Friday, July 12, 2019

Novel technique to accurately detect autism in kids

Researchers have developed a new technique to help doctors more quickly and accurately detect autism spectrum disorder (ASD) in children.

Researchers  characterised how children with ASD scan a person's face differently than a neuro-typical child.

They developed a technique that considers how a child with ASD gaze transitions from one part of a person's face to another.

The use of this technology, described in the journal, makes the diagnostic process less stressful for the children and if combined with existing manual methods could help doctors better avoid a false positive autism diagnosis.

"Many people are suffering from autism, and we need early diagnosis especially in children," said a researcher.

"The current approaches to determining if someone has autism are not really child-friendly. Our method allows for the diagnosis to be made more easily and with less possibility of mistakes," she said.

"The new technique can be used in all ASD diagnosis, but we believe it's particularly effective for children,"she said.

The researchers evaluated 17 children with ASD and 23 neuro-typical children.

The mean chronological ages of the ASD and neuro-typical groups were 5.5 and 4.8, respectively.
Each participant was shown 44 photographs of faces on a 19-inch screen, integrated into an eye-tracking system.

The infrared device interpreted and identified the locations on the stimuli at which each child was looking via emission and reflection of wave from the iris.

The images were separated into seven key areas of interest (AOIs) in which participants focussed their gaze: under the right eye, right eye, under the left eye, left eye, nose, mouth and other parts of the screen.

The researchers wanted to know more than how much time the participants spent looking at each AOI, but also how they moved their eyes and scan the faces.

The researchers used four different concepts from network analysis to evaluate the varying degree of importance the children placed on the seven AOIs when exploring the facial features.

The first concept determined the number of other AOIs that the participant directly moves their eyes to and from a particular AOI.

The second concept looked at how often a particular AOI is involved when the participant moves their eyes between two other AOIs as quickly as possible.

The third concept is related to how quickly one can move their eyes from a particular AOI to other AOIs.

The fourth concept measured the importance of an AOI, in the context of eye movement and face scanning, by the number of important AOIs that it shares direct transitions with.

Currently, the two most favoured ways of assessing ASD involve a questionnaire or an evaluation from a psychologist.

"It is much easier for children to just look at something, like the animated face of a dog, than to fill out a questionnaire or be evaluated by a psychologist," said a professor.

"Also, the challenge many psychologists face is that sometimes behaviours deteriorate over time, so the child might not display signs of autism, but then a few years later, something starts showing up.

"Our technique is not just about behaviour or whether a child is focussing on the mouth or eyes. It's about how a child looks at everything," the Prof. said.


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Friday, March 22, 2013

Brain Circuitry Yields Clue to Autism


A problem with a certain brain circuit may be one reason why 7-month-old infants who later develop autism are slower to shift their gaze and attention from one object to another, compared with infants who do not develop autism.

That's the finding of a study that included 97 children who underwent an eye-tracking test and brain scan at age 7 months and a full clinical assessment at age 25 months.

The results showed that infants later diagnosed with autism were about 50 milliseconds slower in shifting their gaze from one object to another, compared with those who did not develop autism.

The study, also found that gaze shifting in infants who did not develop autism was linked with a specific circuit in the brain. This association was not found in infants who later developed autism.

These findings suggest that 7-month-old who go on to develop autism show subtle yet overt behavioural differences prior to the emergence of the disorder. They also implicate a specific neural circuit ... which may not be functioning as it does in typically developing infants, who show more rapid orienting to visual stimuli.

Autism is a developmental disability that can cause significant social, communication and behavioural challenges.

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