Sunday, September 18, 2022

HAY FEVER & ASTHMA: DEADLY COMBO

A study of school children conducted by University of Rochester Medical Center researchers has found that a majority of children with asthma also reported having allergic rhinitis, or hay fever. Symptoms of hay fever include runny nose, sneezing, congestion and sinus pressure, and can contribute to asthma. The HEALTH PIONEER shares details of the study.

The study, led by Jessica Stern, an assistant professor in the department of Pediatrics and division of Pediatric Allergy and Immunology, found that children with both asthma and hay fever had worse asthma outcomes. Not only this, half of children diagnosed with both asthma and hay fever were not receiving proper care and medication for their condition

This study reviewed data from three NIH-funded trials (led by Jill Halterman, professor in the department of Pediatrics) of 1,029 Rochester school children with asthma. The primary goal of the trials was to evaluate whether providing children with preventive asthma medications in school would improve their asthma symptoms. While most children participating in these trials had improved asthma symptoms when they received their medications, a subgroup of children did not improve. This prompted the researchers to look at other health concerns that might have prevented the children from having a full treatment response.

“Through our study, we found that many of the children who did not report improved symptoms had allergic rhinitis in addition to asthma, and these children had more asthma symptoms, used their rescue medication more, and missed more school days compared to those without allergic rhinitis,” said Stern.

Importantly, less than half of the children with hay fever were receiving proper treatment for their symptoms, including nasal sprays and recommended anti-histamines; nor had they been seen by asthma or allergy specialists.

“This is critical because it highlights gaps in care and needed treatments, which may contribute to the disparities in asthma outcomes that we see in children who primarily identify as Black or Latino, or are from low resourced communities,” said Stern. “These findings also encourage a focus on contributing environmental factors and the social determinants of health for these children. The burden of allergic disease is often under-recognized and under-treated in historically marginalized populations, and we have an opportunity and obligation to address this to improve outcomes.”

Dr. Stern will be continuing this work to understand the multiple influences in a child’s life that impact their asthma. She has grant funding from the Robert A. Winn Diversity in Clinical Trials Career Development Award, NHLBI, and the URMC Quality Institute.

 “We are working to create a comprehensive, multi-disciplinary approach to overcome structural obstacles to equitable care for children with asthma. This will involve collaboration with caregivers and patients to plan systems of care that work for them. We understand that families are the experts, and we have to listen to what they think,” said Stern.

 

Overview of HAY FEVER

Hay fever, also called allergic rhinitis, causes cold-like symptoms. These may include a runny nose, itchy eyes, congestion, sneezing and sinus pressure. But unlike a cold, hay fever isn't caused by a virus. Hay fever is caused by an allergic response to a harmless outdoor or indoor substance the body identifies as harmful (allergen).

Common allergens that can trigger hay fever symptoms include pollen and dust mites. Tiny flecks of skin shed by cats, dogs, and other animals with fur or feathers (pet dander) also can be allergens.

Besides making you miserable, hay fever can affect how well you perform at work or school and can generally interfere with your life. But you don't have to put up with annoying symptoms. You can learn to avoid triggers and find the right treatment.

 

This is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.   

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Monday, April 27, 2020

Atypical presentation of COVID-19 in young infants

As of April 27, 2020, more than two million people worldwide have been diagnosed with coronavirus disease 2019 (COVID-19), with Europe being one of the current major clusters of the pandemic.
Despite an absence of evidence, children have been targeted as a potential source of children-to-adult virus dissemination, and schools have been closed in most countries. However, findings seem to indicate a lower susceptibility of children to COVID-19 and low contagiousness.


Within 7 days of imposed population quarantine in France (initiated on March 17, 2020), we observed an increase in number of young infants with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.


This is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.     

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In our paediatric hospital, patients presenting with fever or respiratory symptoms, or both, and requiring admission to hospital are admitted to a dedicated SARS-CoV-2 infection unit. During the first week of quarantine, 14 infants younger than 3 months were admitted to this unit, and five of these young infants were diagnosed with COVID-19 on the basis of nasopharyngeal swabs positive for SARS-CoV-2. Their clinical presentations differed from those reported in articles about children with COVID-19.which present little data from younger infants.
 

The five infants with COVID-19 were boys. They had been healthy, but were admitted with poorly tolerated and isolated fever. None of the boys received non-steroidal anti-inflammatory drugs before admission, they had no respiratory symptoms before or during hospitalisation (in contrast with published data5), and they did not need intensive care.

Four of the boys showed neurological symptoms at admission, such as axial hypotonia or drowsiness and moaning sounds, or both, which prompted us to do lumbar punctures. Cerebrospinal fluid samples were normal and tested negative for SARS-CoV-2 by RT-PCR. The infants received no drugs other than acetaminophen. Their clinical course was rapidly favourable, which allowed hospital discharge 1–3 days after admission. A dedicated paediatrician supervised the follow-up, which consisted of a daily phone call using a standardised questionnaire for 2 weeks.


Here we describe our experience of COVID-19 in five young infants. In the pandemic context, infants younger than 3 months with isolated fever should be tested for SARS-CoV-2. Although infants might initially present signs of severe infection, our experience is that the youngest children tolerate and rapidly improve from COVID-19, in contrast to adults admitted to hospital with COVID-19. However, because little is known about SARS-CoV-2 infection in infants.


A close monitoring is required for at least 2 weeks after the diagnosis. All of the infants' parents showed mild signs of viral infection (ie, rhinitis, or cough or fever, or both, for <1 be="" br="" could="" covid-19.="" related="" to="" undiagnosed="" week="" which="">We declare no competing interests.

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