Wednesday, February 12, 2020

5 Neuroscience Based Ways to Clear Your Mind

As an ultra-endurance athlete, I’ve competed in the Badwater Ultramarathon a few times. Some call Badwater the “world’s toughest footrace” because it's a 135-mile non-stop run from the bottom of Death Valley to Mt. Whitney—in the middle of July, when temperatures can reach 130 degrees.

The physical discomfort of running five marathons back-to-back through Death Valley in the middle of July requires more psychological finesse than it does aerobic endurance. Succeeding in sports is always going to rely on mastering your mindset and explanatory styles. As Yogi Berra said, “Baseball is 90 percent mental; the other half is physical.”

One of the most important skills I've learned as an ultra-endurance athlete is how to clear my mind of unwanted thoughts. When your feet are covered in blisters, the pavement is hot enough to fry an egg, and you still have three marathons to run, you learn quickly how to pull any tricks from your psychological toolbox that will help you reach the finish line.

When every alarm in your body and brain is sounding a red alert telling you to stop, how does someone push through and keep on going? When it comes to clearing your mind of unwanted thoughts, taking a multi-pronged approach that gives the situation what it needs has always worked for me in sports, and I think it will work for you, too, in sport and in life.

For this post, I’ve compiled a top-five list of mental tricks I learned as an athlete to clear my mind of pain, negative thinking, anxiety, rumination, and self-sabotage. I’ve paired the lessons I learned through life experience with the latest neuroscientific evidence. I also included some images that capture the essence of each point, as a picture really is worth a thousand words.


1. Distraction

American editor and publisher Elbert Hubbard,once said, “Life without absorbing occupation is hell—joy consists in forgetting life.” Neuroscientists at Brown University recently confirmed that the key to “optimal inattention” lies in occupying your mind with something else through distraction.

The mind can only really think of one thing at a time. When you concentrate your attention on one thing, you inevitably engage the parallel act of purposefully ignoring other things. In a 2015 study, “Attention Drives Synchronization of Alpha and Beta Rhythms between Right Inferior Frontal and Primary Sensory Neocortex,” published in the Journal of Neuroscience, the researchers at Brown were able to identify how the brain achieves "optimal inattention" by changing the synchronization of brainwaves between different brain regions. The researchers hope that by harnessing the “power to ignore," people with chronic pain will have new cognitive tools for reducing their pain.


For this study, participants were told that they would feel a brief tap on the left middle finger or the left big toe. In some cases, they were then told to report only stimuli felt on the foot and to disregard what they might feel on their hand. In other cases, they were told to attend to or report sensations only in the hand and to ignore those in the foot.

The researchers found significant patterns of synchrony between various regions which showed that the mind could direct attention to either the hand or the foot, but not both at the same time.

If you ever find yourself obsessing or ruminating about a thought, remember that distraction is a highly effective way to shift the synchronization of your brainwaves and gives you the "power to ignore" on demand. 


2. MindfulnessThe Brown study's co-senior author, Catherine Kerr, is an assistant professor of family medicine in the Alpert Medical School. Her team has also found that people can learn how to manipulate their alpha rhythms in the somatosensory cortex as they switch their attentional focus though mindfulness training.

The results of their latest research expand our understanding of how mindfulness might possibly operate using the mechanism of redirecting attention via control of alpha rhythms in the brain, which can help people ignore depressive thoughts. In a press release, she said:

This is part of a really cool effort ... to see if you can take pretty high-level cognitive questions, find the relevant areas in the brain, and then figure out how to put that in a context with the underlying neurophysiology, at the level of computational models and animal models. We're linking different ways of looking at the brain that don't usually come into dialogue with one another.


In another recent study from Lund University in Sweden, researchers led by Jan Sundquist found that mindfulness treatment can be as effective as individual cognitive behavioral therapy (CBT) in patients with depression and anxiety.


3. Suppression
Nietzsche said, “The existence of forgetting has never been proved: We only know that some things do not come to our mind when we want them to.” It turns out that modern brain imaging technology has allowed neuroscientists at the University of Cambridge to identify two opposite ways in which the brain forgets unwanted memories.

In a 2012 study, “Opposing Mechanisms Support the Voluntary Forgetting of Unwanted Memories,” published in the journal Neuron, the researchers’ findings help explain how individuals can cope with negative or traumatic experiences, and could lead to the development of treatments to improve disorders of memory control.

In a press release, lead author Roland Benoit, then a postdoctoral fellow at Harvard University, said, "This study is the first demonstration of two distinct mechanisms that cause such forgetting: one by shutting down the remembering system, and the other by facilitating the remembering system to occupy awareness with a substitute memory."  


During memory suppression, a brain structure called dorsolateral prefrontal cortex inhibited activity in the hippocampus, a region critical for recalling past events.

"A better understanding of these mechanisms and how they break down may ultimately help understanding disorders that are characterized by a deficient regulation of memories, such as post-traumatic stress disorder," Benoit said. "Knowing that distinct processes contribute to forgetting may be helpful, because people may naturally be better at one approach or the other."


4. Substitution

Although the strategies of using suppression and substitution were found to be equally effective at voluntarily forgetting unwanted memories, the researchers at Cambridge found that they activated very distinct neural circuits.

