Tuesday, August 22, 2017

New tool developed for diabetes patients at risk for low blood sugar emergencies

According to a recent research, a group of researchers have found and validated a practical tool for identifying diabetes patients who are at the highest risk for being admitted to an emergency department or hospital due to severe hypoglycemia, or very low blood sugar. 

Advances in care and improved treatment options have reduced the risk of long-term complications and death for more than 25 million who have diabetes, which is characterized by high blood sugar. 

A senior research scientist and the study's lead author, said, “Sometimes a person with diabetes is unaware that their blood sugar is dropping and can progress quickly into severe hypoglycemia, which has been associated with falls, automobile accidents, heart attacks, coma, and even death.”

Adding, “Hypoglycemia is often preventable with the proper clinical attention, and we believe this tool will help focus that attention on the patients who most need it.” 

With an estimated 100,000 hypoglycemia-related adverse events resulting in emergency room visits each year , hypoglycemia is now one of the most frequent adverse events in patients with type two diabetes. 

Older patients and those with a longer history of diabetes are particularly susceptible, noted the researcher.The study developed the hypoglycemia risk stratification tool by identifying 156 possible risk factors for hypoglycemia and collecting data from more than 200,000 patients with type two diabetes receiving care from a hospital. 

Using machine-learning analytical techniques, they developed a model to predict a patient's 12-month risk of hypoglycemia-related emergency department or hospital use.

The final model was based on six variables: number of prior episodes of hypoglycemia-related emergency department visits or hospitalizations; use of insulin; use of sulfonylurea (an oral medication commonly used to treat diabetes); severe or end-stage kidney disease; number of emergency room visits for any reason in the past year; and age. 

The researchers created a practical tool to categorize patients into high (greater than five percent), intermediate (one to five percent) or low (less than 1 percent) annual risk of hypoglycemia-related emergency department or hospital utilization. 

The  development of the tool for identifying patients at risk of hypoglycemia under their Safe Use Initiative, a collaborative effort to reduce adverse events related to medication use, including diabetes medications linked to an increased risk of hypoglycemia.

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