Diminished Ovarian Reserve Could Hamper Your Chances Of Conceiving; How To Improve Your Odds

Infertility is becoming increasingly common in this time and age. More couples are opting for fertility treatments due to their inability to conceive. There are many factors that lead to infertility in women and men. Diminished ovarian reserve is one of these causes that lead to infertility in women. In laymen's terms, diminished ovarian reserve is the loss of normal reproductive capacity due to a low egg count in a woman's ovaries.

We talked to Dr Jyoti Bali, Director, BabySoon Fertility and IVF Center to help you understand everything about diminished ovarian reserve and how it can affect your chances of having a child.

Diminished Ovarian Reserve Could Hamper Your Chances Of Conceiving; Know The Associated Risk

What is an ovarian reserve?

A woman is born with around 6 million eggs in her ovaries, which reduce to a few hundred thousand by the time she reaches puberty. An ovarian reserve refers to the quality and quantity of these eggs present in a woman's ovaries. This essentially determines her potential to reproduce. A lower count or quality of eggs in both ovaries can cause diminished ability to conceive a child.

Who is at risk?

A low ovarian reserve is primarily caused by increasing age as women move towards menopause. In fact, the reserve begins diminishing at a faster rate after the age of 35. This depletion continues to occur at an even faster rate over the next decade.

Apart from age, endometriosis, genetic abnormalities, smoking, and aggressive medical treatments like radiation can also cause a diminished ovarian reserve. However, some women are naturally born with low egg count or are susceptible to egg depletion for no known cause.

What are the symptoms of low ovarian reserve?

In most women, a decreased ovarian reserve causes no symptoms. Some women may experience a menstrual cycle that is reduced from 28 to 25 days. But for the most part, women find out they have DOR after diagnostic testing.

How does it affect the chances of fertility?

A diminished ovarian reserve directly impacts fertility as women with fewer or lower quality eggs have difficulty conceiving naturally. It also makes it tougher for women to remain pregnant since the rate of miscarriage increases as egg quality decreases. However, with treatment, women can still go on to sustain healthy pregnancies.

Is there a chance of conceiving after treatment?

Treatments like In-Vitro Fertilization (IVF) or supplementing with hormones like DHEAS (dehydroepiandrosterone sulphate) have shown incredibly positive results for women with diminishing ovarian reserves. In some cases, women with this condition can also use donor eggs or freeze healthy eggs to get pregnant at a later stage. 

What can be done to improve your odds?

Some easy yet effective ways include:

• Check your ovarian reserve by doing a simple blood test called AMH
• In case of delay in Marriage and childbearing opt for oocyte(egg) freezing/Embryo freezing
• Include a healthy lifestyle
• Maintain ideal body weight
• Balanced Nutrition diet

 

This is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.   

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How can one say if a brain is awake?

Scientists commonly use multiple electroencephalograms or EEG tests to determine the brain consciousness level but now a research team, using rats, has been able to demonstrate that the EEG doesn't always track with being awake.

The study team raised questions about what awareness entails.

One of the researcher said, EEG doesn't necessarily co-relate with behaviour. We are raising more questions and asking that people are more cautious when interpreting EEG data.

Under anaesthesia, an EEG reveals a ind of unconsciousness signature: diminished brain connections; sluggish waves which are also correlated with profound sleep, vegetative state, and coma; and less complex or less time-consuming change in brain function.

Researchers wanted to look at the results of these measures when a brain was awakened in anaesthesia based on data from a 2018 study. To do so, they examined a brain are called the medial prefrontal cortex which was shown to play a role in the focus, auto-processing and synchronization of perception.

The team used a drug that imitated neurotransmitter acetylcholine production in that part of the brain to induce some of the rats to walk about despite their continues anesthesiology. The rats were not treated with the same medication on the back of the brain. There was anaesthesia in the brain for both types of rats but only one group was 'awakened.'

Then we took the EEG data and looked at those factors that have been considered correlates of wakefulness. We figures if the animals were waking up, even while still exposed to anaesthesia, then these factors should also come back up. However, despite wakeful behaviour, the EEGs were the same in the moving rats and the non-moving anesthetized rats, said the researcher.
What does this mean for the EEG's ability to reflect consciousness?

The study does support the possibility that certain EEG features might not always accurately capture the level of consciousness in surgical patients, said a senior author.

However, EEG likely does have value in helping us understand if patients are unconscious. For e.g., a suppressed EEG would suggest a very high probability of unconsciousness during general anaesthesia. However, using high anaesthetic doses to suppress the EEG might have other consequences, like low BP, that we want to avoid. So, we will have to continue to be judicious in assessing the many indices available, including pharmacologic dosing guideline, brain activity and cardiovascular activity.

He noted that there is physiological precedent for an EEG mismatching behaviour.

For instance, the brain of someone in REM sleep is almost identical to an awake brain. No monitor is perfect, but the current monitors we use for the brain are good and do their job most of the time. However, our data suggest there are exceptions.

Their research posed interesting questions about the representation in the brain consciousness, said the researcher.

These measures do have value and we have to do more studies. Maybe they are associated with awareness and what we call the content of consciousness. With rats, we don't know we can't ask them !

this is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.     
https://gscrochetdesigns.blogspot.com. one can see my crochet creations  
https://gseasyrecipes.blogspot.com. feel free to view for easy, simple and healthy recipes    
https://kneereplacement-stickclub.blogspot.com. for info on knee replacement