Thursday, March 03, 2022

Menstrual pain could be endometriosis; affects 1 in 10 females in child-bearing years in S'pore

For around a decade during her teenage years, Member of Parliament Carrie Tan suffered severe menstrual cramps every month, where the pain was so intense that she had to lie down to wait for it to subside.

The agony was so bad that when she was in her late 20s, there were two consecutive months she blacked out when her period came. On the second occasion, she broke out in cold sweat, blacked out, woke up feeling afraid and made a trip to the emergency department of a hospital.

"I was put on drips, given painkillers and again sent home. No one told me why I was having so much pain," the 39-year-old MP for Nee Soon GRC said in a virtual media briefing on Wednesday (March 2), a day before the start of Endometriosis Awareness Week.

She later discovered that she suffered from endometriosis, a chronic condition where tissues resembling the lining of the womb grow in other organs such as the ovaries, bowels and even the lungs and nose.

This may result in pain in various parts of the body, including while urinating and during sex, and increased menstrual discomfort.

Ms Tan's condition is common here, where about one in 10 females in child-bearing years suffer from it. Endometriosis is a disorder that is dependent on the female hormone estrogen, hence, the condition tends to regress after menopause. Estrogen levels decline during menopause.

Dr Ma Li, a consultant in the department of obstetrics and gynaecology at the National University Hospital (NUH), said: “Endometriosis is a systematic disease  that can affect the whole body and other organs including uterus, ovaries, vagina and rectum. Early treatment will help these women with their overall and reproductive health.”

Some 30 per cent to 50 per cent of women with endometriosis encounter challenges conceiving, said Dr Celene Hui, a consultant in the minimally invasive surgery unit, division of obstetrics and gynaecology at KK Women's and Children's Hospital.

Endometriosis can result in inflammation and scarring, damaged fallopian tubes, impaired embryo implantation, poorer egg quality and decreased egg supply or ovarian reserve, she added.

These painful periods can also result in emotional distress, affecting work and quality of life.

"Most of the time, women of the reproductive age group attend our clinics because they are trying to start a family. The child-bearing potential declines significantly with increasing age. I urge women with symptoms of endometriosis to come forward earlier, so that their pain can be better managed and their fertility may be preserved and protected," Dr Hui said.

There is currently no non-invasive, reliable method for diagnosing endometriosis, so the condition's true prevalence is unknown. Although surgery still remains the gold standard for definitive diagnosis, there is a shift towards diagnosing endometriosis based on symptoms and investigations, allowing doctors to start treatment earlier rather than later. 

Dr Hui added that there is a 6.7 year delay between symptom onset and diagnosis, as the lack of awareness of this condition, stigma around menstruation and lack of specific symptoms increase the difficulty of diagnosis.

This condition is more common among Asians compared with Caucasians, and more prevalent among women with a lower body mass index. Those with a short menstrual cycle length or experience obstruction of menstrual flow are also likely to experience higher risk.

To help women diagnose this condition, an online questionnaire that is available in four languages can be done.

"The higher the score, the more they should see a doctor to seek advice. We are still in a society where everybody thinks it is normal to have some menstrual pain. But when the pain becomes so severe that it's affecting your job, your quality of life, it can't be normal any more," Dr Anthony Siow, medical director at ASC Clinic for Women in Gleneagles Medical Centre, said.

Based on the endometriosis questionnaire carried out from March 2021 to February 2022 involving 2,522 women in Singapore, it was found that 55 per cent suffer from symptoms that may suggest possible endometriosis or other gynaecological conditions that warrant a visit to a gynaecologist.

The questionnaire – created by doctors from NUH, Singapore General Hospital and KKH – also found that more than half of the participants are on regular medicines or supplements to control their pain.

Medical therapy can provide effective pain relief in 60 per cent of women here. This can be in the form of hormonal therapy with the progestin-only pills or the combined hormonal contraceptive pill, the hormonal intrauterine device or medications to induce a menopausal state.

Surgery can also be performed through keyhole incisions.

For Ms Tan, she changed her diet, consuming more “warming foods” such as ginger tea a few days before her period and cutting cold drinks out as much as possible. 

She still suffers from period pain, but it does not happen every month and is manageable now.

On how to raise awareness and reduce the stigma around periods, she stressed that it is important to encourage conversations.

