Oxford University explores anti- parasitic drug ivermectin as Covid-19 treatment

The University of Oxford said on Wednesday it was testing anti-parasitic drug ivermectin as a possible treatment for Covid-19, as part of a British government-backed study that aims to aid recoveries in non-hospital settings.

Ivermectin resulted in a reduction of virus replication in laboratory studies, the university said, adding that a small pilot showed giving the drug early could reduce viral load and the duration of symptoms in some patients with mild Covid-19.

Dubbed PRINCIPLE, the British study in January showed that antibiotics azithromycin and doxycycline were generally ineffective against early-stage Covid-19.

While the World Health Organization, and European and US regulators have recommended against using ivermectin in Covid-19 patients, it is being used to treat the illness in some countries, including India.

"By including ivermectin in a large-scale trial like PRINCIPLE, we hope to generate robust evidence to determine how effective the treatment is against Covid-19, and whether there are benefits or harms associated with its use," co-lead investigator of the trial Chris Butler said.

People with severe liver conditions, who are on blood-thinning medication warfarin, or taking other treatments known to interact with ivermectin, will be excluded from the trial, the university added.

Ivermectin is the seventh treatment to be investigated in the trial, and is currently being evaluated alongside antiviral drug favipiravir, the university said. 

This is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.   

https://gscrochetdesigns.blogspot.com. one can see my crochet creations  
https://gseasyrecipes.blogspot.com. feel free to view for easy, simple and healthy recipes    
https://kneereplacement-stickclub.blogspot.com. for info on knee replacement

Immediate Use of Ivermectin Medicine Globally Can End COVID-19 Pandemic

A peer-reviewed research has claimed that global ivermectin use can end the COVID-19 pandemic, as the medicine significantly reduces the risk of contracting the deadly respiratory disease when used regularly.

The common antiparasitic ivermectin is being touted as a miracle cure for COVID-19 by doctors and campaigners the world over.

Peer reviewed by medical experts that included three US government senior scientists and published in the American Journal of Therapeutics, the research is the most comprehensive review of the available data taken from clinical, in vitro, animal, and real-world studies.

Led by the Front Line COVID-19 Critical Care Alliance (FLCCC), a group of medical and scientific experts reviewed published peer-reviewed studies, manuscripts, expert meta-analyses, and epidemiological analyses of regions with ivermectin distribution efforts all showing that ivermectin is an effective prophylaxis and treatment for COVID-19.

"We did the work that the medical authorities failed to do, we conducted the most comprehensive review of the available data on ivermectin," said Pierre Kory, MD, president and chief medical officer of the FLCCC. "We applied the gold standard to qualify the data reviewed before concluding that ivermectin can end this pandemic."

A focus of the manuscript was on the 27 controlled trials available in January 2021, 15 of which were randomised controlled trials (RCT's).

Consistent with numerous meta-analyses of ivermectin RCT's since published by expert panels from the UK, Italy, Spain and Japan, they found a large, statistically significant reduction in mortality, time to recovery, and viral clearance in COVID-19 patients treated with ivermectin.

"Our latest research shows, once again, that when the totality of the evidence is examined, there is no doubt that ivermectin is highly effective as a safe prophylaxis and treatment for COVID-19," said Paul E. Marik, founding member of the FLCCC and Chief, Pulmonary and Critical Care Medicine at Eastern Virginia Medical School.

Many regions around the world now recognise that ivermectin is a powerful prophylaxis and treatment for COVID-19. South Africa, Zimbabwe, Slovakia, Czech Republic, Mexico, and India have approved the drug for use by medical professionals.

The results, as seen in this latest study, demonstrate that the ivermectin distribution campaigns repeatedly led to "rapid population-wide decreases in morbidity and mortality".

"We are calling on regional public health authorities and medical professionals around the world to demand that ivermectin be included in their standard of care right away so we can end this pandemic once and for all," Marik noted.

This is only for your information, kindly take the advice of your doctor for medicines, exercises and so on.     

https://gscrochetdesigns.blogspot.com. one can see my crochet creations  
https://gseasyrecipes.blogspot.com. feel free to view for easy, simple and healthy recipes    
https://kneereplacement-stickclub.blogspot.com. for info on knee replacement