Cancer Treatment with NK Cells

Natural Killer Cells (NK Cells) are lymphocytes in the same family as T and B cells, coming from a common progenitor. However, as cells of the innate immune system, NK cells are classified as group I Innate Lymphocytes (ILCs) and respond quickly to a wide variety of pathological challenges. NK cells are best known for killing virally infected cells, and detecting and controlling early signs of cancer. As well as protecting against disease, specialized NK cells are also found in the placenta and may play an important role in pregnancy. 

NK cells were first noticed for their ability to kill tumour cells without any priming or prior activation (in contrast to cytotoxic T cells, which need priming by antigen presenting cells). They are named for this ‘natural’ killing. Additionally, NK cells secrete cytokines such as IFNγ and TNFα, which act on other immune cells like Macrophage and Dendritic cells to enhance the immune response.

How Do NK Cells Target Cancer Cells

While on patrol NK cells constantly contact other cells. Whether or not the NK cell kills these cells depends on a balance of signals from activating receptors and inhibitory receptors on the NK cell surface. Activating receptors recognise molecules that are expressed on the surface of cancer cells and infected cells, and ‘switch on’ the NK cell. Inhibitory receptors act as a check on NK cell killing. 

Most normal healthy cells express MHC I receptors which mark these cells as ‘self’. Inhibitory receptors on the surface of the NK cell recognise cognate MHC I, and this ‘switches off’ the NK cell, preventing it from killing.

Cancer cells and infected cells often lose their MHC I, leaving them vulnerable to NK cell killing. Once the decision is made to kill, the NK cell releases cytotoxic granules containing perforin and granzymes, which leads to lysis of the target cell.

NK21 – NK Cells for Cancer

At ImmuneCells21 we produce the NK21 – Natural Killer Cells for Cancer. The protocol we have developed produces 2 infusions of cytotoxic killer cells per blood collection (100ml). The NK cells are culture and released for therapeutic use on day 18 & day 21. In a full cancer treatment program we will perform 3 blood collections (weekly) & NK cultures, giving a total of 6 cytotoxic killer cell infusions on days: 

THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.                                    PS- THOSE INTERESTED IN RECIPES ARE FREE TO  VIEW MY BLOG-                                                                                           https://gseasyrecipes.blogspot.com/                                                                                                                                                FOR INFO ABOUT KNEE REPLACEMENT, YOU CAN VIEW MY BLOG-                                                                       https:// kneereplacement-stickclub.blogspot.com/                                                                                                                     FOR CROCHET DESIGNS                                                                                                   

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All About Your White Blood Cells

White blood cells (WBCs) form the part of your immune system which is responsible for fighting infection and defending the body against other foreign materials. Various kinds of WBCs are involved in recognizing intruders, destroying harmful bacteria, and synthesizing antibodies to defend your body from future exposure to nasty bacteria and viruses.

Types of White Blood Cells
There are 5 main types of white blood cells, which include:
Neutrophils - Around half of your white blood cells are neutrophils. These cells are normally the first to appear in response to threats. As first responders, they also send out messages which alert other immune cells to respond. Your body produces close to 100 billion neutrophils each day, and once they are released from the bone marrow live for only 8 hours.
Lymphocytes (B lymphocytes and T lymphocytes) - There are 2 types of lymphocytes, with T cells being responsible for directly killing infections, while B cells are responsible for humoral immunity. They create the antibodies which "remember" a threat and stand ready in case your body should ever be exposed to them again.

Monocytes - Monocytes are practically your immune system's garbage trucks. Around 5 percent of your white blood cells are monocytes, and their most essential function is to move into tissue and clean up any dead cells.
Eosinophils - Eosinophils play a critical role when it comes to fighting off bacteria, and they are also very important in responding to parasitic infections. They are also notorious for their role in producing allergy symptoms when they essentially believe that something harmless (such as pollen) is an invader. These are only around 1% of the white blood cells in your body but are highly concentrated in the digestive tract.

Basophils - Basophils also make up only 1% of your body's white blood cells, and are important in mounting a non-specific immune response to infections. Basophils are best known for their role in asthma, since their stimulation may result in the inflammation and bronchoconstriction of your airways.

Conditions Involving High White Blood Cell Levels

There are a number of reasons why a person's white blood cell count may be too high, including:

• Infections
• Stress
• Exercise
• Certain cancers
• Inflammation
• Autoimmune disorders
• Trauma ranging from emotional stress to fractures
• Pregnancy
• Asthma
• Allergies 

Conditions With Low White Blood Cell Levels

There are also quite a few reasons as to why white blood cell levels could be too low, including:

• Severe infections
• Bone marrow damage
• Aplastic anemia
• Drug or chemical-related damage to your bone marrow
• Autoimmune diseases such as lupus
• Splenic sequestration

Symptoms of a Low White Blood Count

A low white blood cell count may be accompanied by quite a number of symptoms. These may include:

• Blood in the stools
• Fever
• Cough
• Pain or frequency of urination
• Diarrhea
• Redness, swelling, or warmth in a region of infection

THIS IS ONLY FOR INFORMATION, ALWAYS CONSULT YOU PHYSICIAN BEFORE HAVING ANY PARTICULAR FOOD/ MEDICATION/EXERCISE/OTHER REMEDIES.                                                                                                                                                                                                                                                                                        PS- THOSE INTERESTED IN RECIPES ARE FREE TO  VIEW MY BLOG-                                                                                           https://gseasyrecipes.blogspot.com/                                                                                                                                                                             FOR INFO ABOUT KNEE REPLACEMENT, YOU CAN VIEW MY BLOG-                                                                                                                             https:// kneereplacement-stickclub.blogspot.com/                                                                                       FOR CROCHET DESIGNS                                                                                                                                                                                                                                 https://gscrochetdesigns.blogspot.com