Paleo diet could increase risk of heart diseases
According to the
world's 1st major study examining the impact of the diet on gut
bacteria. People who follow the paleo diet have twice the amount of a
key blood biomarker linked closely to heart disease. High levels of
biomarker, TMAO, an organic compound produced in the gut, are associated
with an increased risk of heart disease, which kills one Australian
every 12 minutes.
Researcher compared 44 people on the diet with 47 following a traditional Australian diet and measured the amount of timethylamine-n-oxide(TMAO) in participants' blood.
Impact on gut
The controversial Paleo ( or caveman) diet advocates eating meat, vegetables, nuts and limited fruit ans excludes grains, legumes, dairy, salt, refined sugar and processed oils.
Lead researcher said that the diet's growing popularity, it was important to understand the impact it could have on overall health.
Many Paleo diet proponents claim the diet is beneficial to gut health, but this research suggests that when it comes to the production of TMAO in the gut, the Paleo diet could be having an adverse impact in terms of heart health, she said.
We also found that populations of beneficial bacterial species were lower in the Paleolithic groups, associated with the reduced carbohydrate intake, which may have consequences for other chronic diseases over the long term.
Reduced intake of grains to blame
She said the reason TMAO was so elevated in people on the paleo diet appeared to be the lack of whole grains in their diet.
We found the lack of whole grains were associated with TMAO levels, which may provide a link between the reduced risks of cardiovascular disease we see in populations with high intakes of whole grains, she said.
The researchers also found higher concentrations of the bacteria that produces TMAO in the Paleo group.
The Paleo diet excludes all grain and we know that whole grains are a fantastic source of resistant starch and many other fermentable fibres that are vital to the health of your gut microbiome, the Dr. said.
Because TMAO is produced in the gut, a lack of whole grains might change the populations of bacteria enough to enable higher production of this compound.
Additionally, the Paleo diet includes greater servings per day of red meat, which provides the precursor compounds to produce TMAO, and Paleo followers consumed twice the recommended level of saturated fats, which is cause for concern.
Researcher compared 44 people on the diet with 47 following a traditional Australian diet and measured the amount of timethylamine-n-oxide(TMAO) in participants' blood.
Impact on gut
The controversial Paleo ( or caveman) diet advocates eating meat, vegetables, nuts and limited fruit ans excludes grains, legumes, dairy, salt, refined sugar and processed oils.
Lead researcher said that the diet's growing popularity, it was important to understand the impact it could have on overall health.
Many Paleo diet proponents claim the diet is beneficial to gut health, but this research suggests that when it comes to the production of TMAO in the gut, the Paleo diet could be having an adverse impact in terms of heart health, she said.
We also found that populations of beneficial bacterial species were lower in the Paleolithic groups, associated with the reduced carbohydrate intake, which may have consequences for other chronic diseases over the long term.
Reduced intake of grains to blame
She said the reason TMAO was so elevated in people on the paleo diet appeared to be the lack of whole grains in their diet.
We found the lack of whole grains were associated with TMAO levels, which may provide a link between the reduced risks of cardiovascular disease we see in populations with high intakes of whole grains, she said.
The researchers also found higher concentrations of the bacteria that produces TMAO in the Paleo group.
The Paleo diet excludes all grain and we know that whole grains are a fantastic source of resistant starch and many other fermentable fibres that are vital to the health of your gut microbiome, the Dr. said.
Because TMAO is produced in the gut, a lack of whole grains might change the populations of bacteria enough to enable higher production of this compound.
Additionally, the Paleo diet includes greater servings per day of red meat, which provides the precursor compounds to produce TMAO, and Paleo followers consumed twice the recommended level of saturated fats, which is cause for concern.
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Read more at Speciality Medical Dialogues: Paleo diet may increase risk of Heart disease: European Journal of Nutrition https://speciality.medicaldialogues.in/paleo-diet-may-increase-risk-of-heart-disease-european-journal-of-nutrition/
Read more at Speciality Medical Dialogues: Paleo diet may increase risk of Heart disease: European Journal of Nutrition https://speciality.medicaldialogues.in/paleo-diet-may-increase-risk-of-heart-disease-european-journal-of-nutrition/
Labels: concentration, few fruits, heart diseases, impact on gut, increases risk of, key blood biomarker, organic compound, Paleo diet, red meat, reduced grains n legumes, triple TMAO levels, vegetables
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