Monday, March 21, 2022

The power of slow therapy, revealed in two pioneering memoirs

You’ve probably heard of cognitive behavioural therapy, a form of psychotherapy that lends itself to research trials and is deliverable in a short, efficient, standardised form. Many clinical psychologists today regard this kind of ‘evidence-based psychotherapy’ as the future. Some do so cautiously, some posturing hubristically. Others are sceptical, either for valid reasons or out of closed-mindedness. I’m an agnostic on this matter, more interested in how evidence-based approaches might address their shortcomings and reach their potential.

To this end, an important first step I suggest is to pay closer attention to our therapy clients and find better ways to listen to, and respond to, their feedback. Encouraging our own clients to write freely about their experiences in therapy would help, but I find that there are also rich insights to be gleaned from published memoirs. They can remind us of the value of slower ways of doing therapy that are supposedly passé.

Two extraordinary, trailblazing examples of the genre by Lucy Freeman (1916-2004) stand out. In 1940, Freeman was one of the few women hired at The New York Times, becoming the first person to cover mental health news; indeed, she invented this as a legitimate beat for a reporter. A prolific author of more than 70 books, her two therapy memoirs provide the first detailed, authentic account of experiencing psychoanalysis from the client’s point of view.

The first, Fight Against Fears (1951), sold more than a million copies. The story begins with Freeman’s suffering, which leads her to sign on to psychoanalysis as an adventure, not quite knowing what to expect. Initially, she insists that she did not recall much about her childhood and that it had been happy. She is encouraged to provide more detail by JH (her analyst) and begins to realise that she often felt lonely and had an acrimonious relationship with her mother and an idealising relationship to her father. I imagined that a psychoanalyst would thrill to make an Oedipal interpretation. Instead, JH focuses on the absence of love and nurturing in Freeman’s family of origin, sins of omission more than commission, in his words. This surprised me, and it prompted me to feel a concern that we – many contemporary psychologists and society at large – have become too comfortable accepting a distorted, caricatured image of psychoanalysis.

Freeman responds well to her analyst’s effort to explore the past, realising, for instance, that it was mainly when sick that she received attention at home. Another painful memory comes to light: proudly showing her mother a poem she had written, only to have her mother react by doubting that she was the author. The portrait that emerges is of an invalidating environment, characterised by explosions of hostility. As the analysis deepens over time, Freeman and her therapist dwell on the legacy of fear that haunted Freeman and interfered with her being able to connect with others.

There are also cringeworthy moments in the memoir, such as JH’s apparent sexism (he implies that becoming a journalist occurred at the expense of Freeman’s identity as a wife and mother); some predictable homophobia; and a strange moment of unabashed advocacy of corporal punishment. Freeman never learns much about JH because of his neutral stance, but she does glimpse his lack of enthusiasm about diagnosis and his scepticism about research, which I saw as unfortunate manifestations of psychoanalytic smugness. At this point I found my initial positive impression somewhat eclipsed by troubled, disheartened feelings.

Ultimately, though, Freeman depicts JH as kind, attentive and helpful, and there are potential lessons here for how psychotherapy is practised today, whatever school a therapist comes from. Indeed, JH does not fit the image of a psychoanalyst that I conjure from those heady days of the field: he is not dogmatic or domineering, and he does not engage in or endorse parent-blaming. Rather, he helps Freeman to become less self-indulgent and more empathic in understanding how her parents’ own history played out in the way that they parented her. Moreover, JH makes room for her to take the lead in exploring her own mind. This particularly perked my attention, as it clearly anticipates contemporary psychology’s focus on the quality of the therapist-client relationship as being a key component of effective therapy. This analyst had his faults, but he was no guru and was persistently devoted to his client’s welfare.

How does Freeman characterise the benefits of psychoanalysis? Her sinusitis disappears, and she no longer whispers in a voice that others could not hear. But Freeman regards the analysis as transmutative on a deeper level, helping her to develop the capacity to think about feelings, value the integration of thinking and feeling, and become appropriately vigilant about the boundary between self and other. As a consequence, her siblings play a bigger role in her life, and she becomes closer to them. Freeman concludes her first memoir by affirming a string of ‘c’ words: compassion, control, conviction, calmness, compromise, and courage. In valuing the importance of learning flexible psychological skills over achieving static insights, I found Freeman’s description of her therapy startlingly contemporary. In fact, her understanding of the goals of psychotherapy resembles what we might now regard as improved ‘mentalisation’ or the ability to think about one’s own thinking and feelings.

