The reason behind drastic memory loss in Alzheimer’s patients

An alteration in a gene may speed up the loss of memory and thinking skills in people who are already at the risk of Alzheimer's disease, according to a study. 

According to researchers, people with Alzheimer’s risk, who have the gene mutation called the BDNF Val66Met allele, or the Met allele may have a more rapid decline of memory and thinking skills. Further, people with the gene mutation, who also had more beta-amyloid — a sticky protein that can build up into plaques found in the brains of people with Alzheimer’s disease — had an even steeper rate of decline. “Because this gene can be detected before the symptoms of Alzheimer’s start, and because this presymptomatic phase is thought to be a critical period for treatments that could delay or prevent the disease, it could be a great target for early treatments,” said Ozioma Okonkwo, from the University of Wisconsin in Madison, US. 

For the study, published in the journal Neurology, the team followed 1,023 people with an average age of 55 for up to 13 years who were at risk of Alzheimer’s but were still healthy during the onset. On tests of verbal learning and memory, those with no gene mutation improved by 0.002 units per year, while the scores of people with the mutation declined by 0.021 units per year. This could be because, “when there is no mutation, it is possible the BDNF gene and the protein it produces are better able to be protective, thereby preserving memory and thinking skills”, Okonkwo said. 

this is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.   
https://gscrochetdesigns.blogspot.com. one can see my crochet creations 
https://gseasyrecipes.blogspot.com. feel free to view for easy, simple and healthy recipes    
https://kneereplacement-stickclub.blogspot.com. for info on knee replacement   

'Pink noise' can help old people sleep their way to better memory

You may want to listen to pink noise, described as a waterfall-like sound, during bedtime as a recent study has suggested that doing so can improve memory.
 
The study is published in Frontiers in Human Neuroscience. Gentle sound stimulation synchronized to the rhythm of brain waves significantly enhanced deep sleep in older adults and improved their ability to recall words, reported a new Northwestern Medicine study.

"This is an innovative, simple and safe non-medication approach that may help improve brain health," said senior author Phyllis Zee. "This is a potential tool for enhancing memory in older populations and attenuating normal age-related memory decline."
In the study, 13 participants 60 and older received one night of acoustic stimulation and one night of sham stimulation. The sham stimulation procedure was identical to the acoustic one, but participants did not hear any noise during sleep. For both the sham and acoustic stimulation sessions, the individuals took a memory test at night and again the next morning. Recall ability after the sham stimulation generally improved on the morning test by a few percent. However, the average improvement was three times larger after pink-noise stimulation.

The degree of slow wave sleep enhancement was related to the degree of memory improvement, suggesting slow wave sleep remains important for memory, even in old age.

Although the Northwestern scientists have not yet studied the effect of repeated nights of stimulation, this method could be a viable intervention for longer-term use in the home, Zee said.

 this is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.
https://gscrochetdesigns.blogspot.com. one can see my crochet creations
https://gseasyrecipes.blogspot.com. feel free to view for easy, simple and healthy recipes 
https://kneereplacement-stickclub.blogspot.com. for info on knee replacement