies. The earlier the disease is diagnosed and treated, the better the chances for the patients recovery.
One interesting question researchers are now looking into is how frequently antibodies are the cause of common diseases such as epilepsy or dementia, the Dr. said.
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Some brain diseases caused by antibodies come on quite quickly and can become severe quickly. But they can be treated, and the patients get better. Sometimes, the diseases burn itself out and the patient can even go off treatment.
Speaking about myasthenia gravis, marked by weakness of select muscles, the Dr. said, that in this disease, antibodies bind themselves to acetylcholine receptors, which lead to reduced signalling between nerves and muscles. Patients mobility problems, sometimes they can't keep their eyes open, in some cases, they can't swallow or drink. But with treatment, under patients' blood is removed through a centrifuge and put back minus the plasma containing the antibodies, there can be a remarkable improvement in just 2 days.
Sometimes, such diseases, appear and disappear quite suddenly. Why does this happen? While in some patients tumours, a preceding infection or a preceding allergic reaction is thought to have led to the disease, this may not always be the case. It may be just bad luck if you make one of these particular antibodies.
In India, probably 10 patients per million per year could be diagnosed with diseases caused by antibodies. The earlier the disease is diagnosed and treated, the better the chances for the patients recovery.
One interesting question researchers are now looking into is how frequently antibodies are the cause of common diseases such as epilepsy or dementia, the Dr. said.
ps- this is only for information, always consult you physician before having any particular food/ medication/exercise/other remedies.
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for info about knee replacement, you can view my blog-
http://Knee replacement-stick club.blogspot.com/
for crochet designs
http://My Crochet Creations.blogspot.com
Labels: antibodies, blood plasma, dementia, epilepsy
posted by G S Iyer at 9:33 PM
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