If suppression doesn't work, you might want to put on your "rose-tinted glasses" and try substitution, by using your imagination to pretend you're in a different place or experiencing something else.

The Cambridge researchers found that memory substitution was supported by caudal prefrontal cortex and midventrolateral prefrontal cortex. These are two regions typically involved in bringing specific memories into awareness in the presence of distracting memories.

The next time you need to clear your mind, remember that you can forget unwanted memories by either suppressing them or substituting them with more desirable ones, and that each of these tactics engages distinct neural pathways.


5. Meditation

Rebecca Erwin Wells, M.D.,and Fadel Zeidan, Ph.D. at Wake Forest Baptist Health are investigating the power of meditation as a therapy to reduce pain and everyday anxiety in healthy individuals with no previous meditation experience.

When Wells was a varsity rower at the University of North Carolina, her coach had all the members of the team take a yoga and meditation class. The experience had a huge impact. In a press release Wells recalled the experience:

My teammates and I noticed that yoga and meditation improved our flexibility and focus, but also made us feel better, not just when we were rowing but in our everyday lives. I wondered if yoga and meditation really have scientific benefits, especially if they have specific effects on the brain, and if so, how that works.

"We're coming to recognize that meditation changes people's brains," said Wells, now an assistant professor of neurology at Wake Forest Baptist Medical Center. "And we're just beginning to gain understanding of what those changes mean and how they might benefit the meditator."

In the first study, her team found that just eight weeks of meditation significantly improved functional connectivity in the brain's network that is active during introspective thought such as retrieving memories. They also observed trends of less atrophy in the hippocampus.

Zeiden is exploring the specific brain mechanisms that influence meditation's ability to reduce perceptions of pain and the experience of anxiety. In Zeidan's pain study, participants were asked to grade the pain caused by a device that heated a small area of their skin to 120 degrees. Participants who rated the pain they felt while they meditated reported the pain as 40 percent less intense and 57 percent less unpleasant than when they simply rested with their eyes closed.

The brain imaging performed during this experiment showed decreased neural activity in the area of the brain involved in feeling the location and intensity of pain and increased activity in brain regions associated with attention and the ability to regulate emotions.

In Zeiden's anxiety-related research, the subjects reported decreases in everyday anxiety by as much as 39 percent after practicing meditation. The scans of their brains while meditating showed increased activity in areas of the cortex associated with regulating thinking, emotions, and worrying. In a press release Zeiden said:

In these studies we've been able to get a better sense of the brain regions associated with reducing pain and anxiety during meditation. Basically, by having people meditate while their brains are being scanned we've been able to objectively verify what people like Buddhist monks have been reporting about meditation for thousands of years.

"Our research shows that meditation produces robust effects in behavior and in the brain and may provide an effective way for people to substantially reduce their pain," Zeidan concluded. "What we have to do now is continue to find out exactly how it works and what it involves."


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Sunday, November 05, 2017

Scientists identified chemicals in brain that helps to avoid unwanted thoughts

Scientists have identified a key chemical in the brain that allows us to suppress unpleasant memories, a finding that may pave the way for treating patients of post-traumatic stress disorder (PTSD), depression or schizophrenia who experience persistent intrusive thoughts.

"Our ability to control our thoughts is fundamental to our wellbeing," said a scientist.

"When this capacity breaks down, it causes some of the most debilitating symptoms of psychiatric diseases: intrusive memories, images, hallucinations, ruminations, and pathological and persistent worries," he said .

"These are all key symptoms of mental illnesses such as PTSD, schizophrenia, depression, and anxiety," he said.

The scientist likens our ability to intervene and stop ourselves retrieving particular memories and thoughts to stopping a physical action.

A region at the front of the brain known as the prefrontal cortex is known to play a key role in controlling our actions and has more recently been shown to play a similarly important role in stopping our thoughts.

The prefrontal cortex acts as a master regulator, controlling other brain regions - the motor cortex for actions and the hippocampus for memories.

In the study published, scientists used a task known as the 'Think/No-Think' procedure to identify a significant new brain process that enables the prefrontal cortex to successfully inhibit our thoughts.

In the task, participants learn to associate a series of words with a paired, but otherwise unconnected, word, for example ordeal/roach and moss/north.

In the next stage, they were asked to recall the associated word if the cue is green or to suppress it if the cue is red; in other words, when shown 'ordeal' in red, they were asked to stare at the word but to stop themselves thinking about the associated thought 'roach'.

Using a combination of functional magnetic resonance imaging (fMRI) and magnetic resonance spectroscopy, the researchers were able to observe what was happening within key regions of the brain as the participants tried to inhibit their thoughts.

Researchers showed that the ability to inhibit unwanted thoughts relies on a neurotransmitter - a chemical within the brain that allows messages to pass between nerve cells – known as GABA.
GABA is the main 'inhibitory' neurotransmitter in the brain, and its release by one nerve cell can suppress activity in other cells to which it is connected.

Researchers discovered that GABA concentrations within the hippocampus - a key area of the brain involved in memory - predict people's ability to block the retrieval process and prevent thoughts and memories from returning.

The scientist believes the finding could offer a new approach to tackling intrusive thoughts in these disorders.

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