Certain hearts 'unfit' for donation no more

 Many hearts are declared unfit for donation due to stress-induced heart failure. But a recent study found that this condition has no bearing on the outcome of a transplant further opening path for up to 30 per cent more heart transplants.

"Systematic utilisation of these hearts would mean a breakthrough for heart transplantation, as more patients could be accepted for transplantation," said  senior lecturer. The study, is based on particulars of 641 potential heart donors in Sweden in the years 2006-2016.

Either these people, who had been declared brain-dead, had said yes to donation during their lives or their survivors had given the go-ahead. As many as 24 per cent of potential donors had acute stress-induced cardiomyopathy, or broken heart syndrome, in which cardiac function is impaired in one part of the heart, while the other parts beat normally. This condition is caused by the massive surge in stress hormones observed in the course of brain death.

The functional impairment appears to be transient: Within a few hours or days, the heart recovers. Nevertheless, there are recommendations that these hearts should not be transplanted. The selection process, therefore, varies from one location to another. To date, the transplantation centre in Gothenburg has had the favourable clinical experience of transplanting hearts with stress-induced heart failure, and there were 42 such cases in the current study.

The results show that when the donors' hearts had been subject to stress-induced heart failure, the outcomes for recipients were no different. Neither was mortality affected; rather, it conformed to the expected 20 per cent rate in both groups after ten years.

"The impairment in cardiac function seems to be temporary and is not caused by coronary artery disease or other heart diseases. This fact fits well with stress-induced heart failure. When we repeatedly examine these hearts, we see that their function recovers quickly," says the researcher.

More studies are to follow the current one, to verify the results. Ending disqualification of donors with stress-induced heart failure is seen as especially urgent since the condition arises more often in young people, whose hearts are otherwise well suited for donation. "We estimate that the supply of donor's hearts could be increased by 20-30 per cent if these hearts are used," he concluded.  


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“Organ transplant network more effective in Tamil Nadu”

The organ transplant network in Tamil Nadu was ten times more effective than the system being followed in the rest of India, said Christopher Barry, a liver transplant surgeon from New York, who is working with the Multi Organ Harvesting Aid Network (MOHAN) Foundation, here on Saturday.

“The system in Tamil Nadu could be used as a success model in other States,” said Dr. Barry speaking on the sidelines of an awareness programme on organ donation at the Indo Tibetan Border Police Force recruits training centre at Idayapatti.

According to him, 90 per cent of organ donors in India are living donors. “Transplantation of organ from deceased donors is starting to take off now. Popularising it will put an end to illegal organ trade,” Dr. Barry added. He further said that last year, 500 cases of organ transplant were reported in India. 

Addressing the recruits, he said diabetes, hyper pressure and heart ailments, which are common in India, can lead to kidney failure. “Maintain a healthy lifestyle and manage stress through meditation and regular exercise,” Dr. Barry said. 

S. Kavitha, organ transplant coordinator of MOHAN Foundation, said despite having efficient doctors, the nation is short of donors. “A large number of road accident victims suffer brain death. Several thousands of people will benefit if the organs of road accident victims, who suffer brain death, are donated,” she said. 

“Only 0.08 per cent of the entire population comes forward to donate organs. This is an issue that needs to be addressed,” she noted.

Naresh Kumar, a doctor at the ITBP centre, said that this was the first such awareness programme in the centre. “This could be an initiative to bring a change and create awareness. If organised in all training centres of CRPF, the message would reach not less than three lakh recruits,” Dr. Kumar noted.

Gopinath Choyi, commandant, S.C. Jha, second commandant, and Dr. Naresh Babu of the ITBP centre, were among those who attended the programme.

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