In Freeman’s second memoir published decades later, The Beloved Prison (1989), she commences a new analysis with a female therapist, picking up the pieces after a disastrous marriage that occurred after her time with JH. She traces the unfolding of a profitable relationship with her new therapist – until the woman’s premature death. Freeman then embarks on a new treatment, but this third analyst behaves badly: she eats dinner in sessions, criticises Freeman’s clothes, and turns flagrantly unempathetic after Freeman goes through an abortion.

Her fourth and final psychoanalysis, with the therapist ‘DA’, turns out better. From the outset, there is what’s known as ‘positive transference’ (the projection of positive feelings from another relationship onto the therapist): DA is described as a young, handsome man who carries himself in a modest way. Over the course of this treatment, Freeman becomes more comfortable with intense emotions, fully experiencing the anger and anxiety that were identified earlier as issues by JH. She describes her evolution to bear rage against DA as well as her parents, which he responds to with enthusiasm. The trust that she accords to DA leads her to trust in and be more comfortable with herself. Freeman is able to escape the ‘beloved prison’ that was her life, but now she faces the challenge of leaving the prison of the couch as well.

Freeman became a passionate advocate for psychoanalysis and she deserves admiration for her valuable contribution to the field, all the more so in our era of evidence-based practice, in which one must strain to hear clients’ voices. Freeman offers us an astute glimpse into the convoluted path that therapy typically takes and she underscores how the relationship to the therapist is crucial to the experience, especially in establishing an environment in which the client can take the lead. Perhaps the most striking indication of her transformation is that she succeeded in writing such creative, self-revealing books.

Although Freeman’s faith in psychoanalysis has the zeal of a convert, she provides compelling testimony that forces us to reckon with why long-term work was necessary. But what do we make of the fact that Freeman’s first successful analysis is followed by a disastrous marriage, and that she continued to seek out multiple analyses to help her deal with her suffering? She addresses this by asserting that her fate would have been worse without all the analysis. She insists that psychoanalysis was ‘the best investment’ and that it bestowed a sense of abiding peace.

While awkward in spots, Freeman’s documentation of her analysis provides a reminder of a time when therapy could be exploratory without pre-established limits. Such an adventure might well be labelled as a luxury of a bygone era, but it is hard to deny the benefit of investing time and effort to gain as much self-understanding as possible. We live in an age where there is a plethora of treatments, and long-term therapy might not be the best choice for everyone. Yet, it is still the option that provides the greatest potential rewards. Let’s not kid ourselves: no serious work of art and no serious thinking support the notion that self-knowledge and character change follow a short, narrow, linear path. Reading Freeman in 2022 serves as a stark reminder about the diminution of expectations for mental health treatment in our own time.

My emotions fluctuated wildly while reading Freeman’s two memoirs, eluding easy identification, modulation or expression. Not only was I often surprised, I found myself quite envious of her opportunity to engage in therapy at a pace that was not at the mercy of practical constraints. Yet I also felt disappointed by my field’s failure to acknowledge her intrepid path. Indeed, it is impossible to read Freeman without recognising how much feminism has transformed the landscape of mental health and our culture at large. I was impressed that the process was so lively and unformulaic. What if we take seriously that setting goals in therapy from the beginning might interfere with the subsequent process of discovery? What if we were to construe false starts and mistaken directions as unavoidable, par for the course, and sometimes illuminating? What if we were determined to aim higher and not rest content with mere symptom relief? Here’s my challenge to the evidence-based crowd: you must take adequate precautions not to provide clients only with what you have to offer, at the expense of what they actually want.

And what about psychoanalysis? Today, it survives in humbler forms than Freeman experienced, but it continues to affirm a commitment to the vast unruliness of the mind, cultivating reflection on emotions in relation to past history, and persevering in the elusive search for well-being, as Freeman proclaimed many years ago. Her work lends strong support to the value of long-term therapy and the need to make room for what clients have to tell us about the work that we do.

 

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Tuesday, January 21, 2020

New Techniques Yield New Info on Alcohol Related Birth Defects

A collaborative research effort by scientists at the University of North Carolina School of Medicine, Duke University, and University College of London in the UK, sheds new light on alcohol-related birth defects.

The project, led by Kathleen K. Sulik, PhD, a professor in the Department of Cell and Developmental Biology and the Bowles Center for Alcohol Studies at UNC, could help enhance how doctors diagnose birth defects caused by alcohol exposure in the womb. The findings also illustrate how the precise timing of that exposure could determine the specific kinds of defects.

“We now know that maternal alcohol use is the leading known and preventable cause of birth defects and mental disability in the United States,” Sulik said. “Alcohol’s effects can cause a range of cognitive, developmental and behavioral problems that typically become evident during childhood, and last a lifetime.”

