Chronic Stress Early In Life May Cause Anxiety, Aggression In Later Life
A group of researchers from Cold Spring Harbor Laboratory
(CSHL) conducted some tests to analyse the effects of social stress
during adolescence upon later life. A research team led by
Associate Professor Grigori Enikolopov at CSHL conducted
certain tests on mice to see the effect of stress faced in early life
on the later life. The study got published in the online journal
PLOS ONE. They took mice who were 1 month old as they are
comparatively equal to human adolescents. These mice were put
with aggressive adult male mice in separate cages. The younger
were attacked by the adult males whenever they were brought
together, causing social-defeat stress in the young mice, as
scientists term it. Subsequently, these mice were put to behavioral
tests. It was found that the young mice had increased anxiety
levels due to fear, isolation, and lack of communication with
others. As a result, they suffered from slow nerve-cell growth,
called neurogenesis. In another test, some young mice were given
similar social stress but they after some time they were removed
from such environment. In some time, they recovered their nerve-
cell growth and started to show signs of normalcy. It proved that
young mice possessed the resilience to recover biologically as
well in behavioral aspects. However, it was observed that even in
the second set of mice that showed signs of recovery, there were
two behavioral changes. Even in adulthood, the mice who had
social stress in early life used to get anxious too easily and were
more aggressive in their interactions.
(CSHL) conducted some tests to analyse the effects of social stress
during adolescence upon later life. A research team led by
Associate Professor Grigori Enikolopov at CSHL conducted
certain tests on mice to see the effect of stress faced in early life
on the later life. The study got published in the online journal
PLOS ONE. They took mice who were 1 month old as they are
comparatively equal to human adolescents. These mice were put
with aggressive adult male mice in separate cages. The younger
were attacked by the adult males whenever they were brought
together, causing social-defeat stress in the young mice, as
scientists term it. Subsequently, these mice were put to behavioral
tests. It was found that the young mice had increased anxiety
levels due to fear, isolation, and lack of communication with
others. As a result, they suffered from slow nerve-cell growth,
called neurogenesis. In another test, some young mice were given
similar social stress but they after some time they were removed
from such environment. In some time, they recovered their nerve-
cell growth and started to show signs of normalcy. It proved that
young mice possessed the resilience to recover biologically as
well in behavioral aspects. However, it was observed that even in
the second set of mice that showed signs of recovery, there were
two behavioral changes. Even in adulthood, the mice who had
social stress in early life used to get anxious too easily and were
more aggressive in their interactions.
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Labels: adolescence, aggression, anxiety, chronic, communication, early, fears, isolation, lack, neurogenesis, social, stress
posted by G S Iyer at 10:01 PM
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