Infertility is associated with a higher risk of developing cancer in women of childbearing age, say researchers including one of Indian-origin.

The findings, showed that infertile women had an overall 18 per cent higher risk of developing cancer compared to women who were not infertile. 

However, the absolute risk is very low at just two per cent compared to 1.7 per cent among women who are not infertile, found researchers in the US.


"We do not know the causes of the increase in cancer that we found in this study, whether it might be the infertility itself, the causes of the infertility, or the infertility treatment," said the lead author.

"We can only show there is an association between them," she added.

For the study, the team analysed data from 64,345 infertile women who were followed for nearly four years. 

Although breast cancer was the most common in both fertile and infertile women, the team found a slightly higher risk of hormone-driven cancers of the ovary and uterus among the infertile women. 

They also found a slightly higher risk of cancers of the lung, thyroid, liver and gallbladder and leukemia among the infertile women. 

"While several of these associations were significant, it is important to note that the absolute increases in risk were modest," said the author.

"The low overall incidence of cancer among these women means that one in 49 infertile women would develop cancer during the follow-up period compared to one in 59 women who were not infertile," said another researcher.

Further research needs to be carried out to determine what factors may be influencing the long-term risk of cancer for infertile women, she  noted.

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7 Warning Signs of Breast Cancer

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While you should never skip your periodical mammogram, if you find a suspicious lump in your breast or under your armpit, you should visit your doctor immediately. Though lumps certainly need checking, there are other signs that may point to breast cancer too. Being knowledgeable about these seven signs and detecting breast cancer early on can make all the difference. Here's what you need to know:
	1. A change in the size, form or structure of the breast.
	2. A dimple in the breast or a convergence of the skin.
	3. Sudden discharge of liquid from the nipple.
	4. Itching, irritation or sudden rash on the nipple.
	5. Sudden pain in a specific spot that won't go away.
	6. The nipple suddenly becomes introverted.
	7. Bloating, redness, change of texture or color of the skin on the breast.