There are ground-up initiatives, such as a campaign called E for Endometriosis that is actively going around spreading awareness of the condition, Ms Tan said. 

The campaign was started by Ms Namira Mohamad, who began experiencing painful menstrual cramps right from her first period at age 11. She is a stage four endometriosis patient.

“If we can make conversations around periods and menstrual pains more commonplace and easier to talk about, then it is easier for women to share their pain and experience... then those who have more awareness can share the knowledge and encourage others to step forward to see their GPs,” Ms Tan added.

On advocacy to employers, efforts such as opening up conversations at the workplace, holding health talks and educating human resource departments about this condition will be useful.

"So that women don't feel shy to talk about it and to seek help," Ms Tan said.


 

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Wednesday, March 25, 2020

Novel method for measuring quality of life for people on autism spectrum

Researchers show that a set of simple questionnaires can help clinicians and families better evaluate the quality of life of people diagnosed with autism spectrum disorder (ASD). This newly-developed tool is designed for children, adolescents, and adults on the autism spectrum, and the findings show where clinicians can learn more about how to support the needs of autistic individuals by directly asking them these critical questions.

The findings of the study led by researchers at Children’s Hospital of Philadelphia (CHOP) was published the journal Autism Research. While clinical researchers often focus on measuring diagnostic criteria or behavioural impairments, autistic self-advocates, family members, and community organizations have long called for a greater emphasis on measuring specific and practical areas that, if properly addressed, could then help people on the autism spectrum achieve a better quality of life.


Several methods on how to accomplish this have been proposed, but they have not necessarily addressed topics covering a person’s entire lifespan or had sufficient data on women and girls.

“Individual studies have examined the specific quality of life measurements for people with autism, but we believed there was an opportunity to create an approach that could measure the quality of life across multiple areas, in a way that can grow throughout their lifetime as needs change,” said Laura Graham Holmes, PhD, a postdoctoral researcher at the A.J. Drexel Autism Institute at Drexel University who led the research while she was a postdoctoral fellow at the CHOP Center for Autism Research.

“We wanted to be sure this tool encompassed a variety of domains, including physical and mental health, relationships, and subjective well-being, so we could begin to understand on a more nuanced level the struggles and successes that autistic people experience throughout their lives.”

The study team developed and tested an autism-specific lifespan quality of life measurement tool, using the National Institutes of Health Parent-Reported Outcomes Measurement Information System (PROMIS®) as its foundation. The new tool is named the PROMIS Autism Battery – Lifespan (PAB-L).


After reviewing each area and receiving feedback from autistic people and their families as well as autism experts, the tool was administered for autistic children ages 5-13 (reported through parent proxy), adolescents ages 14-17 (parent proxy and/or self-reported), and adults ages 18-65 (self-reported) and then results were compared with the general population. A total of 912 participants completed the tool’s surveys online. The study measured feasibility, and participants reported that the survey was easy to understand, covered important topics, and may even change the way an individual or parent manages their autism support programs or clinical care based on the results.

While some individuals reported strengths, on average, people of all ages on the autism spectrum reported greater challenges and lower quality of life compared with their peers without an autism diagnosis. In particular, they reported lower life satisfaction, less social support and more social isolation, were more likely to exhibit emotional distress through symptoms like anger and anxiety and were more likely to have sleep problems.

Women and teenaged girls on the autism spectrum reported higher levels of anxiety and sleep problems than their male counterparts. As this is the first study to use this tool, more work is needed. However, these measurements give researchers an important starting point.

“This study demonstrated that assessing the quality of life among patients of different ages and genders is possible and that it’s meaningful,” said Judith S. Miller, PhD, a psychologist in the Department of Child and Adolescent Psychiatry and Behavioral Sciences, a senior scientist and training director in the Center for Autism Research at CHOP and senior author of the study.

“We believe that these findings provide an important foundation to answer some very important questions about how to support the quality of life for people with autism, including those who have been historically underrepresented in clinical research.


This is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.     

https://gscrochetdesigns.blogspot.com. one can see my crochet creations  
https://gseasyrecipes.blogspot.com. feel free to view for easy, simple and healthy recipes    
https://kneereplacement-stickclub.blogspot.com. for info on knee replacement

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