Fetal alcohol syndrome (FAS) is at the severe end of fetal alcohol spectrum disorders (FASD). First described in 1972, FAS is recognized by a specific pattern of facial features: small eyelid openings, a smooth ridge on the upper lip (absence of a central groove, or philtrum), and a thin upper lip border.

In its full-blown state, FAS affects roughly 1 in 750 live births in the U.S. And while clinicians typically look for those classical facial features in making a diagnosis, within the broader classification of FASD “adverse outcomes vary considerably and most individuals don’t exhibit the facial characteristics that currently define FAS,” said the study’s lead author Robert J. Lipinski, PhD, a postdoctoral scientist in Sulik’s lab. “This study could expand the base of diagnostic criteria used by clinicians who suspect problems caused by maternal alcohol use.”

In their animal-based studies, the Sulik lab team has collaborated with co-author G. Allan Johnson, PhD and his group at Duke University’s Center for In Vivo Microscopy. Johnson, professor of radiology and physics, has developed new imaging tools with spatial resolution up to a million times higher than clinical magnetic resonance imaging (MRI). These include small bore tools suitable for imaging fetal mice that are only 15 mm long.

To quantify facial shape from MRI data, the study team turned to co-author Peter Hammond, a professor of computational biology at UCL’s Institute of Child Health, in London. Hammond invented powerful new techniques for 3D shape analysis that have already proven successful in objectively defining facial shape changes in humans.

In the study, described in the August 22, 2012 issue of the online journal PLOS ONE, Lipinski and Sulik treated one group of mice with alcohol on their seventh day of pregnancy, a time corresponding to the third week of pregnancy in humans. A second group of mice was treated just 36 hours later, approximating the fourth week of human pregnancy. The amount of alcohol given was large, “high doses that most women wouldn’t achieve unless they were alcoholic and had a tolerance for alcohol,” Sulik said.

Near the end of pregnancy, the fetuses were then imaged at Duke University. These 3D data sets showed individual brain regions, as well as accurate and detailed facial surfaces, from which Hammond and research assistant and co-author Michael Suttie performed shape analyses.

The team found that the earlier alcohol exposure time elicited the classic FAS facial features, including characteristic abnormalities of the upper lip and eyes. What they observed in fetuses exposed just 36 hours later, however, was a surprise. These mice exhibited unique and in some cases opposing facial patterns, such as shortened upper lip, a present philtrum, and the brain, instead of appearing too narrow in the front, appeared wide.

“Overall, the results of our studies show that alcohol can cause more than one pattern of birth defects, and that the type and extent of brain abnormalities—which are the most devastating manifestation of prenatal alcohol exposure—in some cases may be predicted by specific facial features,” Sulik said. “And, importantly, alcohol can cause tremendously devastating and permanent damage at a time in development when most women don’t recognize that they’re pregnant.”


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Saturday, December 28, 2019

Scientists observe MRI to predict intelligence levels in children

Researchers from the Skoltech Center for Computational and Data-Intensive Science and Engineering (CDISE) took 4th place in the international MRI-based adolescent intelligence prediction competition. The results of their study by the Skoltech scientists were published in the journal Adolescent Brain Cognitive Development Neurocognitive Prediction.

In 2013, the US National Institutes of Health (NIH) launched the first grand-scale study of its kind in adolescent brain research, Adolescent Brain Cognitive Development – to see if and how teenagers’ hobbies and habits affect their further brain development.

Magnetic Resonance Imaging (MRI) is a common technique used to obtain images of human internal organs and tissues. Scientists wondered whether the intelligence level can be predicted from an MRI brain image. The NIH database contains a total of over 11,000 structural and functional MRI images of children aged 9-10.

NIH scientists launched an international competition, making the enormous NIH database available to a broad community for the first time ever. The participants were given the task of building a predictive model based on brain images.

In their recent study, Skoltech researchers focused on predicting the intelligence level, or the so-called “fluid intelligence”, which characterizes the biological abilities of the nervous system and has little to do with acquired knowledge or skills. Importantly, they made predictions for both the fluid intelligence level and the target variable independent from age, gender, brain size or MRI scanner used.

“Our team develops deep learning methods for computer vision tasks in MRI data analysis, among other things. In this study, we applied ensembles of classifiers to 3D of super precision neural networks: with this approach, one can classify an image as it is, without first reducing its dimension and, therefore, without losing valuable information,” explains CDISE PhD student, Ekaterina Kondratyeva.

The results of the study helped find the correlation between the child’s “fluid intelligence” and brain anatomy. Although the prediction accuracy is less than perfect, the models produced during this competition will help shed light on various aspects of cognitive, social, emotional and physical development of adolescents. This line of research will definitely continue to expand.

this is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.     
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